Oxymatazoline HCI [Afrin Nasal Spray]

Question 1

What is the drug class for Oxymatazoline HCl [Afrin Nasal Spray]?

Answer 1

Nasal Spray: Decongestant

Question 2

What is the MOA for Oxymatazoline HCl [Afrin Nasal Spray]?

Answer 2

Vasoconstriction (direct-acting alpha agonist)

Question 3

What are the indications for Oxymatazoline HCl [Afrin Nasal Spray]?

Answer 3

SHORT TERM! nasal decongestion (3 days maximum)

Question 4

What are the common side effects/ADRs for Oxymatazoline HCl [Afrin Nasal Spray]?

Answer 4

Rebound mucosal congestion & vascular irritation, stinging, burning, dryness, sneezing; hypertension in large dose; epistaxis, tachyphylaxis

Question 5

What are the contraindications for Oxymatazoline HCl [Afrin Nasal Spray]?

Answer 5

Continuous use, glaucoma

Question 6

What are the common drug interactions for Oxymatazoline HCl [Afrin Nasal Spray]?

Answer 6

Alfa blockers, ergot derivatives

Question 7

How should you monitor Oxymatazoline HCl [Afrin Nasal Spray] ?

Answer 7

Length of use

Question 8

What are additional comments regarding Oxymatazoline HCl [Afrin Nasal Spray]?

Answer 8

Can be used twice daily for max 3 - 5 days as bridge to nasal steroid spray; rhinitis medicamentosa management - try steroid nasal spray; doesn’t relieve itching of allergic rhinitis; sinusitis, acute ETD in adults; avoid continuous oral use of decongestants (pseudoephedrine or phenylephrine)