Paediatric Shock Flashcards
What is shock?
Lack of perfusion to the peripheries leading to a lack of adequate cellular metabolism, leading to the accumulation of cellular waste
What features are suggestive of septic shock?
- Localising symptoms
- Fulminant DIC with purpuric rash
- NOT FEVER
Are patients with septic shock febrile?
NO. Fever is not the defining feature of septic shock. May be cold, euthermic or febrile.
What causes cold septic shock?
- Cardiac dysfunction due to lactic academy from septic process
- Children cannot increase SV, only inc HR to inc CO
What is warm septic shock? Features?
Vasodilatory:
- fever
- bounding pulse
- wide pulse pressure
Young or older children more likely to present with warm septic shock?
The older the child, the more likely warm shock.
Mx septic shock?
Resuscitation Pod.
- ABCs
- Prompt ABx (within 30minutes of arrival).
- Fluid resuscitation
- Consider inotropes
- Fluid, inotrope resistant = ECMO
Components of C in primary survey of septic shock?
- 2x IV access attempts; prepare for IO / umbilical
- Bloods: B/C, BSL, VBG (for lactate)
Organisms to cover and ABx for neonates with septic shock?
Neonates (GBS, E coli, Listeria):
- empirical: benzylpenicillin, cefotaxime.
- If UTI: add gentamicin.
Older children: ABx and organisms in septic shock?
Older children (Staph, strep, meningicoccal ):
- flucloxacillin
- 3rd generation ceph (cefotaxime or ceftriaxone) for BBB access
Immunocompromised / neutropenic patients: ABx and organisms to cover in septic shock?
- Tazocin: cover pseudomonas
- Vancomycin (MRSA)
Approach to fluid resuscitation in paediatric septic shock?
20ml/kg NS - 40ml/kg (in older children), then stand at the bed to watch the HR, peripheral perfusion
• With rapid assessment of another bolus, continue to bolus them
• Start drawing up inotropes if starting 40ml/kg
Neonatal be careful: as sepsis can masqeurade cardiogenic shock (CHD)
Why do septic shock patients respond poorly to fluid resuscitation?
Fluids resuscitation - do not respond as well to this because they have leaky vessels
Why is warm septic shock v cold septic shock important to determine when giving inotropes?
- Warm shock, the problem is vasodilation: therefore give NA to vasoconstrict
- Cold shock: adrenaline to increase pump
Why do neonates often get started on dobutamine?
Shock is more commonly cariogenic and cold septic shock.