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Junior Pharm II > Other hormones II > Flashcards

Other hormones II Flashcards

1
Q

Terazosin

A

alpha (1) blocker - for BPH and HTN

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2
Q

Estradiol hemihydrate 10mcg/day

A

Vaginal tablet

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3
Q

Testosterone propionate

A

FDA approved androgen

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4
Q

Paroxetine mesylate

A

SSRI - 1st non-hormal agent for mod-severe hit flashes/night sweats

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5
Q

Ospemifene

A

(PO) SERM - Vaginal atrophy Dyspareunia

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6
Q

Testosterone enanthate

A

FDA-approved (IM) long acting androgen -Carcinoma of breast

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7
Q

Clomiphene

A

(PO) Ovulation-inducing agent

no more than 3 courses (5d)

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8
Q

Raloxifene

A

(PO) SERM - PVT/TXT - FOR osteoporosis!!!

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9
Q

Avanafil

A

PDE5 inhibitor - ED

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10
Q

Testosterone transdermal system

A

Short acting androgen-do NOT apply to balls and/or dick

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11
Q

Alfuzosin

A

alpha (1) blocker - Only for BPH

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12
Q

Testosterone pellets

A

(SQ) Implant -Replace therapy

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13
Q

Medroxyprogesterone acetate

A

(IM) - Progestin - non-hysterectomized post menopausal women receiving estrogen tablets

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14
Q

Finasteride (proscar)

A

5alpha reductase inhibitor - BPH (stops/reduces size)

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15
Q

Tamoxifen

A

(PO) SERM - PVT/TXT breast cancer

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16
Q

Yohimbine HCL

A

Herbal - A2-BLK - Non-FDA approved for ED

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17
Q

Transdermal gels and solutions

A

Short acting androgen-do NOT apply to balls and/or dick

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18
Q

Conjugated Estrogens/Bazedoxifene

A

SERM/Estg combo
Reduces risk of endometriosis
-can cause cancer/GB DZ

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19
Q

Estropipate

A

(PO) Estrogen Products

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20
Q

Norethindrone

A

(PO) - Progestin

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21
Q

Alprostadil

A

PGE1 - Needle to the dick - V-dil via smooth Msc relax

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22
Q

Sildenafil

A

PDE5 inhibitor - ED + Pulm Arterial HTN

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23
Q

Vaginal estrogen products

A

Cream, rings, Tablet - treat local symptoms for Vag atrophy

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24
Q

Exemestane

A

Aromatase inhibitors - TXT estrg dependent tit cancer

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25
Q

Conjugated estrogens

A

(PO) Estrogen Products, vaginal creams, combo hormone products

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26
Q

Esterified estrogens

A

Oral Estrogen Products

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27
Q

17 B-Estradiol

A

Oral Estrogen Products, vaginal ring, transdermal

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28
Q

Micronized estradiol

A

Vaginal Creams

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29
Q

Fluoxymesterone

A

FDA approved androgen

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30
Q

Levonorgestrel Intrauterine system

A

Progestin product

31
Q

Vardenafil

A

PDE5 inhibitor - ED

32
Q

Estradiol acetate

A

Vaginal Rings

33
Q

Norethindrone acetate

A

(PO) - Progestin products
2nd amenorrhea,
endometriosis,
uterine bleeding

34
Q

Mifeprostone (Korlym)

A

Prog antagonist - Hyperglycemia w/ cushing syndrome

35
Q

Methyl testosterone

A

FDA approved androgen, treats breast cancer, post-pubertal cryptochordism

36
Q

Tamsulosin

A

alpha (1a) Blk -

37
Q

Doxazosin

A

alpha (1) blocker - for BPH and HTN

38
Q

Micronized progesterone

A

PVT endometrial hyperplasia

39
Q

Letrozole

A

Aromatase inhibitors - TXT estrg dependent tit cancer

40
Q

Black Cohosh

A

Herbal - Reduce hot flashes - increases breast density

41
Q

Testosterone cypionate (oil)

A

(IM) long acting androgen -Replace therapy, carcinoma of the breast

42
Q

Depo-testosterone

A

(IM) long acting androgen -deficiency replacement therapy

43
Q

Tadalafil

A

PDE5 inhibitor - BPH

44
Q

Megestrol acetate

A

(PO)-Progestin-
appetite stim-
TXT Metastatic breat cancer

45
Q

Progesterone gel

A

Infertile women with progesterone defecit

46
Q

Mifeprostone (Mifeprex)

A

Prog antagonist - stop intrauterine preg up to 70D

47
Q

Danazol

A

Androgen derivative - endometriosis/fibrocystic breast DZ

48
Q

Finasteride (propecia)

A

5alpha reductase inhibitor - male pattern baldness

49
Q

Conjugated estrogens

A

Vaginal Creams

50
Q

Red Clover

A

Herbal - Reduce freq of hot flash

51
Q

Anastrozole

A

Aromatase inhibitors - TXT estrg dependent breast cancer

52
Q

Flibanserin

A

Serotonin/dopamine activity - premeno w/ sex desire D/O

53
Q

17B - Estradiol transdermal forms

A

Matrix patch, gel, spray - Mod-severe menoP

54
Q

Synthetic conjugated estrogens B

A

PO - Estrogen Products

55
Q

Synthetic conjugated estrogens A

A

PO - Estrogen Products

56
Q

What causes genitourinary atrophy?

A

Decreased Estrogen

57
Q

Whats a key point when using MHT concerning dose/duration?

A

Lowest dose for shortest time

58
Q

If patient has intact uterus what should be recommended?

A

Adding progestin to MHT

59
Q

MHT using which progestin?

A

Medroxyprogesterone

60
Q

What is a long term risk of hormonal replacement?

A

Cancer

61
Q

What factors in the coag cascade does estrg increase?

A

7 and 12

62
Q

What is consider a short duration on MHT?

A

<2-3yr but no more than 5yr

63
Q

If there has been a hysterectomy which hormone should be used?

A

Conjugated Estrogen

64
Q

For genital atrophy w/out other s/s what should be used first?

A

Vaginal preperation then (PO) hormones

65
Q

Whats the Estg - cyclic prog plan consist of?

A 
Continued Estrogen
Cyclic therapy of
        Estg 1-25d
Medprog 14-25D
Stop both 26D to end of month
66
Q

What does Estg and continued prog plan consist of?

A

Cont Esgt and cont prog daily w/out break

67
Q

What does intermittent cycle consist of

A

Cont Estg

Prog 3D on - 3D off

68
Q

Esterfied estrogen

A

(PO) estrogen

69
Q

Whats the indications for using vaginal estrogen?

A

Atrophic vaginitis

70
Q

Whats the indications for using transdermal estrogen?

A

Mod-severe S/S due to menopause

71
Q

What drugs are combo with 17B - estradiol?

A

Drospironeone
Levonorgestrel
Norethindrone acetate (patch)

72
Q

what drugs are comboed with Conjugated estrogen?

A

Medroxyprogesterone acetate
Medroxyprogesterone
Bazedoxifene

73
Q

When MHT not recommended what is DOC for vasomotor s/s in risk women?

A

SSRI - Parxetine Mesylate

74
Q

What are the SERMS used in menopause?

A

R-Raloxifene - OP
O-Ospermifene - Mod-sev vaginal atrophy
T-Tamoxifene - Breast cancer PVT/TXT

Junior Pharm II (8 decks)

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