Fexophenadine HCl [Allegra]

Question 1

What is the drug class for Fexophenadine HCl [Allegra]?

Answer 1

Antihistamine 2nd Generation: Oral

Question 2

What is the MOA for Fexophenadine HCl [Allegra]?

Answer 2

H1 receptor blocker

Question 3

What are the indications for Fexophenadine HCl [Allegra]?

Answer 3

Allergic rhinitis

Question 4

What are the common side effects/ADRs for Fexophenadine HCl [Allegra]?

Answer 4

Headache, somnolence (sleepiness), dizziness; increases any anticholinergic effect of other co-administered drugs

Question 5

What are the contraindications for Fexophenadine HCl [Allegra]?

Answer 5

Hypersensitivity; caution in asthma, prostatic hypertrophy, angle-closure glaucoma, dementia

Question 6

What are the common drug interactions for Fexophenadine HCl [Allegra]?

Answer 6

Verapamil (incr fexophenodine conc]; diminishes the impact of acetylcholinesterase inhibitors in dementia

Question 7

How should you monitor Fexophenadine HCl [Allegra]?

Answer 7

Symptom improvement; anticholinergic impact

Question 8

What are additional comments regarding Fexophenadine HCl [Allegra]?

Answer 8

Not sedating but not as effective as nasal corticosteroids; does not cross the BBB to any significant extent; PG C, Lact caution

Question 9

PG Status for Fexophenadine HCl [Allegra]?

Answer 9

PG C