Ovarian cancer Flashcards
what is the most important independent risk factor for ovarian cancer? what are other risk factors?
- age
- family history
- BRCA-1
- nulliparity, infertility, endometriosis
is CA-125 a good screening technique for ovarian cancer?
no
is an adnexal mass in young women often benign or malignant? what does it usually consist of?
- benign
- functional cyst
what is the workup for an adnexal mass? what needs to be considered?
- BHCG
- transvaginal US
consider timing in cycle
what should be excluded in the workup for an adnexal mass in a postmenopausal woman? what exams should you do?
- endometriosis
- cyst
- abscess
- breast exam
- DRE
- mammography
what is the positive predictive value of US for adnexal masses?
low
what is the epithelial tumor marker?
CA-125
what are the malignant germ cell tumor markers?
- BHCG
- LDH
- AFP
what are the embryonal tumor markers?
- AFP
- BHCG
what is the endodermal sinus tumor marker?
AFP
what is the granulosa cell tumor marker?
inhibin
what are the treatment options for epithelial ovarian cancer?
- cytoreductive surgery
- chemo
what is the most lethal gynecological malignancy?
ovarian cancer
what are the presenting symptoms of a molar pregnancy?
- first trimester bleeding with size > menstrual dates
- elevated BHCG
- toxemia prior to 24 weeks gestation
- hyperemesis
what is the imaging modality of choice for gestational trophoblastic disease?
US
