Overdose

Question 1

Aspirin
- […]
- Respiratory […] (early)
- Metabolic […] (late)

Mx:
1. Activated charcoal if <[…]hr
2. IV fluid, […] […] –> alkalise urine
3. If too high –> […]

Monitor complications
- Pulmonary […]
- Renal function

Answer 1

Tinnitus
alkalosis
acidosis

1
sodium bicarbonate
dialysis

oedema

Question 2

TCA
- […], coma, […] and cardiac dysrhythmia + […] PUPILS

Invx - look for […]
ECG - may be […] […]

Mx - IV […]

Answer 2

drowsiness, seizures, DILATED

acidosis, prolonged QT

bicarbonate

Question 3

Paracetamol

Can present […] or with […] dysfunction (buildup of […] after […] depletion)

Mx
<[…]hr –> activated charcoal
Staggered or unsure when, or >[…]hr –> N-acetyl cysteine
<4hr –> take level at […]hr and check nomogram’
[…]-[…]hr - take level and treat with nomogram

NAC assoc with […] reaction (not IgE mediated) –> antihistamine (not adrenaline)

Answer 3

asymptomatic, liver, NAPQI, glutathione

1
15
4
4-15

anaphylactoid

Question 4

Opioid

Answer 4

Constricted pupils + respiratory depression

Mx: naloxone