Pacemaking Flashcards

1
Q

Begin fase 4 van pacemaker cel

A

funny current (If) = mix van binnenwaartse Na stroom en buitenwaartse K stroom (Na overheerst)

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2
Q

Halverwege fase 4 van pacemaker cel

A

kortdurende transient Ca stroom (Ica)

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3
Q

Eind fase 4 van pacemaker cel

A

langdurende Ca stroom

brengt pacemakercel tot depolarisatiedrempel

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4
Q

Fase 0 van pacemaker cel

A

geen Na betrokken

depolarisatie door Ica(L)

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5
Q

Fase 2 van pacemaker cel

A

ontbreekt

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6
Q

Fase 3 van pacemakercel

A

repolarisatie door Ik

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7
Q

sympathische invloed

A

stimulatie van B-adrenerge receptoren door adrenaline bevordert de inwaartse stroom van If en Ica waardoor de pacemaking snelheid toeneemt
steilere fase 4
hier grijpen Beta Blockers in

door: depolarisatie sneller laten verlopen OF threshold verlagen

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8
Q

parasympathische invloed (vagale)

A

stimulatie van muscarine (M2)- receptoren door acetylcholine bevordert de uitwaartse K stroom waardoor de palingsnelheid afneemt
vlakkere fase 4

door: depolarisatie minder snel laten verlopen OF maximale diastolisch potentiaal verlagen OF threshold verhogen

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9
Q

mitralis klep

A

tussen LA en LV

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10
Q

tricuspidalis klep

A

tussen RA en RV

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11
Q

chordae tendinae

A

bevestigen AV kleppen aan de pappilair spieren

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12
Q

I-band

A

actine
licht
kleiner bij contractie

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13
Q

H-band

A

myosine
donker
kleiner bij contractie

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14
Q

A-band

A

myosine en actine
donker
even groot bij contractie

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15
Q

M-lijn

A

bevestigt myosine

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16
Q

Z-lijn

A

bevestigt actine