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Junior Pharm II > Allergies > Flashcards

Allergies Flashcards

1
Q

Hydroxyzine

A

(PO) 1st Gen AH - Urticaria (hives) and itching

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2
Q

MOA - Synthetic A1 ag

A

PE

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3
Q

Loratidine w/PSE

A

AH - Decongestant combo - 2nd gen

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4
Q

Azelastine 0.05%

A

Ocular AH

Nonselect H1 receptor antag

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5
Q

MOA - Direct A>B ag - displaces NEPI

A

PSE

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6
Q

MOA - Inhibits mast cell degranulation of histamine/leukotrienes

A

Mast cell stabilizers

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7
Q

Ipratropium

A

(IN) Anticholinergic - Cat B - decreased nasal secretion

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8
Q

Oxymetazoline 0.025%

A

Long acting A1/A2 agonist (Visine LR)
Ocular Decon
Rebound hypermia
(IN - Afrin - v-con)

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9
Q

(PO)/(IN) AH best for?

A

itching and sneezing

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10
Q

Diphenhydramine

A

(PO) 1st Gen AH - Cat: B and OTC sleep aid

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11
Q

Levocabastine 0.05%

A

Ocular AH Nonselec H1 antag

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12
Q

Nedocromil 2%

A

Ocular Mast Cell Stablizers (2x/D)

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13
Q

Loratadine

A

(PO) 2nd Gen AH - AR - Nonsedating - Cat B

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14
Q

Higher bioavailabilityof INS is associated with?

A

Greater growth suppression effects

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15
Q

Carbinoxamine + PE

A

AH - Decon combos - 1st gen

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16
Q

Coricidin HBP

A

AH - Decon alternative - Cough and cold - High BP alt

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17
Q

Montelukast

A

Leukotriene Inhibitor - Cat B

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18
Q

Lodoxamide 0.1%

A

Ocular Mast Cell Stablizers – Prophylaxis

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19
Q

Fexofenadine w/ PSE

A

AH - Decongestant combo - 2nd gen

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20
Q

Cromolyn sodium (OTC)

A

(IN) Mast Cell Stablizer - DOC preggo w/ rhinorrhea/sneezing (3-4x/D)

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21
Q

Meclizine

A

(PO) 1st Gen AH - Vertigo

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22
Q

MOA - Inhibits mast cell inflammatory mediator cysteinyl leukotriene

A

Leukotriene receptor antag (LTRA)

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23
Q

Which (PO) AH has high Sedative/Anticholinergic effects?

A

Diphenhydramine

Promethazine

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24
Q

What allergy drugs can cause increased IOP

A

Non-selective Ocular AH
Decongestants (Any type)
Ocular steroids

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25
Prochlorperazine
(PO) 1st Gen AH - N/V for preggo
26
Olopatadine 0.1% (Patanol)
Ocular 2nd gen AH Selective H1 antag Better than Ketotifen AH
27
What composes Coricidin HBP cough and cold?
Dextromethorphan | Chlorpheniramine
28
Cetirizine
(PO) 2nd Gen AH - AR - Nonsedating - Cat B
29
What steroid is considered soft or smart?
Ocular Loteprednol (low rate SEs)
30
Cyproheptadine
(PO) 1st Gen AH - For Serotonin Syndrome
31
Anticholinergics is best for?
Rhinorrhea
32
Cat B allergy drugs
``` Chlorpheniramine (Preferred AH) Diphenhydramine Loratadine Cetirizine Budesibude (Perferred INS) Montelukast (LTRA) Ipratropium Cromolyn Sodium (Mast cell stabilizer) ```
33
Pseudoephedrine (PSE)
(PO) Direct acting A>B agonist (displaces NEPI) Nasal Decon - DOC preggo 2nd tri or later
34
Brompheniramine
(PO) 1st Gen AH
35
Another name for Rebound congestion?
Rhinitis Medicamentosa
36
What are the 2 (PO) decongestants
PE and PSE
37
MOA - Muscarinic antag
Ipratropium
38
Tetrahydrozoline 0.05%
Ocular Decongestants (Visine original)
39
MOA - Direct A1/A2 ag
Oxymetazoline
40
Conjunctivits commonly occurs with
Seasonal AR
41
Cetirizine w/ PSE
AH - Decon combo - 2nd gen
42
Cold compresses can effectively reduce what?
Ocular itching
43
What are the different Visine?
Visine A - contains Naphazoline Visine LR - Oxymetazoline 0.025% Visine Original - Tetrahydrozoline 0.05%
44
What is Oral burst therapy?
(PO) prednisone daily 5-7D for severe AR
45
Azelastine HCL/Fluticasone Propionate
(IN) Steroid Combo - Seasonal AR for >6yo
46
Beclomethasone
(IN) Steroids -Sig decrease growth velocity
47
Chlorpheniramine
(PO) 1st Gen AH | Perferred AH for preggo
48
Ketotifen 0.025%
Ocular AH 2nd gen Selective H1 antag - OTC
49
What cells are concentrated in nose and conjunctiva?
Mast cells
50
Fluticasone furoate
(IN) Steroids - low bioavail
51
When does max effects of INS occur?
1-2wks
52
Ketorolac
Ocular NSAID - for eye pain/discomfort
53
Budesonide
(IN) Steroids - Preferred for pregnancy (B)
54
Mometasone
(IN) Steroids - low sys bioavailability
55
Phenylephrine
Synthetic A1 Agonist - increase BP -monitor | Eye redness, Nasal decon, Hemrrhoids
56
MOA - decrease prostaglandin production
NSAID
57
Conjunctivitis triad
Itching Injection Chemosis (edema)
58
Levocetirizine
(PO) 2nd Gen AH - AR
59
Triamcinolone
(IN) Steroids
60
Fexofenadine
(PO) 2nd Gen AH - AR - Nonsedating
61
MOA - Inhibits both early/late phase mediators
INS
62
Cromolyn 4%
Ocular Mast Cell Stablizers Prophylaxis, combined w/ ocular AH
63
Flunisolide
(IN) Steroids - Sig decrease growth velocity
64
Which AH is more perferred, 1st Gen or 2nd Gen?
2nd Gen (less sedation/SEs)
65
MOA - Competitive H1 antag or inverse ag
AH
66
Fluticasone propioniate
(IN) Steroids - low sys bioavailability
67
Intranasal Saline
Alternative - recommend to ALL pts
68
What drug interations are asccociated with Decongestants?
MAOI w/in 2wks
69
Azelastine (Nasal)
(IN) AH - AR - Crosses BBB
70
Naphazoline 0.1%
Ocular Decon - most potent
71
Olopatadine
``` 2nd Gen (IN) AH-H1 Select - AR Better than Azelastine AH ```
72
What are the 2 (IN) decongestants
PE and oxymetazoline
73
Which has more efficacy, (IN) AH or (PO) AH?
(IN) AH
74
Brompheniramine + PE
AH - Decon combo - 1st gen
75
Desloratadine
(PO) 2nd Gen AH - AR
76
Chlorpheniramine w/PE
AH- Decon combo - 1st gen
77
INS best for?
Everything to include eye S/S
78
Promethazine
(PO) 1st Gen AH - For N/V Makes you sleepy
79
Naphazoline 0.025% and Pheniramine 0.3%
Ocular AH and Decon Combo (Visine A)
80
Loteprednol 0.2%
Ocular Steroids - Approved for seasonal allergic conjunctivitis

Junior Pharm II (8 decks)

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