Overdose Treatment Flashcards
What should be checked first for recommendations about treating an overdose?
TOXBASE
Also has contact number for advice
What can be given first line to reduce absorption of many substances?
Activated charcoal
Within 1 hour
What do you give for aspirin overdose?
Activated charcoal
Bicarbonate IV
Haemodialysis if severe
What do you give for paracetamol overdose?
N-Acetylcysteine
What do you give for overdose of opioids?
Naloxone
What do you give for overdose of Benzodiazepines?
Flumazenil
What do you give for overdose of beta blockers?
Glucagon for heart failure or cardiogenic shock
Atropine for bradycardia
What do you give for overdose of of CCBs?
Calcium chloride
or
Calcium gluconate
What do you give for overdose of cocaine?
Diazepam
What do you give for overdose of cyanide?
Dicobalt edetate
What do you give for overdose of methanol or ethylene glycol?
Fomepizole
or
Ethanol
What do you give for overdose of carbon monoxide?
100% oxygen
Hyperbaric chamber
What are some examples of substances which contain methanol?
Solvents or fuels
What contains ethylene glycol?
Antifreeze
What are the symptoms of paracetamol OD?
Abdominal pain
Nausea + vomiting
Jaundice
Loss of co-ordination
Hypoglycaemia
Seizures
What are the symptoms of aspirin OD?
Sweating
Tachypnoea and deep breathing
Tinnitus
Temporary hearing loss
What are the symptoms of TCA OD?
Excitability
Dry mouth
Large pupils
Irregular heart rhythm or tachycardia
Hypotension
Why do you get hypotension in TCA OD?
TCAs cause myocardial sodium channel blockade resulting in hypotension and arrhythmia
What are the symptoms of SSRIs OD?
Agitation
Tremor
Nystagmus
Severe muscle tension
What are the symptoms of beta blocker OD?
Hypotension
Bradycardia
What are the symptoms of CCB OD?
Agitation
Hypotension
Chest pain
Bradycardia
What are the symptoms of benzodiazepines OD?
Co-ordination and speech difficulty
Nystagmus
Shallow breathing
Drowsiness
What are the symptoms of opioid OD?
Miosis
Respiratory depression
Shallow breathing
Drowsiness
What are the symptoms of cannabis OD?
Paranoia
Hallucinations
Numbness in arms and legs
What are the symptoms of stimulant OD?
Anxiety and paranoia
Agitation
Hallucinations
High temperature
Chest pain
Tachypnoea
Irregular or fast heartbeat