Page 11: Acquired Immunity

Question 1

For long term immunity to occur host must mount an _ immune response

Answer 1

acquired

Question 2

Acquired immune responses are highly specific and have the capacity for immunological _ and increased _

Answer 2

memory, efficiency

Question 3

The acquired immune response is triggered by the recognition of microbial antigens (usually _)

Answer 3

proteins

Question 4

Microbial antigens are recognized by _, -

Answer 4

Immunoglobulins, t-cells

Question 5

Immunoglobulins include _ _ _ on -, and secreted _ from terminally differentiated B cells referred to as _ _

Answer 5

B cell receptors (BCRs), B-cells, antibodies, plasma cells

Question 6

T-cells have _ _ _

Answer 6

T cell receptors

Question 7

The acquired immune response manifests as _ or _

Answer 7

AbMIR, CMIR

Question 8

AbMIR is known as _ _ _ _ and targets _ pathogens

Answer 8

Antibody Mediated Immune Response, extracellular

Question 9

CMIR is known as _ _ _ _ and targets _ pathogens

Answer 9

Cell mediated immune response, intracellular

Question 10

IL-4 & IL-13 drive the _ response

Answer 10

AbMIR

Question 11

IFNy drives the _ response

Answer 11

CMIR

Question 12

Time to mount acquired immune response is _ than innate response, and is more _

Answer 12

longer, effective

Question 13

Acquired immune response takes longer because there is a _ level of immune system orchestration

Answer 13

higher

Question 14

For acquired immune response to occur there must be sufficient _ to activate _ cells

Answer 14

inflammation, surveillance

Question 15

Summary of Acquired Immune Response

Answer 15

1. Phagocytosis and killing of the microbe
2. Processing microbial protein’s into peptides
3. Migration from site of infection to lymphoid tissue
4. Upregulation of MHC and binding of antigen to MHC
5. TCR of t-cell binds to antigen

Question 16

Antigen specific t-cells become activated, multiply, and terminally differentiate into the effector T cells of the _ immune system

Answer 16

acquired

Question 17

example of an effector t-cell is

Answer 17

cytotic T-cells

Question 18

Antigen specific _ cells may also recognize the microbial antigens, and with the help of an antigen specific _ _ cell, _ cells may become activated, multiply, terminally differentiate into _ b-cells

Answer 18

B, T helper, B, effector

Question 19

_ B and T cells are also generated during the acquired immune response to facilitate - immunity

Answer 19

Memory, long-term

Question 20

Innate immune response provides _ protection and is needed to mount _ immune response

Answer 20

immediate, acquired