Packet 4 Female Reproductive System Flashcards
T-F–the female reproductive system consists of only internal organs?
False–external genitalia too
The reproductive organs in the female are incompletely developed in the newborn until what?
gonadotrophic hormones are secreted by the adenohypophysis signal in puberty
In the female, what is puberty marked by?
onset of menstruation
How long is the menstrual cycle?
28 days
What 3 signs are given that signal functional maturity of the female reproductive organs in the first menstrual cycle?
- release of mature oocyte
- Providing a suitable environment for implantation
- producing steroid hormones
What produces the female germ cell?
ovaries
What is the main production site of estrogen and progesterone?
the ovary
What is the site of fertilization?
The uterine tube
[fallopian tube/oviduct—>passageway for transfer of the oocyte]
Where is the site of implantation for the the fertilized oocyte?
uterus
What is the lowest portion of the uterus called?
cervix
Are the mammary glands closely related in physiology and function with the cycle changes of the female reproductive tract?
Yes
Are the ovaries covered in peritoneum?>
yes
What are the ovaries held in position by? Where is the blood supply carried in?
- ovarian ligament and suspensory ligament
2. suspensory ligament
What are the 4 histological components of the ovary?
- germinal epithelium
- tunica albuginea
- cortex
- medulla
The germinal epithelium is composed of what tissue type?
simple squamous to cuboidal
What is the dense connective tissue capsule below the germinal epithelium in the ovary?
Tunica Albuginea
What ovary portion contains the many follicles?
cortex
What is the innermost layer of the ovary? what type of CT?
medulla, loose connective tissues [and blood vessels from suspensory log]
What are the 4 functions of the ovary?
- oogenesis
- follicular development
- Ovulation
- steroidogenesis
When does production of the female gametes begin?
in the 1st month of embryonic life
Primordial germ cells migrate from the _______ into gonadal ridges that develop along the intermediate mesoderm to form _______ in the primitive gonads?
yolk sac,
sex cords
The primitive gonads are associated with what primitive duct?
mesonephric duct
[and alongside it the paramesonephric ducts]
The sex cords form clusters within the primitive gonad and each germ cell is surrounded by what to form what?
surrounded by follicular epithelium to create a primordial follicle
[there are more than 7 million oogonia in the developing ovary at 20 weeks]
As the ovary descends and the mesonephric ducts degenerate…what forms the uterine tube and uterine canal?
paramesonephric duct
At what meiosis phase are oogonia halted at?what are they called? How long do they remain here?
prophase I— primary oocytes—until puberty
Are primary oocytes gradually lost? what is this called?
Yes
Atresia
Where are ovarian follicles found? and what do they contain
ovarian cortex
-an oocyte surrounded by follicular epithelial cells
What is the development of ovarian follicles regulated by? what triggers ovulation?
follicle stimulating hormone triggers a number of primary oocytes to re-commence meiosis[adenohypophysis]
Luteinizing hormone [day 14]
What are the 2 types of primary follicle?
early stage unilaminar
and late stage multilaminar
What are the characteristics of unilaminar primary follicle?
- simple cuboidal follicular cells
- zona pellucid between oocyte and follicular cells
- primary oocyte is arrested in prophase I
What are the characteristics of the multi laminar oocyte?
- follicular cells form stratified cuboidal layer called stratum granulosum
- CT organize around and form theca follicle
- primary oocyte is arrested in prophase I
What are the characteristics of primordial follicles?
single squamous layer surrounding oocyte and arrested in prophase I
The secondary follicle is characterized by what?
development of an antrum in the stratum granulosum filled with liquor folliculi
What does the theca follicle differentiate into in the secondary follicle?
theca interna and theca externa
What is the theca interna composed of?
endocrine cells that produce androstenedione in response to LH
What is androstenedione
male sex hormone converted to estradiol by cells in the zone granulosum
What does estradiol do to follicle?
causes zona granulosa to proliferate
What is the theca extern composed of
mainly CT and smooth muscle