Pagets Disease Flashcards
1
Q
Pagets Disease descripton
A
“OSTEITIS DEFORMANS”
YOUNG (5-20 yo) Asymptomatic enlargement of bone
Pseudo-fx, path fx, and skeletal deformities common
2
Q
Pagets Disease pain
A
Pain – insidious, dull, Nite Pain, not affected by activity
3
Q
Pagets Disease location
A
Polyostotic, LE>UE, R>L. L3-4, low Tx, upper Cx MC in spine. lytic/sclerotic or mixed, ↑bone density, coarsened trabeculae, expansile
4
Q
Pagets Disease plain film
A
Spine: ivory vert., “picture frame vert”; Skull: osteoporosis circumscription & “cottonwool”; fem/tib: “candle flame/ blade of grass” appearance
5
Q
Pagets Disease ddx
A
Lab: ↑serum AP, ↑urinary hydroxyproline, normal to hypercalcemia
6
Q
Pagets Disease malignant/refer?
A
0.9-2%
Refer if path fx
Need Rx for calcitonin/ diphosphonates
