Ovarian Cancer Flashcards
What type of cysts can arise in the ovary?
Follicular Luteal Endometriotic Epithelial Mesothelial
Where can endometriosis arise?
Ovary Pouch of Douglas Peritoneal surfaces including uterus Cervix, vulva, vagina Bladder, bowel
Complications of endometriosis? (5)
Cyst formation Adhesions Infertility Ectopic pregnancy Malignancy - endometrioid carcinoma
What are the types of ovarian tumours? (5)
Epithelial Germ cell Sex-cord/ stromal Metastatic Miscellaneous
What are the 6 types of epithelial ovarian tumours?
Serous Mucinous Endometrioid Clear cell Brenner Undifferentiated
What is meant by a ‘malignant’ epithelial ovarian tumour?
Stromal invasion
What are the 2 types of serous ovarian tumours?
High grade - serous tubal intraepithelial carcinoma (STIC)
Low grade - serous borderline tumour
What is a Brenner ovarian tumour?
Tumour of transitional epithelium
Usually benign
What are the types of germ cell ovarian tumours?
Teratoma = dermoid cyst Immature teratoma Dysgerminoma Yolk sac tumour Choriocarcinoma Embryonal carcinoma Mixed germ cell tumour
What is the most common malignant primitive germ cell tumour?
Dysgerminoma
Who gets dysgerminomas?
Children and young women
Av age 22 yrs
What are the types of sex cord/ stromal ovarian tumours?
Fibroma/ Thecomaa
Granulosa cell tumour
Sertoli-Leydig tumours
What might a fibroma/ thecoma produce?
Oestrogen
Causing uterine bleeding
What might a sertoli-leydig tumour produce?
Androgens
What are common sites that metastasise to ovary?
Stomach
Colon
Breast
Pancreas
