Osteoporosis Flashcards
1
Q
what is osteoporosis?
A
a metabolic bone disease characterised by low bone mass and micro architectural detonation
2
Q
causes of osteoporosis? (4)
A
GI
Endocrine
Rheumatic
Medications
3
Q
osteoporosis management?
A
minimising RF
good calcium and vitamin D status
falls prevention
medication
4
Q
when do you refer for DXA scanning?
A
when FRAX score is more than 10%
5
Q
what are the 4 medications used in osteoporosis?
A
Bisphosphonates (main option)
HRT
Selective oestrogen receptor modulator
Denosumab
6
Q
Selective oestrogen receptor modulator gives lack of protection where?
A
hip site
7
Q
what is the first line treatment?
A
bisphosphonates
8
Q
bisphosphonate side-effects? (2)
A
oesophagitis
iritis
9
Q
what is Denosumab a monoclonal AB against?
A
RANKL
10
Q
what does denosumab do?
A
reduced osteoclastic bone resorption
