DNA viruses Flashcards

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1
Q

All enveloped viruses acquire their envelope from plasma membrane except for

A

Herpes virus (from nuclear membrane)

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2
Q

Purified nucleic acids of most dsDNA except for ______ are infectious

A

Poxviruses and HBV

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3
Q

Only live attenuated vaccine that may be given to HIV positive patients

A

MMR

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4
Q

DNA viruses

A
DNA viruses are HHAPPPPy viruses
Hepadna
Herpes
Adeno
Pox
Parvo
Polyoma
Papilloma
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5
Q

All DNA viruses have double-stranded DNA except

A

Parvovirus

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6
Q

All DNA viruses have linear DNA except

A

Papilloma, polyoma, hepadna

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7
Q

All DNA viruses are icosahedral except

A

Poxvirus

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8
Q

All DNA viruses replicate in the nucleus except

A

Poxvirus (cytoplasm)

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9
Q

Condition with bright red cheek rash (slapped cheeks) with fever coryza and sore throat

A

Erythema Infectiosum (Fifth Disease)

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10
Q

Etiology of Erythema Infectiosum (Fifth Disease)

A

Parvovirus B19

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11
Q

Causes transient but severe aplastic anemia in children sickel cell anemia, thalassemia or spherocytosis

A

Parvovirus B19

Aplastic crisis

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12
Q

Fetal infection caused by Parvovirus B19

A

Hydrops fetalis (2nd trimester)

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13
Q

Only virus with fiber (Penton fiber)

A

Adenovirus

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14
Q

Causes hemorrhagic cystitis

A

Adenovirus

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15
Q

Papilloma virus infects squamous cells and induce formation of cytoplasmic vacuole

A

Koilocytes

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16
Q

What genes in Papilloma virus encode proteins that inactivate tumor suppressor genes

A

genes E6 and E7

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17
Q

HPV that causes skin and plantar warts

A

HPV 1-4

18
Q

HPV that causes genital warts (condylomata acuminata) and respiratory tract papillomas

A

HPV 6 and 11

19
Q

HPV that causes carcinoma of cervix, penis and anus

A

HPV 16,18, 31,33

20
Q

DOC for HPV

A

Genital warts : Podophyllin
Skin warts: Liquid nitrogen
Plantar warts: Salicylic acid

21
Q

Causes progressive multifocal leukoencephalopathy (PML) in patients with AIDS

A

JC Polyoma virus

22
Q

Causes hemorrhagic cystitis and nephropathy in patients with solid organ and bone marrow transplant

A

BK Polyoma virus

23
Q

Site of latency period of herpes virus

A

HSV-1 - trigeminal ganglia

HSV-2 Lumbosacral ganglia

24
Q

DOC for herpes

A

Acyclovir

25
Q

Site of latency period for Varicella zoster virus

A

Dorsal root ganglia

26
Q

Condition where in all stages of the disease are present at a single time

A

Varicella

27
Q

A syndrome that is a complication of varicella

A

Reye’s syndrom

28
Q

A condition where in there is involvement of geniculate ganglion causes facial nerve paralysis

A

Ramsay hunt syndrome / Herpes zoster oticus

29
Q

Blueberry muffin syndrome

A

CMV
Congenital rubella
Disseminated Neuroblastoma

30
Q

Causes Heterophil-negative mononucleosis

A

CMV

31
Q

DOC for CMV

A

Ganciclovir

32
Q

3 causes of mononucleosis

A

CMV & Toxoplasmosis ( heterophil negative)

EBV (heterophil positive)

33
Q

Virus associated with burkitt’s lymphoma

A

EBV

34
Q

Virus associated with nasopharyngeal CA in chinese people and hairy leukoplakia in AIDS patient

A

EBV

35
Q

Virus associated with Kaposi’s sarcoma

A

Human Herpesvirus -8

36
Q

Largest virus

A

Smallpox

37
Q

Disease with pinkish papular skin lesions with an umbilicated center

A

Molluscum contagiosum

Tx. Cifodovir

38
Q

Only DNA virus that produces DNA by reverse transcription with mRNA as the template

A

Hepatitis B virus

39
Q

DOC of Hepatitis virus

A

Interferon alpha

Lamivudin

40
Q

Associated with Polyarteritis nodosa

A

Hepatitis B