Paeds Flashcards
Give hx structure in paeds minus developmental hx
- PC + HPC:
a. Feeding - volume + frequency
b. Vomiting
c. Fever
d. Wet nappies?
e. Stools - consistency and look- PMH:
a. Antenatal period
b. Birth - deliver, premature, birth weight
c. Neonatal period - illnesses and admissions
d. Medical conditions
e. Surgeries - Drug history + allergies
- Weight, height & Developmental history (milestones):
a. 6 weeks - smiles and lifts head
b. 6 months - rolls over, moves objects hand to hand, social
c. 8 months - sits unsupported
d. 12 months - pincer grip, 2 syllable words, stranger anxiety, unstable walking
e. 15 months - stable walking, points at what they want
f. 18 months - scribbles with crayons
g. 2 years - 2/3 word sentences, up & down stairs
h. 3 years - stands on one foot, counts to 10, can dress and undress
i. 4 years - hops on 1 foot, toilet trained - Immunisations
- Dietary history:
a. Special requirements
b. Type of food - FHx
- SHx:
a. Foreign travel
b. Second hand smoke
- PMH:
Average birth weight
3.5kg
when should micturition and meconium occur post birth?
- Micturition - within 24hr
* Meconium - within 48hr
How much milk should a baby have?
150 ml/kg per day
Give caloric needs of a 0-1 and 1+ yr old
○ 0-1 - 110kcal/kg/day
○ 1yr+ - 1000 + (100xage) kcal/day
Maintenance fluids of child
Maintenance fluids:
1st 10kg - 100 ml/kg/day
2nd 10kg - 50 ml/kg/day
Subsequent kg - 20ml/kg/day
Give 3 benefits of breast feeding to mum and baby
Benefits to baby: • More easily digested • Antibodies that fight infection • Lowers risk of allergies • Fewer hospitalisations • Higher IQ in later life • Bonds with mother • Lowers risk of SIDS
Benefits to mother:
• Bonds with baby
• Burns calories so lose baby weight
• Releases oxytocin which reduces uterine bleeding after birth
• Lowers risk of breast and ovarian cancer
• Saves money
Paed wheeze differentials
Wheeze: • Pneumonia • Asthma • Bronchiolitis • Bronchitis • Cystic Fibrosis • Inhalation of foreign body • Aspiration
Paeds acute cough differentials
Acute Cough: • Upper airways: ○ Rhinovirus ○ Croup ○ Allergy • Lower airways: ○ Asthma ○ Bronchitis, bronchiolitis
Paeds chronic cough differentials
Chronic cough: • Upper airways: ○ Infection - chronic sinusitis, tonsillitis ○ GORD • Lower airways: ○ Asthma ○ Foreign body ○ Bronchiectasis ○ CF • Psychogenic cough
Paeds stridor differentials
Stridor: • Nose and nasopharynx: ○ Inflammation eg rhinitis and sinusitis • Mouth: ○ Tonsillar hypertrophy ○ Foreign body • Larynx: ○ GORD ○ Epiglottitis ○ Abscess ○ Foreign body • Trachea: ○ Tracheomalacia ○ Tracheitis
S&S of asthma in paeds
History: • Cough after exercise • SOB • Limited exercise • Peak in school age (4)
Examination:
• Barrel shaped chest
• Hyperinflation
• Wheeze and prolonged expiration
Ix of asthma paeds
Investigation:
• PEFR <80% predicted
• Bronchodilator response to beta agonist
Tx of asthma paeds
Management:
1. ICS + SABA 2. + LABA (>5yrs) or montelukast (<5yrs) 3. a. Response to LABA? - increase b. No response to LABA? - Get rid of + increase ICS 4. Increase ICS or + theophylline 5. Daily oral steroid
Consider moving up if using 3+ doses of SABA a week
ALWAYS USE SPACER
S&S of CF
History: • Cough and wheeze - recurrent chest infections • SOB • Sputum • Haemoptysis • Pale fatty stools - malabsorption • Weight loss - failure to thrive • Neonates - meconium ileus
Ix of CF
Ix:
• Sweat test
• CXR - hyperinflation, infiltrates
Tx of CF
Tx: • Non pharm: ○ Physiotherapy ○ Annual flu immunisation ○ High calorie diet ○ Pancreatic enzyme supplements ○ Multivitamins • Pharm: ○ Abx ppx ○ Bronchodilators ○ Mucolytics ○ Azithromycin - anti inflammatory and abx
S&S of bronchiolitis
History: • Dry cough • Wheeze • Feeding problems • Apnoea episodes
Examination: • Resp distress • Dry cough • Tachypnoea • Subcostal and intercostal recession • Prolonged expiration • Wheeze and crackles
Ix of bronchiolitis
Ix:
• Pulse oximetry
• CXR - hyperinflation, patchy change
• Nasopharyngeal swab
Tx of bronchiolitis
Tx:
• Oxygen
• If tachypnoea - limit oral feeds and use NGT
• Bronchodilators for wheeze
• Mechanical ventilation for apnoea or severe resp distress
Cause of croup
parainfluenza virus
S&S of croup
Symptoms: • Barking cough • Stridor • SOB worse at night • Fever
Tx of croup. Epi
Tx: • Paracetemol • Oral Dexamethasone • Adrenaline neb • Oxygen
Epi:
• 6 mths to 6 years
• Peak age of 2
Epi, S&S and tx of epiglottitis
Epi:
• 1-6 years
S&S: • Fever • Toxic looking child • Stridor • Drooling • Minimal cough
Tx:
• Urgent review to secure airway
• IV abx
s&s of pneumonia
History:
• Fever
• SOB
• Cough
Examination:
• Resp distress signs
• Desaturation and cyanosis
• Dullness to percussion, crackles, decreased breath sounds, bronchial breathing
Ix of pneumonia
BOXES
Ix: • Sputum • Blood culture • CXR • Pleural fluid if pleural effusion
Tx of pneumonia
Tx:
• Amoxicillin or erythromycin
• Severe- co amox
• HAP (48 hrs post admission) - piperacillin with tazobactam
cause of whooping cough
bordetella pertussis
S&S, ix and tx of pertussis
History:
• Coughing bouts - worse at night and after feeding.
• May vomit
• Inspiratory whoop
Ix:
• Nasal swab culture
• PCR and serology
Tx:
• Azithromycin
CXR finding of neonatal resp distress syndrome
CXR:
• Diffuse ground glass lungs
• Bell shaped thorax
Centor criteria and tx
The Centor criteria* are as follows: • presence of tonsillar exudate • tender anterior cervical lymphadenopathy or lymphadenitis • history of fever • absence of cough
3+ = cause is Group A beta hemolytic Strep
Tx:
• <3 = Paracetemol
• 3+ = phenoxymethylpenicillin or erythromycin
S&S of HF in paeds
History: • Sweating • Breathless, • Tachypnoea • Poor feeding • Failure to thrive • Tachycardia
Tx of HF in paeds
Tx:
• Diuretics
• ACEi
Causes of vomiting acute in paeds
○ GI infection
○ GI obstruction eg pyloric stenosis
Poisoning
Causes of chronic vomiting in paeds
• Chronic: ○ Peptic ulcer disease ○ GORD ○ Chronic infection Gastritits
ix of vomiting in paeds acute and chronic
Ix:
• FBCs, U&E, Creatinine
• Stool for culture
• AXR
Chronic:
• +Abdo USS
• +Endoscopy
Causes of constipation paeds
Causes: • Commonest - Low fibre, lack of exercise, poor colonic motility (FHx) • Hirschprungs • Partial obstruction • Coeliac disease • Infection • Hypercalcaemia
Tx for constipation
Tx:
• Diet - increase fluid and fibre, natural laxatives eg fruit juice
• Behavioural measures - toilet footrests, regular 5 mins toilet time after meals
• Treat for as long as constipation has been there:
○ Movicol (1st line) or lactulose
○ Enemas if no response
Causes of failure to thrive
Causes: • 95% caused by malnutrition • Organic causes: ○ GI problems ○ GORD ○ DM ○ Malabsorption ○ CF
Causes of jaundice
Unconjugated causes:
• Hemolysis
• Gilbert syndrome
Mixed causes (liver damage):
• Infection
• Drugs - eg paracetemol OD or TB drugs
• Wilsons disease
Conjugated causes (bile tract obstruction):
• Biliary atresia
• Primary sclerosing cholangitis
• CF
Ix of jaundice
Ix:
• Liver biopsy
• USS
• Bloods
GORD paeds S&S
History: • Oesophagitis • Failure to thrive • Apnoea • Regurgitation
Ix of GORD and tx
Ix:
• Upper GI endoscopy
• CXR
• Barium Swallow
Tx:
• Position babies head 30 degrees above prone
• Avoid food before sleep
• Thicker milk feeds for babies and small frequent meals
• Omeprazole if oesophagitis and gaviscon
S&S of gastroenteritis
History: • Diarrhoea • Vomiting • Crampy abdo pain • Fever • Dehydration
ix and tx of gastroenteritis
Ix:
• Stool and blood culture
• Sigmoidoscopy if IBD suspected
Tx:
• Rehydration
Consider ampicillin if scoring for sepsis
pyloric stenosis hx
Presents in weeks 2 - 4 of life with vomiting
History:
• Projectile vomiting, 30 mins after feed
• Constipation and dehydration
• Palpable mass in upper abdomen
• Hyochloremic, hypokalaemic alkalosis due to vomiting
Intussesception epi and S&S
Epidemiology:
• Affects 6-18 months old.
• 2:1 M:F
S&S: • Paroxysmal abdo colic pain • Child draws knees up and turns pale • Vomiting • Blood stained stool • Sausage shaped mass in RLQ
Ix and tx of intussesception
Ix:
• USS
Tx:
• Reduction by air insufflation
• Surgery if signs of peritonitis
Allergic colitis patho and S&S
Commonest cause of non infective diarrhoea in infants
S&S:
• Diarrhoea with blood and mucus
• Failure to thrive
• Most common allergen is cows milk protein
Ix and tx for allergic colitis
Tx:
• Exclude allergies from diet and offer substitute
Ix:
• Eosinophilia
• Raised IgE
• Positive skin prick test to specific foods
S&S of malrotation
S&S:
• Infant - bile stained vomiting
• Older child - GORD, vomiting, abdo pain
Hirschprung S&S. ix
Presentations:
• Neonatal period - failure or delay to pas meconium
• Bilious vomiting, abdo distension, constipation
• Older children - constipation, abdo distension
Ix:
Rectal biopsy
Necrotising enterocolitis S&S
Symptoms: • Feeding intolerance • Abdo distension • Bloody stools • Commonly Occurs in neonates <3 months old
Coeliac disease S&S and ix
History - Coincides with introduction of gluten in diet: • Failure to thrive • Diarrhoea • Abdo distension • Foul smelling stools
Ix:
• Jejunal biopsy showing villous atrophy
• TTG antibodies
S&S of meningitis in young and older children
S&S:
• Young children - fever, poor feeding, bulging fontaneles
• Older children - headache, neck stiffness, photophobia, kernigs sign
Anaphylaxis emergency tx
Algorithm - Signs of shock, SOB, or Stridor:
1. High flow oxygen 2. IM adrenaline 1 in 1000, 10 micrograms - repeat in 10-15 mins if no improvement 3. a. If wheezing - Neb salbutamol b. If croupy - Neb adrenaline c. If systemic symptoms of shock - fluid bolus up to 30ml/kg 4. Antihistamines and oral steroids for 72 hours. 5. Allergy clinic follow up + consider epi pen
Tx of UTI in paeds
Tx:
• <3 mths old - immediate referral to paediatrician
• >3mths + pyelonephritis - admission
• >3 mths + cystitis - trimethoprim for 3 days + safety net
Tx of Minimal change GN
Tx:
• Steroids
• Cyclophosphamide if steroid resistant
S&S of henoch shenolein purpura
patho
S&S:
• Palpable purpuric rash over buttocks and extensors
• Abdo pain
• Polyarthritis
• Features of IgA nephropathy - Haematuria and renal failure
Patho:
• IgA mediated small vessel vasculitis
• Usually seen in children following infection
Epi and tx of henoch schonlein purpura
Peak - 4-6 yrs
Tx:
• Analgesia for arthralgia
• Supportive tx for nephropathy
Undescended testes tx
Tx:
• Watch and wait
• If undescended by 9 mths refer to urologist
Tx of absence seizure
sodium valproate
S&S of tuberous sclerosis
S&S: • Cutaneous: ○ Rough skin patches over lumbar spine ○ Café au lait spots ○ Depigmented ash leaf spots which fluoresce under UV light • Neuro: ○ Development delay ○ Epilepsy ○ Intellectual impaired
Ix of tuberous sclerosis
Ix:
• CT head
• Gene studies
Causes of cerebral palsy
Patho:
• Insult to developing brain
Causes: • Ischemia • Congenital infection • Neonatal meningitis • Premature
S&S of cerebral palsy
S&S:
• Spastic - increased tone, reduced power
• Dystonic - involuntary movements
• Ataxic - wide gait, nystagmus, intention tremor
Hydrocephalus S&S and ix
S&S: • Irritability • Poor feeding • Headaches • Vomiting • Seizures • Enlarging head size • Widened sutures • Bulging fontanelles • Papilloedema
Ix:
• Cranial CT
Febrile convulsions S&S
S&S:
• Brief generalised tonic clonic seizure with fever
Ix and tx of febrile convulsions
Ix: • Urine dipstick • Inflammatory markers • CXR • LP if indicated • Consider EEG and brain imaging if concerned
Tx:
• Parental reassurance
• Abx if needed
• BZD if seizure >5 mins
S&S of duchennes and ix
S&S: • Waddling gait • Speech and motor delay • Proximal weakness • Gowers' sign +ve • Muscle wasting
Ix:
• Elevated CK
• Abnormal EMG and nerve conduction
• Muscle biopsy
S&S of hand foot and mouth disease and tx
History:
• Mild systemic upset - sore throat, small fever
• Oral ulcers
• Vesicles on palms and soles of feet
Tx:
• Hydrate + analgesia
• Reassurance
• No need to exclude from school
Patho of hypoxic ischemic encephalopathy and S&S
Pathology:
• Neonatal brain injury secondary to asphyxia during pregnancy or labour
S&S:
• Mild - increased tone and reflexes, poor feeding, staring eyes
• Moderate - lethargy, reduced tone and reflexes, seizures
• Severe - coma, reduced tone, multi organ failure
Ix and tx of hypoxic ischemic encephalopathy
Ix:
• EEG
• MRI brain
Tx:
• Resp and circ support
• Anticonvulsants
Cx of prematurity
Cx: • RDS • Persistent ductus arteriosus • Retinopathy of prematurity • Sepsis
RDS patho, S&S, and tx
RDS: • Patho - lack of surfactant in lungs • S&S - resp distress, tachycardia, hypoxia, CXR has ground glass appearance • Tx - Antenatal steroids, resp support • Cx - chronic lung disease
PDA patho, S&S, tx
Patent ductus arteriosis:
• Patho - left-right shunting, fluid overload –> HF
• S&S - continuous murmur, bounding pulses, wide pulse pressure
• Tx - Fluid restriction, indometacin, surgery to ligate duct
• Cx - HF
Retinopathy of prematurity patho, S&S, tx
Retinopathy of prematurity: • Patho - Proliferation of frail BVs • S&S - asymptomatic • Tx - Laser therapy if severe • Cx - Retinal detachment, severe visual impairment
Causes of first 24 hr jaundice in neonate
• Hemolysis eg Rh disease
• Sepsis
Red cell membrane defects
Causes of post 24 hr jaundice in neonates
day 2-14
Physiological/breast milk
hemolysis, sepsis, red cell defects
2 wks +:
• Unconjugated - breast milk, UTI, hypothyroidism, as above
Conjugated - biliary atresia, neonatal hepatitis
Ix of neonatal jaundice
FBC, blood group, LFT
Direct Coombs test
TFT
Causes of neonatal sepsis
Causes: • PROM >24 hrs • Maternal sepsis • Chorioamnionitis • Maternal carriage of GBS • Prematurity
S&S of neonatal sepsis
S&S: • Resp distress • Apnoea • Poor feeding • Temp instability
S&S of scarlett fever, tx
History: • Fever • Malaise • Tonsillitis • Strawberry tongue • Rash - pinhead erythema appearing first on torso and spares face
tx - penicillin v
S&S of CNS tumours paeds
S&S:
• Early morning headache/vomiting
• Focal neuro signs
• Papilledema
Ix and tx of CNS tumours
Ix: • MRI brain Tx: • Surgery • Chemoradiotherapy
What is wilms tumour. S&S
Patho:
• Nephroblastoma
S&S: • Painless abdo swelling • Haematuria • Weight loss • HTN
Ix and tx of wilms tumour
Ix:
• CT staging
• Biopsy
Tx:
• Surgical resection
• Chemotherapy
S&S and tx of bone tumours
S&S:
• Pain
• Swelling
• Pathological fractures of long bones
Tx:
• Surgical excision
• Endoprosthetic replacement
Downs syndrome associations
hypothyroid, hirschprung, epilepsy, PDA, tetralogy of fallot
Cx of turners. chromosomes?
Cx:
• Coarctation of aorta
• Infertile
45,X
Kleinfelters S&S. chromosomes?
S&S: • Tall stature • Hypogonadism and small testes • Gynaecomastia • Behavioural problems
47,XXY
S&S of autism
S&S: • Delay in speech and language skills • Repetitive behaviour • Poor eye contact • Rigidity of thought • Lack of imagination
Tx of autism
Tx:
• Education
• OT
• SALT
Tx of ADHD
Tx:
• Methylphenidate
• CBT
Tx of breath holding attacks
Benign and self limiting
developmental hx
a. 6 weeks - smiles and lifts head
b. 6 months - rolls over, moves objects hand to hand, social
c. 8 months - sits unsupported
d. 12 months - pincer grip, 2 syllable words, stranger anxiety, unstable walking
e. 15 months - stable walking, points at what they want
f. 18 months - scribbles with crayons
g. 2 years - 2/3 word sentences, up & down stairs
h. 3 years - stands on one foot, counts to 10, can dress and undress
i. 4 years - hops on 1 foot, toilet trained