Page 26 - Flashcards
No cell wall, atypical
LENGTHY SIGNS AND SYMPTOMS (walking pneumonia) but treatable
Requires specialized lab testing
common in school-aged/young adults (military boot camp, e.g.)
mycoplama pneumoniae
Small, coccobacilli (obligate intracellular parasite)
Various species causing fever/typhus
Rickettsia
Orienta
Spotted fever?
RMSF - tick - R. rickettsii
Epidemic typhus (classical)
Louse - R. Prowazekii
bio threat agent
Murine typhus
Flea - R. typhi
Scrub typhus
Mite (or chiggers) - O. tsutsugamushi
Abrupt onset, fever (2-3 weeks), HA, DEEP muscle pain, rash (PALMAR/PLANTAR rash)
no eschar/location not at site of entry
Rickettsia/Orientia
Atypical bacteria - obligate intracellular parasite
Bio threat agent
Q fever
Coxiella burnetti
Highly infectious/communicable through body fluids/aerosol
high fever, HA, myalgias, athralgias, cough, multiple organs…
nonspecific ssx, so think source… near animals (sheep, goats, cattle)
Q fever
coxiella burnetti (obligate intracellular parasite)
Polypeptides/free lipids (waxes/mycosides - highly impervious to aqueous material)
Arabinogalactan layer (mycolic acids)
NAG/NAM
Cytoplasmic membrane
Mycobacterium tuberculosis
Waxes, myosides, cord factor (in free lipid layer)?
TB virulence factors
1 infectious disease in the whole known universe
TB
Mild and often asymptomatic (flu-like symptoms possible)
Cell Mediated Immunity slows the growth and causes inflammation – process takes about 30 days from initiation of infection
Bacteria are contained within tubercles – small granulomas consisting of epithelioid and giant cells. Granuloma formation is partly caused by cord factor
TB primary
No clinical symptoms
No shedding of bacteria
Skin test positive; chest xray probably negative
No true medical disease, just potential presence of live bacteria within tubercules
TB Latent phase
Skin test at end of primary TB would be…
positive
(probably negative CXR)
Probably wouldn’t treat at this (primary) stage… except in the military
