Diabetes Flashcards
What is diabetes usually caused from?
Obesity- bad diet and no exercise
What is diabetes characterized by?
Hyperglycemia
What defects is diabetes caused by?
Defects in:
Insulin secretion, insulin action or both
What portion of diabetes cases are undiagnosed?
one third
In terms of diabetes:
Minority populations and older adults are…
Disproportionately affected
In patients with diabetes:
What needs to happen to the patients insulin and glucagon levels?
Insulin levels need to be increased and glucagon levels need to be decreased.
What does insulin (beta) mainly do?
Moves glucose from blood into cells
What does insulin inhibit?
It inhibits the breakdown of stored glucose, protein and fat
What does insulin accelerate?
It accelerates transport of amino acids into cells
What does insulin enhance?
It enhances storage of dietary fat in adipose tissue
What does insulin stimulate?
It stimulates storage of glucose in the liver and muscle as glycogen
What does insulin transport and metabolize?
It transports and metabolizes glucose for energy
When is glucagon (alpha) released?
When serum glucose decreases
Glucagon stimulates what?
It stimulates glycogenolysis in the liver
Glucagon increases what?
Increases formation by liver of glucose from noncarbohydrate sources
Gluconeogenesis is described as?
The formation of glucose from noncarbohydrate sources
Type 2 diabetes affects what percentage of patients diagnosed with diabetes?
90 to 95%
Type 1 diabetes affects what percentage of patients diagnosed with diabetes?
5-10%
Gestational Diabetes affects what percentage of pregnancies?
2-5%
What happens to a patient’s risk of diabetes if they come down with gestational diabetes?
it increases
What are the two things that occurs in a patient if they are diagnosed with type 2 diabetes?
A decreased sensitivity to insulin and impaired secretion of insulin
What secondary diagnosis does a patient frequently have if they have type 2 diabetes?
Hypertension
What is type 2 diabetes initially treated with?
Diet and exercise
What type of medication is a patient with type two diabetes initially put on?
A pill form of hypoglycemic agents.
If the pill form of hypoglycemic agents doesn’t work then a patient with type two diabetes will likely be put on?
Insulin
What age group is type two diabetes increasing in?
Children
Impaired insulin secretion from the pancreas and increased basal hepatic glucose production leads to what?
Hyperglycemia
Gastrointestinal absorption of glucose and decreased insulin-stimulated glucose uptake in the muscle leads to what?
Hyperglycemia
Patients who are thirty years of age or older are at a higher risk for what?
Type 2 diabetes
What BMI are patients of the Asian American decent at a higher risk for type 2 diabetes?
greater than 23
What races have an increased risk of type two diabetes?
African Americans, Hispanics, Native Americans, and Alaskan Natives
Metabolic syndrome is a risk factor for what?
Type 2 diabetes
Hypertension, elevated triglyceride, and decreased HDL are risk factors for what?
Type 2 diabetes
What disease is a patient at risk for if they have polycystic ovary syndrome?
Type 2 diabetes
What are the two things a patient typically goes to the doctor for and end up being diagnosed with type 2 diabetes?
An eye issue or a wound that won’t heal
What does polydipsia mean?
Increased thirst
What does polyphagia mean?
Increased hunger
Does type 2 diabetes have a slow or fast onset of clinical manifestations?
Slow
Skin infections, blurred vision, fatigue, paresthesias, polydipsia and polyuria are all clinical manifestations of what?
Type 2 diabetes
History of Hypertension and obesity could potentially lead to what?
Type 2 diabetes
What do you need to include when taking vital signs in a patient suspected of having type two diabetes?
Orthostatic blood pressure
In a patient who has type two diabetes what happens when taking orthostatic blood pressure?
It takes 10-15 minutes for brain to regulate so their BP will be different each time.
During a physical exam:
What would be happening to the skin that would suggest the patient has type 2 diabetes?
The back of their neck turns dark and looks dirty. Due to a fungal infection.
When doing an eye exam on a patient suspected to have type 2 diabetes what must you make sure you use?
A fundoscope
When doing a physical exam on a patient who is suspected to have type 2 diabetes: what should you make sure you do when checking out their feet?
Check their pedal pulses and reflexes.
Check for sensation in their feet to rule out neuropathy.
Check for any wounds that aren’t healing.
When checking the patients hemoglobin A1C- what levels would diagnose them with diabetes?
Greater than or equal to 6.5%
What is a bench mark diagnostic test for a patient with diabetes?
Hemoglobin A1C
During an oral glucose tolerance test: what would diagnose a patient with diabetes?
If their two hour plasma glucose was anything over 200