Meclizine [Antivert]

Question 1

What is the drug class for Meclizine [Antivert]?

Answer 1

Anti-Vertigo Drug

Question 2

What is the MOA for Meclizine [Antivert]?

Answer 2

Anticholinergic impact on chemoreceptor trigger zone; blocks conduction in middle ear vestibular-cerebellar pathway

Question 3

What are the indications for Meclizine [Antivert]?

Answer 3

Prevent / treat vertigo, motion sickness

Question 4

What are the common side effects/ADRs for Meclizine [Antivert]?

Answer 4

Sedation, thickening bronchial secretions

Question 5

What are the contraindications for Meclizine [Antivert]?

Answer 5

Hypersensitivity; caution in asthma, prostatic hypertrophy, angle-closure glaucoma, dementia

Question 6

What are the common drug interactions for Meclizine [Antivert]?

Answer 6

Avoid ethanol, other anticholinergic medications

Question 7

How should you monitor Meclizine [Antivert]?

Answer 7

Effectiveness

Question 8

Additional comments regarding Meclizine [Antivert]?

Answer 8

Only “possibly effective”