Kawasaki Diseae

Question 1

Distribution Kawasaki disease?

Answer 1

Medium vessel vasculitis with predilection for coronary arteries

Question 2

What is the aetiology of KD?

Answer 2

Unknown. Likely triggered by infection.

Question 3

Peak age KD?

Answer 3

3mo - 5y

Question 4

What are the diagnostic criteria of KD?

Answer 4

Fever persisting 5d+ AND
4 of:
-1. Bilat conjunctival injection
-2. Red injected, fissured lips, strawberry tongue, injected pharynx
-3. Peripheral changes (oedema or desquamation)
-4. Polymorphous rash
-5. Cervical lymphadenopathy (1.5cm+)

Question 5

What is atypical KD?

Answer 5

Less than 5/6 criteria BUT coronary artery involvement

Question 6

Mx KD?

Answer 6

• High dose aspirin while febrile
• Low dose in subacute phase until platelets normalise (longer if coronary involvement)
• IVIG within 10d onset reduces coronary aneurysm formation
• Echo at diagnosis and 3 months

Question 7

What are the complications of KD?

Answer 7

-coronary artery vasculitis with aneurysm formation (20-25% untreated); under 5% with IVIG