Ewing's Sarcoma

Question 1

Ewing’s Sarcoma description

Answer 1

YOUNG/ADULT (10-25 yo) Marrow cell tumor; “round cell”; UNcommon in blacks

Question 2

Ewing’s Sarcoma SX

Answer 2

pain, swelling; local warmth, tenderness, dilated veins; often palpable soft tissue mass, mimics infection

Question 3

Ewing’s Sarcoma location

Answer 3

Long bones (70% - Femur, tibia, fibula, humerus); diaphysis is classic location. Flat bones (25% - Pelvis, ribs, scapula)
Spine (only 5%)
Cortical saucerization

Question 4

Ewing’s Sarcoma plain film

Answer 4

mixed (permeative/lytic), wide zone of transition; laminated periosteal response in 25-50% (this all just describes a primary malignancy) - - so without lab findings, we’d choose osteosarcoma

Question 5

Ewing’s Sarcoma ddx

Answer 5

Osteosarcoma

Question 6

Ewing’s Sarcoma other

Answer 6

LAB: fever, anemia, leukocytosis, ↑ ESR (mimics infection); MC 1° malignant bone tumor to metastasize to bone; metastasis to lungs common