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Other Bacteria Flashcards

1
Q

Undulating fever due to contaminated dairy

A

Brucellosis

Tx doxycycline + rifampicin

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2
Q

Tularemia

A

Francisella Tularensis

Tx Streptomycin or gentamicin

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3
Q

Gram (-) rods w/ bipolar (safety pin) staining causing bubonic, pneumonic and septicemic plague

A

Yersinia pestis

Tx. Streptomycin and tetracycline

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4
Q

Most virulent bacteria

A

Yersinia pestis

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5
Q

Gram (-) encapsultated rod forming buttery colonies with musty odor
Animal bites and osteomyelitis

A

Pasteurella multocida

Tx. Pen G

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6
Q

Aerobic, acid fast rods grown in Ziehl-Neelsen

A

Mycobacterium tuberculosis

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7
Q

Assay used for mycobacterium drug resistance

A

Luciferase assay

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8
Q

Most important virulence factor in Mycobacterium

A

Cord factor

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9
Q

Virulence factor in Mycobacterium that prevents phagosome-lysosomal fusion

A

Exported repetitive protein (sulfatides->surface glycolipids

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10
Q

Virulence factor in Mycobacterium that elicits delayed hypersensitivity

A

Tuberculin surface proteins

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11
Q

Primary complex in PTB

A

Ghon’s complex

Radiologically detectable colonization (Ranke’s complex)

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12
Q

Reactivation Tuberculosis

A

Simon’s Focus
CXR: Cicatricial changes, subpleural blebs, cavitations
Secondary colinzation w/ A. fumigatus

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13
Q

Positive Mantoux test for Low risk population

A

> 15 mm

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14
Q

Positive Mantoux test for HIV+, AIDS, old TB Immunocompromise population

A

> 5 mm

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15
Q

Positive Mantoux test for High risk population

A

> 10 mm

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16
Q

Most common extrapulmonary for of TB

A

Scrofula (TB Lymphadenitis)

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17
Q

Other uses of BCG vaccine aside from TB prevention

A

Adjunct treatment for bladder CA

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18
Q

Causes pulmonary disease in immunocompromised host (AIDS patient with CD4<50)

A

Mycobacterium Avium-intracellulare complex (MAI, MAC)

Prophylaxis: Azithromycin

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19
Q

Aerobic, acid fast rods w/c can’t be cultured in vitro and causes neural disease w/ dermatologic manifestation

A

Mycobacterium leprae

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20
Q

Leprosy with hypopigmented plaques, thickened superficial nerves, and significant anesthesia

A

Tuberculoid Leprosy

Tx. Dapsone and rifampin

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21
Q

Leprosy with leonine facies, erythema nodosum leprosum

A

Lepromatous leprosy

Tx. dapsone, rifampin and clofazimine

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22
Q

DOC for erythema nodosum leprosum

A

Thalidomide

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23
Q

Condition associated with a hard nontender swelling with sinus tracts draining sulfur granules in a setting of broken jaw or dental extraction

A

Actinomycosis (lumpy jaw)

Tx. Pen G + drainage

24
Q

African with unilateral swelling of the jaw. Think of ?

A

Burkitt’s, Lymphoma, EBV

25
Q

Gram (+) aerobic acid fast (Fite-Faraco- stain) which causes mycetomas and lung and brain abscesses (orange colonies)

A

Nocardia asteroides, Nocardiosis

Tx. TMP-SMX

26
Q

Smallest free living organism

A

Mycoplasma Pneumoniae

27
Q

Manifest as broad based ataxia, (+) romberg, charcot joints, stroke w/o hypertension

A

Tertiary Syphilis

28
Q

Tertiary syphilis

A 
Gummas
Neurosyphilis
     - tabes dorsalis
     - dementia paralytica
Aortitis --> endarteritis
29
Q

Manifest with snuffles/saddle nose; mulberry molars; hutchinson triad, saber shins, higoumenakis sign, clutton’s joints, pulmonary hemorrhage

A

Congenital syphilis

30
Q

Hutchinson triad

A

Hutchinson teeth, deafness, keratitis

31
Q

Detection for Primary syphilis

A

Dark field microscopy

32
Q

Detection for Secondary & Tertiary syphilis

33
Q

Largest medically important bacteria

A

Borrelia burgdorferi

34
Q

Lyme disease is transmitted through

A

deer ticks (Ixodes scapularis)

35
Q

Pathognomonic sign: Erythema chronicum migrans

A

Lyme Disease

36
Q

Stage of lyme disease with autoimmune migratory polyarthritis (onion skin lesions),acrodermatitis chronica atrophicans

37
Q

Stage of lyme disease with myocarditis (AV block), meningitis and bells palsy

38
Q

Lyme Disease

A 
BAKE a Key Lyme pie
Bell's palsy
Arthritis
Kardiac block
Erythema chronicum migrans
39
Q

DOC for lyme disease

A

Early: Doxycycline
Late: IV penicillin or ceftriaxone

40
Q

Relapsing fever

A

Borrelia recurrentis

Tx Tetracycline

41
Q

Shepherd’s crook

A

Leptospira interrogans

42
Q

Obligate intracellular bacteria
Cell wall lacks muramic acid
Grown in cycloheximide culture

A

Chlamydia Trachomatis

43
Q

Obligate intracellular bacteria

A

Chlamydia Trachomatis

Ricketssia

44
Q

Chronic keratoconjunctivitis progressing to scarring and blindness

A

Trachoma

Chlamydia trachomatis

45
Q

Etiologic type of trachomatis that cause trachoma

A

C. trachomatis types A-C

46
Q

Etiologic type of trachomatis that cause genital tract infection

A

C. trachomatis types D-K

47
Q

Etiologic type of trachomatis that cause neonatal pneumonia

A

C. trachomatis types D-K

48
Q

Etiologic type of trachomatis that cause lymphogranuloma venereum

A

C. trachomatis types L1-L3

49
Q

Papule or vesicular w/c ulcerates and leads to suppurative inguinal lymphadenitis (buboes)
(+) Frei test

A

Lymphogranuloma venereum

50
Q 
DOC of Chlamydia infections
STD
Conjunctivitis
LGV
Psittacosis
A

STD Azithromycin
Conjunctivitis Erythromycin
LGV Doxycycline
Psittacosis Azithromycin

51
Q

Condition where there is sudden onset pneumonia w/ malaise, fever, anorexia, sore throat, photophobia, severe headache
(+) bird exposure (bird fancier’s disease)

A

Psittacossis

52
Q

(+) Weil-Felix reaction

A

Rickettsiae

53
Q

Cat scratch fever in immunocompetent individuals

Bacillary angiomatosis in immunocompromise individuals

A

Bartonella henselae

54
Q

Reservoir dogs

forms morulae in cytoplasms of monocytes

A

Ehrlichia chaffeensis

55
Q

Messenteric Adenitis (pseudoappendicitis)

A

Yersinia enterocolitica

56
Q

Granuloma Inguinale (Donovanosis)

A

Klebsiella granulomatis

57
Q

small painless papule ulcerates to form beefy red ulcers with velvety surface
pseudobuboe formation

A

Granuloma Inguinale (Donovanosis)

Microbiology (10 decks)

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