Brimonidine [Alphagan P] Flashcards
What is the drug class for Brimonidine [Alphagan P]?
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Glaucoma: Alpha2 Agonist topical
What is the MOA for Brimonidine [Alphagan P]?
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Selective agonism for alpha2-receptors causes reduced production of aqueous humor and increased outflow
What are the indications for Brimonidine [Alphagan P]?
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Chronic open-angle glaucoma, ocular hypertension
What are the common side effects/ADRs for Brimonidine [Alphagan P]?
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Somnolence, allergic conjunctivitis, hyperemia, eye pruritis, HTN, xerostomia, CNS depression
What are the contraindications for Brimonidine [Alphagan P]?
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Children less than 2 years old
What are the common drug interactions for Brimonidine [Alphagan P]?
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Other CNS depressants; Beta-blockers; MAO Inhibitors
How should you monitor Brimonidine [Alphagan P]?
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IOP
Additional comments regarding Brimonidine [Alphagan P]?
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benzalkonium chloride absorption by contact lens; t1/2 ~ 2H
PG Status for Brimonidine [Alphagan P]?
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PG B