Allergies Flashcards

1
Q

Hydroxyzine

A

(PO) 1st Gen AH - Urticaria (hives) and itching

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2
Q

MOA - Synthetic A1 ag

A

PE

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3
Q

Loratidine w/PSE

A

AH - Decongestant combo - 2nd gen

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4
Q

Azelastine 0.05%

A

Ocular AH

Nonselect H1 receptor antag

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5
Q

MOA - Direct A>B ag - displaces NEPI

A

PSE

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6
Q

MOA - Inhibits mast cell degranulation of histamine/leukotrienes

A

Mast cell stabilizers

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7
Q

Ipratropium

A

(IN) Anticholinergic - Cat B - decreased nasal secretion

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8
Q

Oxymetazoline 0.025%

A

Long acting A1/A2 agonist (Visine LR)
Ocular Decon
Rebound hypermia
(IN - Afrin - v-con)

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9
Q

(PO)/(IN) AH best for?

A

itching and sneezing

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10
Q

Diphenhydramine

A

(PO) 1st Gen AH - Cat: B and OTC sleep aid

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11
Q

Levocabastine 0.05%

A

Ocular AH Nonselec H1 antag

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12
Q

Nedocromil 2%

A

Ocular Mast Cell Stablizers (2x/D)

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13
Q

Loratadine

A

(PO) 2nd Gen AH - AR - Nonsedating - Cat B

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14
Q

Higher bioavailabilityof INS is associated with?

A

Greater growth suppression effects

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15
Q

Carbinoxamine + PE

A

AH - Decon combos - 1st gen

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16
Q

Coricidin HBP

A

AH - Decon alternative - Cough and cold - High BP alt

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17
Q

Montelukast

A

Leukotriene Inhibitor - Cat B

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18
Q

Lodoxamide 0.1%

A

Ocular Mast Cell Stablizers – Prophylaxis

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19
Q

Fexofenadine w/ PSE

A

AH - Decongestant combo - 2nd gen

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20
Q

Cromolyn sodium (OTC)

A

(IN) Mast Cell Stablizer - DOC preggo w/ rhinorrhea/sneezing (3-4x/D)

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21
Q

Meclizine

A

(PO) 1st Gen AH - Vertigo

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22
Q

MOA - Inhibits mast cell inflammatory mediator cysteinyl leukotriene

A

Leukotriene receptor antag (LTRA)

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23
Q

Which (PO) AH has high Sedative/Anticholinergic effects?

A

Diphenhydramine

Promethazine

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24
Q

What allergy drugs can cause increased IOP

A

Non-selective Ocular AH
Decongestants (Any type)
Ocular steroids

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25
Q

Prochlorperazine

A

(PO) 1st Gen AH - N/V for preggo

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26
Q

Olopatadine 0.1% (Patanol)

A

Ocular 2nd gen AH
Selective H1 antag
Better than Ketotifen AH

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27
Q

What composes Coricidin HBP cough and cold?

A

Dextromethorphan

Chlorpheniramine

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28
Q

Cetirizine

A

(PO) 2nd Gen AH - AR - Nonsedating - Cat B

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29
Q

What steroid is considered soft or smart?

A

Ocular Loteprednol (low rate SEs)

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30
Q

Cyproheptadine

A

(PO) 1st Gen AH - For Serotonin Syndrome

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31
Q

Anticholinergics is best for?

A

Rhinorrhea

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32
Q

Cat B allergy drugs

A
Chlorpheniramine (Preferred AH)
Diphenhydramine 
Loratadine 
Cetirizine 
Budesibude (Perferred INS)
Montelukast (LTRA)
Ipratropium
Cromolyn Sodium (Mast cell stabilizer)
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33
Q

Pseudoephedrine (PSE)

A

(PO) Direct acting A>B agonist
(displaces NEPI)
Nasal Decon - DOC preggo 2nd tri or later

34
Q

Brompheniramine

A

(PO) 1st Gen AH

35
Q

Another name for Rebound congestion?

A

Rhinitis Medicamentosa

36
Q

What are the 2 (PO) decongestants

A

PE and PSE

37
Q

MOA - Muscarinic antag

A

Ipratropium

38
Q

Tetrahydrozoline 0.05%

A

Ocular Decongestants (Visine original)

39
Q

MOA - Direct A1/A2 ag

A

Oxymetazoline

40
Q

Conjunctivits commonly occurs with

A

Seasonal AR

41
Q

Cetirizine w/ PSE

A

AH - Decon combo - 2nd gen

42
Q

Cold compresses can effectively reduce what?

A

Ocular itching

43
Q

What are the different Visine?

A

Visine A - contains Naphazoline
Visine LR - Oxymetazoline 0.025%
Visine Original - Tetrahydrozoline 0.05%

44
Q

What is Oral burst therapy?

A

(PO) prednisone daily 5-7D for severe AR

45
Q

Azelastine HCL/Fluticasone Propionate

A

(IN) Steroid Combo - Seasonal AR for >6yo

46
Q

Beclomethasone

A

(IN) Steroids -Sig decrease growth velocity

47
Q

Chlorpheniramine

A

(PO) 1st Gen AH

Perferred AH for preggo

48
Q

Ketotifen 0.025%

A

Ocular AH 2nd gen Selective H1 antag - OTC

49
Q

What cells are concentrated in nose and conjunctiva?

A

Mast cells

50
Q

Fluticasone furoate

A

(IN) Steroids - low bioavail

51
Q

When does max effects of INS occur?

A

1-2wks

52
Q

Ketorolac

A

Ocular NSAID - for eye pain/discomfort

53
Q

Budesonide

A

(IN) Steroids - Preferred for pregnancy (B)

54
Q

Mometasone

A

(IN) Steroids - low sys bioavailability

55
Q

Phenylephrine

A

Synthetic A1 Agonist - increase BP -monitor

Eye redness, Nasal decon, Hemrrhoids

56
Q

MOA - decrease prostaglandin production

A

NSAID

57
Q

Conjunctivitis triad

A

Itching
Injection
Chemosis (edema)

58
Q

Levocetirizine

A

(PO) 2nd Gen AH - AR

59
Q

Triamcinolone

A

(IN) Steroids

60
Q

Fexofenadine

A

(PO) 2nd Gen AH - AR - Nonsedating

61
Q

MOA - Inhibits both early/late phase mediators

A

INS

62
Q

Cromolyn 4%

A

Ocular Mast Cell Stablizers Prophylaxis, combined w/ ocular AH

63
Q

Flunisolide

A

(IN) Steroids - Sig decrease growth velocity

64
Q

Which AH is more perferred, 1st Gen or 2nd Gen?

A

2nd Gen (less sedation/SEs)

65
Q

MOA - Competitive H1 antag or inverse ag

A

AH

66
Q

Fluticasone propioniate

A

(IN) Steroids - low sys bioavailability

67
Q

Intranasal Saline

A

Alternative - recommend to ALL pts

68
Q

What drug interations are asccociated with Decongestants?

A

MAOI w/in 2wks

69
Q

Azelastine (Nasal)

A

(IN) AH - AR - Crosses BBB

70
Q

Naphazoline 0.1%

A

Ocular Decon - most potent

71
Q

Olopatadine

A
2nd Gen (IN) AH-H1 Select - AR
Better than Azelastine AH
72
Q

What are the 2 (IN) decongestants

A

PE and oxymetazoline

73
Q

Which has more efficacy, (IN) AH or (PO) AH?

A

(IN) AH

74
Q

Brompheniramine + PE

A

AH - Decon combo - 1st gen

75
Q

Desloratadine

A

(PO) 2nd Gen AH - AR

76
Q

Chlorpheniramine w/PE

A

AH- Decon combo - 1st gen

77
Q

INS best for?

A

Everything to include eye S/S

78
Q

Promethazine

A

(PO) 1st Gen AH - For N/V Makes you sleepy

79
Q

Naphazoline 0.025% and Pheniramine 0.3%

A

Ocular AH and Decon Combo (Visine A)

80
Q

Loteprednol 0.2%

A

Ocular Steroids - Approved for seasonal allergic conjunctivitis