Other Bacteria Flashcards
Undulating fever due to contaminated dairy
Brucellosis
Tx doxycycline + rifampicin
Tularemia
Francisella Tularensis
Tx Streptomycin or gentamicin
Gram (-) rods w/ bipolar (safety pin) staining causing bubonic, pneumonic and septicemic plague
Yersinia pestis
Tx. Streptomycin and tetracycline
Most virulent bacteria
Yersinia pestis
Gram (-) encapsultated rod forming buttery colonies with musty odor
Animal bites and osteomyelitis
Pasteurella multocida
Tx. Pen G
Aerobic, acid fast rods grown in Ziehl-Neelsen
Mycobacterium tuberculosis
Assay used for mycobacterium drug resistance
Luciferase assay
Most important virulence factor in Mycobacterium
Cord factor
Virulence factor in Mycobacterium that prevents phagosome-lysosomal fusion
Exported repetitive protein (sulfatides->surface glycolipids
Virulence factor in Mycobacterium that elicits delayed hypersensitivity
Tuberculin surface proteins
Primary complex in PTB
Ghon’s complex
Radiologically detectable colonization (Ranke’s complex)
Reactivation Tuberculosis
Simon’s Focus
CXR: Cicatricial changes, subpleural blebs, cavitations
Secondary colinzation w/ A. fumigatus
Positive Mantoux test for Low risk population
> 15 mm
Positive Mantoux test for HIV+, AIDS, old TB Immunocompromise population
> 5 mm
Positive Mantoux test for High risk population
> 10 mm
Most common extrapulmonary for of TB
Scrofula (TB Lymphadenitis)
Other uses of BCG vaccine aside from TB prevention
Adjunct treatment for bladder CA
Causes pulmonary disease in immunocompromised host (AIDS patient with CD4<50)
Mycobacterium Avium-intracellulare complex (MAI, MAC)
Prophylaxis: Azithromycin
Aerobic, acid fast rods w/c can’t be cultured in vitro and causes neural disease w/ dermatologic manifestation
Mycobacterium leprae
Leprosy with hypopigmented plaques, thickened superficial nerves, and significant anesthesia
Tuberculoid Leprosy
Tx. Dapsone and rifampin
Leprosy with leonine facies, erythema nodosum leprosum
Lepromatous leprosy
Tx. dapsone, rifampin and clofazimine
DOC for erythema nodosum leprosum
Thalidomide