Othalamic Flashcards
diagnostic rx
anesthetic agents: opthane
staining agents: florescein dye
mydriatics (dilate) and cycloplegics (paralysis): homatrpine
miotics (constrict): pilocarpine
rx keratoconjunctivitis
artificial tears
topical cyclosporine
tx for allergic conjunctivitis - severe case
cool compress antihistimine/decongestant lubricant steroid NSAID mast cell stabilizer
bacterial conjunctivitis drug of choice
.03% tobramycin
polymyxin
*more severe infection: .3% ofloxacin
topical antibiotic therapy
aminoglycosides
fluoroquinonolones: broad spectrum
IV ab for gonococcal or chlamydial
erythromycin for s pnemo and h flu
Herpes simplex keratitis
trifluridine
CMV keratoconjunctivitis
ganciclovir
cidofovir
foscarnet
glaucoma rx first line
beta blockers, alpha adrenergic agonist, topical carbonic anyhydrase inhibitors: decrease aqueous production
prostaglandin analogs, parasympathomimetics, sympathomimetics: increase aqueous outflow
topical antimicrobials
bacitracin
neomycin
polymyxin
neosporin
indications for topical antimicrobials
superficial bacterial skin infections, eyes, and external ear infections
MOA: polymyxin disrupts structure of bacterial cell membrane
bacitracin interferes with peptidoglycans of cell wall
impetigo tx
mupirocin/bactroban
neosporin: less effective
* only use topical if limited lesions
muprocin/bactroban
topical antibiotic
inhibits bacterial protein synthesis
used in MRSA
tinea corporis tx
ketoconazole: inhibits sterol synthesis of fungal cell membranes
high potency corticosteriods
class I tx should not exceed 2-4 weeks
first line therapy for atopic derm/exczema
1st line: topical corticosteriods
last line: topical calcineurin inhibitors
pruritis/hives
systemic antihistimines: loratadine (claritin) or cetirizine (zyrtec)
are topical antihistimines effective?
no
rx for acne
salicylic acid benzoyl peroxide topical retinoids antibacterial agents antisebum agents (oral contraceptives, spironalactone, isotretinoin)
first line tx for all acne
tretinoin topical retinoid: comedolysis, induction of orthokeratosis and inhibition of inflammation.
first line topical therapy for acne
benzoyl peroxide: potent bactericidal, keratolysis, comedolysis
isotretinoin
accutane: reduction of hyperkeratinization, reduction in number of sebaceous glands and sebum production reduction
* teratogenic
tx for psoriasis
topical corticosteroids
topical vit D analog
phototherapy
systemic oral steroids, chemotherapy agent, TNF alpha inhibitors