Overview metabolism Flashcards
not an essential nutrient?
carbohydrates
cells are system in what state?
dynamic steady state
“constant flux of nutrient”
alanine + amino acid is simply what?
pyruvate
unit of energy?
ATP
___is the common redox agent/electron carrier
NAD(P)H
NADH carries e- from breakdown (catabolism) ->ETC
NADPH carries e- for biosynthesis
biosynthesis and degradation pathway are?
distinct
= bank account, long terms storage of money to busy E
store fat
=money in your wallet to buy E immediately
Glycogen
this is the fast, high E stroage fuel in the cell
ATP (GTP etc)
ATP (GTP) different forms?
glutathione, BH4, Cytochrome c, NADH, NADPH
sources of electrons =
reducing power
pyruvate is decarboxylated to acetyl CoA is what kind of reaction?
Irreversible commitment
(you already have given up CO2)
3 carbon decarboxylated and no way to go back**
which molecule sits at a major branch point in central metabolism, leading to multiple possible pathway?
Glucose 6- phosphate
metabolism, always consider what states? (first one)
Fed, fasting, starvation states
metabolism, second thing to consider?
which tissues are we talking about
each tissue has fundamental differences in metabolism
metabolism is about moving electrons from __ to ____
from high to low potential
to build things, requires energy input
there are no specifically ____ individual sugars
essential
most oxidized form
CO2
most reduced form
methane methyl
proteins/amino acids are all about
Nitrogen N triplebonded N (covalent bond)
essential amino acids
you cannot synthesize them
what amino acids are conditionally essential?
tyrosine, cysteine, arginine
fats in diet are primarily in the form of fatty acid linked to the 3 carbon sugar/alcohol GLYCEROL, called__?
Triacylglycerols (handy storage form)
sugar alcohol, most sugar has double bonded to somewhere..glycerol has 3 OH “handy tool” can form/bond with water
Basal Metabolic Rate + Physical Activity + diet-induced thermogenesis
DEE
takes E and import/ship around the body and store
comb of all different things
calc. at rest( asleep )
Basal Metabolic Rate (BMR)
calc. at rest (awake). this often used interchangeably
While Resting Metabolic Rate (RMR)
FFM (fat free mass) is what?
Rough estimate of MBR - primary determinant of metabolism
a major reason to revamp the old pyramid was to include what?
exercies (symbolized by the staris)
BMI
Weight/height^2 (kg/m^2)
Ibs x 704/ height^2 (in^2)
obses range
more than 30
desirable range
18.5 - 24.9
vit D deficiencies
rickets
vit A deficiencies
xerophtalamia
estimates of nutriet intake for various groups (age, gender)
DRI
Dietary reference intakes
RDA
recommended dietary allowance
EAR (estimated average requirement)
amount of X required by 50% of any target group
RDA (recomm daily allowance)
EAR + 2SD (stn deviation)
adequate intake
we are completely sure
AL when lack data
Tolerable Upper intake level
taking too much vitamin
UL
when you don’t have glucose, what increase?
ketone body