Metal Toxicology

Question 1

Name the 11 metals of concern

Answer 1

Lead, Tin, Aluminum, Mercury, Arsenic, Copper, Cadmium, Chromium, Nickel, Silver, Zinc,

Question 2

What is the issue with Aluminum and acid precip?

Answer 2

Acid precip lowers the pH to the point that dissolved Al in the water can become toxic

Question 3

Minamata disease occurs from bioaccumulation of _______

Answer 3

Mercury

Question 4

Metals…
Density - high or low?
Ions formed in solution - positive or negative?
React by giving up ______.
Chemical activity - reactive or non-reactive?

Answer 4

High density
Positive ions formed in sol’n
React by giving up electrons
Chemically reactive

Question 5

“Heavy” metal is any metal w/ an atomic weight > than that of _____ (__._)

Answer 5

sodium (22.9)

Question 6

This metal has been used as a medicine since ancient times

Answer 6

arsenic

Question 7

Arsenic inhibits enzymes in __________

Answer 7

Mitochondria

Question 8

This metal impairs tissue respiration and ATP activity, and is carcinogenic

Answer 8

Arsenic

Question 9

This metal is an essential nutrient, but interferes w/ membranes, altering the permeability of diff essential ions; it also binds to gills and its most toxic form is the free metal ion and mono hydroxide form

Answer 9

Copper

Question 10

This metal was used in electroplating, galvanization, paint pigment, and batteries; it’s found in cigarettes, can have negative pulmonary impacts, and can concentrate in liver and viscera

Answer 10

Cadmium

Question 11

This metal is an essential nutrient, a mutagen, teratogen, and a carcinogen

Answer 11

Chromium

Question 12

Which form of Chromium is more toxic; trivalent or hexavalent?

Answer 12

Hexavalent

Question 13

True or false: lead is an essential nutrient

Answer 13

False

Question 14

The non-essential nutrient that is liquid at room temp, is found in fluorescent lights; affects the CNS, is highly soluble; strongly binds to and mimics proteins

Answer 14

Mercury

Question 15

Essential nutrient; necessary for normal growth; carcinogenic

Answer 15

Nickel

Question 16

Free ion is toxic; rapidly complexed and sorbed; there are discharges from photographic industry;

Answer 16

Silver

Question 17

essential nutrient; free ion is toxic; affects gills & ion exchange; targets pancreas & bone in birds and mammals;

Answer 17

Zinc

Question 18

Water quality standard for most metals is a ______-based equation

Answer 18

hardness

Question 19

metals can form _______ w/ other compounds

Answer 19

complexes

Question 20

In a complex, the “attaching group” is called a ______

Answer 20

ligand

Question 21

Complexes form _____ _____ bond

Answer 21

Coordinate covalent

Question 22

The ____ ____ Model was primarily developed for Copper

Answer 22

Biotic Ligand