ovarian Flashcards

1
Q

different type sof cells in ovary

A

epithelial, germ cells + sex cord - which

may give rise to benign or malignant tumors

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2
Q

what is most likley to be the sign of ovarian tumour

A

chronic pelvic pain or ntoicing a mass , or even dysparenia and a feeling of pressure in the pelvis

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3
Q

examples of non functional cytss

A

endometriosis, dermoid cysts, cystadenomas, +

malignant cysts

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4
Q

functional cyst features

A

rarely grows >10 cm

us- unilocular

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5
Q

which types of cysts are common in perimenopausal wormn

A

epithelial cysts

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6
Q

examples of epithelias cysts

A

cystadenomas, brenner tumor, seroud, papillary

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7
Q

sex cord tumours are usually seen in

A

elderly women

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8
Q

seorus vs mucinous cystandenomas

A

serous - more likely to be bilateral

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9
Q

what is thecoma

A

Estrogen secreting tumors – post menopausal bleeding

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10
Q

examples of sex cords

A

fibroma and thecoma , granulosos , sertoli leydig (which the last 2 are more commonly seen in testicular cancers)

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11
Q

examples of germ cells

A

dysgerminoma, yolk sac,choriocarcinoma , tertatoma

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12
Q

which tumours are of premenoupasual women

A

GERM CELL vs epithela (post menopausal)

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13
Q

which type of cancer is more assoiated with PCOS

A

endometerial cancer

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14
Q

prtective factors to ovarian cancer

A

being ont he oral contraceptives

prophylactic oophorectomy - (but there is still a chance you can devleop it)

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15
Q

RF ovarian caner

A

neevr having kids before
family histoty
pcos?
BRAC 1 BRAC 2

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16
Q

GERM CELL TUMOUR FEATURES

A

Originate from the germ cells in the embryonic gonad.

These tumours typically grow rapidly and spread predominantly via the lymphatic route.

Germ cell tumours most commonly arise in young women, which is atypical for most cases of ovarian cancer.

Tumour markers include alpha-fetoprotein and sometimes beta human chorionic gonadotrophin (B-HCG).

17
Q

Sex cord stromal tumours features

A

Originate from connective tissue.

They are rare, making up less than 5% of all ovarian tumours. They are malignant tumours, but are much less aggressive than epithelial tumours.

Additionally, ovarian cancer can be secondary to another cancer elsewhere, which has metastasised to the ovary. A Krukenberg tumour refers to a “signet ring” sub-type of tumour, typically gastrointestinal in origin, which has metastasised to the ovary.

18
Q

THE GREAT

A

the greater the number of ovulations - early menarche and latemenopuase
family history
null parity

19
Q

2 main markers used

A

CA- 124

HE4

20
Q

bad signs on US

A
size >5 cm 
irregular 
mutichamberes 
bilateral 
ascites
21
Q

meigns syndrome

A

the triad of benign ovarian tumor with ascites and pleural effusion that resolves after resection of the tumor. Ovarian fibromas constitute the majority of the benign tumors seen in Meigs syndrome

22
Q

theca luteal cyst

A

bilateral cysts usallya nd as as a result of excess B-hcg levels