Osteoporosis Flashcards
What is the most prevalent bone disease in the world?
Osteoporosis
How many osteoporotic fractures occur each year?
more than 1.5 million.
What is occurring due to osteoporosis?
- Normal homeostatic bone turnover is altered.
- The rate of bone resorption is greater than the rate of bone formation resulting in loss of total bone mass.
What happens to a patients bones due to osteoporosis?
Bone becomes porous, brittle, and fragile and breaks easily under stress.
What types of fractures typically result from osteoporosis?
- Compression fractures of the spine
- Fractures of the neck
- Fractures in the Intertrochanteric region of the femur
- Colles’ fractures of the wrist
How many people does osteoporosis affect each year?
10 million
What percentage of patients affected by osteoporosis are women?
80%
Why is osteoporosis often called the silent disease?
Bone loss occurs without symptoms. The first sign may be a fracture due to weakened bones. A sudden strain or bump can break the bone.
What is remodeling?
A process where bone is constantly being broken down and rebuilt
True or false:
Bone is not a living tissue. Once it is fully built that is it.
False:
Bone is a living tissue- constantly being renewed.
The loss of living bone tissue does what?
It makes the bones fragile and more likely to fracture
If a women has osteoporosis her risk for hip fracture equals her combined risk for what?
Risk of breast, uterine, and ovarian cancer combined.
After a hip fracture- what percentage of patients need long-term care facilities after?
15-20%
What is the percentage of increased risk of death during the first year following a hip fracture?
20%
What genetic risk factors are there for osteoporosis?
- Caucasian or Asian
- Female
- Family history
- Small frame
Why do genetic risk factors of osteoporosis lead to osteoporosis?
Low bone mass
What age risk factors are there for osteoporosis?
- Postmenopause
- Advanced age
- Low testosterone in men
- Decreased calcitonin
Why do the age risk factors lead to osteoporosis?
Hormone inhibit bone loss
What are the nutrition risk factors for osteoporosis?
- Low calcium intake
- Low Vitamin D intake
- High phosphate intake (carbonated beverages)
- Inadequate calories
Why do the nutrition risk factors for osteoporosis lead to osteoporosis?
-Reduces nutrients needed for bone remodeling
What are the physical exercise risk factors for osteoporosis?
- Sedentary
- Lack of weight bearing exercise
- Low weight and body mass index
Why can the physical exercise risk factors lead osteoporosis?
Bones need stress for bone maintenance
What are the lifestyle choices risk factors for osteoporosis?
- Caffeine
- Alcohol
- Smoking
- Lack of exposure to sunlight
Why can the lifestyle risk factors lead to osteoporosis?
It reduces osteogenesis in bone remodeling
What are the medication risk factors for osteoporosis?
- Corticosteroids
- Antiseizure meds
- Heparin
- Thyroid hormone
What are the comorbidity risk factors for osteoporosis?
- Anorexia nervosa
- Hyperthyroidism
- Malabsorption syndrome
- Kidney failure
Why can the medications and comorbidity risk factors lead to osteoporosis?
They affect calcium absorption and metabolism
After menopause what happens to the bones?
Bone removal accelerates due to decrease in estrogen.