Other hormones II Flashcards

1
Q

Terazosin

A

alpha (1) blocker - for BPH and HTN

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2
Q

Estradiol hemihydrate 10mcg/day

A

Vaginal tablet

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3
Q

Testosterone propionate

A

FDA approved androgen

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4
Q

Paroxetine mesylate

A

SSRI - 1st non-hormal agent for mod-severe hit flashes/night sweats

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5
Q

Ospemifene

A

(PO) SERM - Vaginal atrophy Dyspareunia

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6
Q

Testosterone enanthate

A

FDA-approved (IM) long acting androgen -Carcinoma of breast

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7
Q

Clomiphene

A

(PO) Ovulation-inducing agent

no more than 3 courses (5d)

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8
Q

Raloxifene

A

(PO) SERM - PVT/TXT - FOR osteoporosis!!!

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9
Q

Avanafil

A

PDE5 inhibitor - ED

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10
Q

Testosterone transdermal system

A

Short acting androgen-do NOT apply to balls and/or dick

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11
Q

Alfuzosin

A

alpha (1) blocker - Only for BPH

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12
Q

Testosterone pellets

A

(SQ) Implant -Replace therapy

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13
Q

Medroxyprogesterone acetate

A

(IM) - Progestin - non-hysterectomized post menopausal women receiving estrogen tablets

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14
Q

Finasteride (proscar)

A

5alpha reductase inhibitor - BPH (stops/reduces size)

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15
Q

Tamoxifen

A

(PO) SERM - PVT/TXT breast cancer

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16
Q

Yohimbine HCL

A

Herbal - A2-BLK - Non-FDA approved for ED

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17
Q

Transdermal gels and solutions

A

Short acting androgen-do NOT apply to balls and/or dick

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18
Q

Conjugated Estrogens/Bazedoxifene

A

SERM/Estg combo
Reduces risk of endometriosis
-can cause cancer/GB DZ

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19
Q

Estropipate

A

(PO) Estrogen Products

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20
Q

Norethindrone

A

(PO) - Progestin

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21
Q

Alprostadil

A

PGE1 - Needle to the dick - V-dil via smooth Msc relax

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22
Q

Sildenafil

A

PDE5 inhibitor - ED + Pulm Arterial HTN

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23
Q

Vaginal estrogen products

A

Cream, rings, Tablet - treat local symptoms for Vag atrophy

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24
Q

Exemestane

A

Aromatase inhibitors - TXT estrg dependent tit cancer

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25
Conjugated estrogens
(PO) Estrogen Products, vaginal creams, combo hormone products
26
Esterified estrogens
Oral Estrogen Products
27
17 B-Estradiol
Oral Estrogen Products, vaginal ring, transdermal
28
Micronized estradiol
Vaginal Creams
29
Fluoxymesterone
FDA approved androgen
30
Levonorgestrel Intrauterine system
Progestin product
31
Vardenafil
PDE5 inhibitor - ED
32
Estradiol acetate
Vaginal Rings
33
Norethindrone acetate
(PO) - Progestin products 2nd amenorrhea, endometriosis, uterine bleeding
34
Mifeprostone (Korlym)
Prog antagonist - Hyperglycemia w/ cushing syndrome
35
Methyl testosterone
FDA approved androgen, treats breast cancer, post-pubertal cryptochordism
36
Tamsulosin
alpha (1a) Blk -
37
Doxazosin
alpha (1) blocker - for BPH and HTN
38
Micronized progesterone
PVT endometrial hyperplasia
39
Letrozole
Aromatase inhibitors - TXT estrg dependent tit cancer
40
Black Cohosh
Herbal - Reduce hot flashes - increases breast density
41
Testosterone cypionate (oil)
(IM) long acting androgen -Replace therapy, carcinoma of the breast
42
Depo-testosterone
(IM) long acting androgen -deficiency replacement therapy
43
Tadalafil
PDE5 inhibitor - BPH
44
Megestrol acetate
(PO)-Progestin- appetite stim- TXT Metastatic breat cancer
45
Progesterone gel
Infertile women with progesterone defecit
46
Mifeprostone (Mifeprex)
Prog antagonist - stop intrauterine preg up to 70D
47
Danazol
Androgen derivative - endometriosis/fibrocystic breast DZ
48
Finasteride (propecia)
5alpha reductase inhibitor - male pattern baldness
49
Conjugated estrogens
Vaginal Creams
50
Red Clover
Herbal - Reduce freq of hot flash
51
Anastrozole
Aromatase inhibitors - TXT estrg dependent breast cancer
52
Flibanserin
Serotonin/dopamine activity - premeno w/ sex desire D/O
53
17B - Estradiol transdermal forms
Matrix patch, gel, spray - Mod-severe menoP
54
Synthetic conjugated estrogens B
PO - Estrogen Products
55
Synthetic conjugated estrogens A
PO - Estrogen Products
56
What causes genitourinary atrophy?
Decreased Estrogen
57
Whats a key point when using MHT concerning dose/duration?
Lowest dose for shortest time
58
If patient has intact uterus what should be recommended?
Adding progestin to MHT
59
MHT using which progestin?
Medroxyprogesterone
60
What is a long term risk of hormonal replacement?
Cancer
61
What factors in the coag cascade does estrg increase?
7 and 12
62
What is consider a short duration on MHT?
<2-3yr but no more than 5yr
63
If there has been a hysterectomy which hormone should be used?
Conjugated Estrogen
64
For genital atrophy w/out other s/s what should be used first?
Vaginal preperation then (PO) hormones
65
Whats the Estg - cyclic prog plan consist of?
``` Continued Estrogen Cyclic therapy of Estg 1-25d Medprog 14-25D Stop both 26D to end of month ```
66
What does Estg and continued prog plan consist of?
Cont Esgt and cont prog daily w/out break
67
What does intermittent cycle consist of
Cont Estg | Prog 3D on - 3D off
68
Esterfied estrogen
(PO) estrogen
69
Whats the indications for using vaginal estrogen?
Atrophic vaginitis
70
Whats the indications for using transdermal estrogen?
Mod-severe S/S due to menopause
71
What drugs are combo with 17B - estradiol?
Drospironeone Levonorgestrel Norethindrone acetate (patch)
72
what drugs are comboed with Conjugated estrogen?
Medroxyprogesterone acetate Medroxyprogesterone Bazedoxifene
73
When MHT not recommended what is DOC for vasomotor s/s in risk women?
SSRI - Parxetine Mesylate
74
What are the SERMS used in menopause?
R-Raloxifene - OP O-Ospermifene - Mod-sev vaginal atrophy T-Tamoxifene - Breast cancer PVT/TXT