oxazolidinones Flashcards

memorisation

1
Q

linezolid spectre

A

GISA
ERV
PRP (pneumocoque résistant à la pénicilline)

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2
Q

bacteries a resistence naturel et a quoi est due ce resistance

A

BGN due à un rejet à travers le porine TolC de la pompe à efflux ACrAB.

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3
Q

effet indesirable de linezolid a long terme d’administration

A

Toxicité neurologique —> hospitaliers

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4
Q

tedizolid spectre

A

cocci gram +
entero , staph ,strep

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5
Q

divers type resistance acquis

A

– Mutation au niveau ARNr23 s.
-mutation au niveau (L3,L4)
-gene de resistence cfr chloramphenicol-florfenicol.
(ce dernier est associee a un transposon , sur un plasmide)

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6
Q

les espece ayant cfr et a quoi sont t’ils resistant

A

staph, entero
aux oxalidinones
aux phenicole
aux lincosamide
sA
macrolide a 16 atomes

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