Other conditions Flashcards

1
Q

What is Sjogren’s syndrome?

A

Chronic AI inflammatory disease commonly in middle-aged women.
Commonly comes with sicca syndrome (dry mouth) or other systemic symptoms like arthritis, Raynaud phrenomenon etc

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is epididymitis?

A

Inflammation of epididymis, a/w genitourinary tract infections.
Present with gradual pain onset and swelling of affected scrotum

Positive Prehn sign

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is testicular torsion?

A

Testis rotated on its vascular pedicle causing ischemia.

Urologic emergency - irreversible damage after 12 hrs of ischemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is Spherocytosis?

A

Inherited disorder that changes shape of RBCs and lowers RBC life

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is opthalmoplegia?

A

Also called extraocular muscle palsy, paralysis of the extraocular muscles that control the movements of the eye.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is Lamber-Eaton myasthenic syndrome?

A

Autoimmune condition that affects NMJ , inhibiting ACh release.
Presents with muscle weakness (that improves with repetitive stimulation) and autonomic dysfunction e.g. dry eyes, erectile dysfunction

Often paraneoplastic syndrome, commonly from small cell lung cancer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is Guillain-Barre syndrome?

A

Symmetrical ascending LMN weakness, arreflexia, sensory impairment. Progressive over a period of 1-2 weeks.
May have preceding infection

Monitor for signs of respiratory insufficiency!

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is myelodysplastic syndrome?

A

Group of cancers in which immature blood cells in the bone marrow do not mature or become healthy blood cells.

Can cause macrocytic anemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is Red Cell aplasia?

A

Rare disorder that causes anemia secondary to failure of erythropoiesis.
Causes normocytic, normochromic anemia.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is pancytopenia?

A

Decrease in number of all 3 cell lines:
Erythrocytes, leukocytes, platelets

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is microangiopathic haemolytic anaemia (MAHA)?

A

Hallmark of thrombotic microangiopathy.
Anaemia due to physical damage to RBCs after occlusion of arterioles and capillaries due to fibrin deposition or platelet aggregation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is Disseminated Intravascular Coagulation (DIVC)?

A

Systemic activation of clotting cascade, platelet consumption and subsequent exhaustion of clotting factors.
Often leads to widespread thrombosis and haemorrhage

a/w trauma, shock, sepsis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What is Haemarthrosis?

A

Condition of articular bleeding into joint cavity. Can present with pain, swelling and decreased ROM of joint.

Often due to haemophilia or other bleeding disorders

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is Hereditary Hemorrhagic Telangiectasia? (Osler-Weber-Rendu syndrome)

A

AD disorder causing abnormal vascular development. May not have capillaries.
Commonly presents with nosebleeds but can also cause acute/chronic GIT bleeding.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is chilaiditi syndrome?

A

In CXR, a segment of the intestine is interposed between the liver and diaphragm

Go google the image

Benign condition, can be mistaken for pneumomediastinum leading to needless workup

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is Psoriasis?

A

Chronic inflammatory skin disorder.
Manifests as sharply demarcated, erythematous, scaly, pruritic plaques.
Other findings include arthritis and nail involvement.

Clinical diagnosis

17
Q

What is Kartagener syndrome?

A

Autosomal recessive ciliary disorder comprising the triad of situs inversus, chronic sinusitis, and bronchiectasis.

Rare condition

18
Q

What is Wilson’s Disease?

A

Abnormal copper accumulation in body. Involves brain, liver, cornea.

Rare, autosomal recessive disorder

19
Q

What is Carcinoid Syndrome?

A

Neuroendocrine tumours, releases serotonin.
Causes tricuspid regurg, chronic diarrhoea, facial flushing

20
Q

What is Stauffer syndrome?

A

Rare paraneoplastic syndrome of RCC.
Causes raised ALP, ESR, hepatosplenomegaly, thrombocytosis, long PT time

21
Q

what is Trosseau sign of malignancy?

A

presence of spontaneous, migratory, painful edema and thrombosis involving the superficial and deep veins in patients with cancer