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Top 200 Drugs > P2 Fall Exam 2: Lipids/Cardio > Flashcards

P2 Fall Exam 2: Lipids/Cardio Flashcards

1
Q

amiodarone: brand

A

Cordarone, Pacerone

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2
Q

amiodarone: dosage form

A

tablet, INJ

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3
Q

amiodarone: indication

A

ventricular arrhythmia

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4
Q

amiodarone: efficacy

A

ECG
HR & symptomatic improvement if used for rate control

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5
Q

rivaroxaban: brand

A

Xarelto

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6
Q

Rivaroxaban: dosage form

A

tablet

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7
Q

rivaroxaban: FDA indication

A
  1. prevention of thromboembolism, after orthopedic surgery
  2. prevention of thromboembolism, w/ nonvalvular AFib
  3. Tx & secondary prevention of DVT or pulmonary embolism
  4. Coronary artery disease (stable) or peripheral artery disease
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8
Q

rivaroxaban: efficacy

A

-prevention of clotting or recurrence of clotting
-routine monitoring of anticoag tests is not necessary
-if used, anti-Xa activity is the preferred test

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9
Q

warfarin: brand

A

Coumadin, Jantoven

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10
Q

warfarin: dosage form

A

tablet, INJ

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11
Q

warfarin: FDA indication

A

Multiple!!
1. AFib
2. MI
3. prosthetic cardiac valve comp. embolism
4. pulmonary embolism
5. thrombosis, post MI
6. venous thromboembolism

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12
Q

Warfarin: efficacy

A

Measure initial INR after first 2-3 doses & subsequently at intervals no longer than every 4 wk
once stable dose achieved, may monitor 12 wk in stable pt
Pt at high risk of bleeding require more frequent monitoring
INR target and therapeutic range depend on indication: AFib/AFlutter target: 2.5 (range 2-3), prosthetic heart valves: 2.5 (range 2-3), mechanical mitral or aortic valve: 3 (range 2.5-3.5), MI & ST elevation: 3 (range 2.5-3.5 w/ aspirin), venous thromboembolism, prophylaxis, & tx (including pulmonary embolism, DVT, hip/knee arthroplasty: 2.5 (range 2-3).

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13
Q

arrhythmia

A

Amiodarone, Digoxin

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14
Q

thromboembolism

A

rivaroxaban, warfarin

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15
Q

pulmonary embolism

A

rivaroxaban, warfarin, Apixaban

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16
Q

artery disease

A

rivaroxaban

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17
Q

AFib

A

Warfarin, Apixaban, Digoxin

18
Q

MI

A

Warfarin, Clopidogrel

19
Q

HF

A

digoxin

20
Q

Cobalamin deficiency

A

Cyanocobalamin

21
Q

angina

A

isosorbide mononitrate, nitroglycerin

22
Q

anal fissure

A

Nitroglycerin

23
Q

thrombosis

A

clopidogrel, Warfarin, Apixaban (DVT)

24
Q

hyperlipidemia

A

Gemfibrozil, Fenofibrate, Ezetimibe, Atorvastatin, Pravastatin, Rosuvastatin, Simvastatin
(Gem + Fen + Eze + Statins (-Lova))

25
Q

hyperlipoproteinemia

A

Gemfibrozil

26
Q

hypercholesterolemia

A

Fenofibrate, Ezetimibe, Atorvastatin, Lovastatin, Pravastatin, Rosuvastatin, Simvastatin
(No Gem)

27
Q

ASCVD

A

Atorvastatin, Simvastatin

28
Q

prevention of CV events

A

Atorvastatin, Simvastatin

29
Q

Cerebrovascular accident

A

Pravastatin

30
Q

Digoxin indications

A

AFib, HF, arrhythmia

31
Q

Digoxin efficacy

A

ECG, decreased HR, improve symp of HF
0.8-2 ng/ml for AFIB
<1 for HF

32
Q

efficacy: cyanocobalamin

A

B12 & folic acid levels
intrinsic factor
normalization: MCV, Hgb
resolution of symptoms of anemia

33
Q

efficacy: Apixaban

A

absence of thrombosis, stroke
resolution of DVT or pulmonary embolism

34
Q

efficacy: isosorbide mononitrate

A

decrease use of SL nitro
reduction in angina episodes

35
Q

efficacy: Nitrogylcerin

A

decrease use of SL nitro
reduction in angina episodes & pain

36
Q

efficacy: Clopidogrel

A

reduction in thrombotic events

37
Q

efficacy: Gemfibrozil

A
  1. reduce Triglyceride levels
  2. reduce total cholesterol, LDL, increase HDL
    monitor baseline q 6 mo
38
Q

efficacy: Fenofibrate

A

reduce: total cholesterol, LDL, triglycerides
increase: HDL

39
Q

efficacy: Pravastatin

A

baseline fasting lipid panel, repeat 4-12 wk after initiation or dose adj.

40
Q

efficacy: Simvastatin

A

fasting lipid panel 4-12 after start of therapy and every 3-12 mo thereafter

Top 200 Drugs (8 decks)

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