Brimonidine [Alphagan P] Flashcards

1
Q

What is the drug class for Brimonidine [Alphagan P]?

A

Glaucoma: Alpha2 Agonist topical

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2
Q

What is the MOA for Brimonidine [Alphagan P]?

A

Selective agonism for alpha2-receptors causes reduced production of aqueous humor and increased outflow

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3
Q

What are the indications for Brimonidine [Alphagan P]?

A

Chronic open-angle glaucoma, ocular hypertension

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4
Q

What are the common side effects/ADRs for Brimonidine [Alphagan P]?

A

Somnolence, allergic conjunctivitis, hyperemia, eye pruritis, HTN, xerostomia, CNS depression

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5
Q

What are the contraindications for Brimonidine [Alphagan P]?

A

Children less than 2 years old

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6
Q

What are the common drug interactions for Brimonidine [Alphagan P]?

A

Other CNS depressants; Beta-blockers; MAO Inhibitors

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7
Q

How should you monitor Brimonidine [Alphagan P]?

A

IOP

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8
Q

Additional comments regarding Brimonidine [Alphagan P]?

A

benzalkonium chloride absorption by contact lens; t1/2 ~ 2H

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9
Q

PG Status for Brimonidine [Alphagan P]?

A

PG B

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10
Q
A
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