Osteoporosis

Question 1

Cortical bone

Answer 1

Dense, compact, 80% of bone

Question 2

Trabecular bone

Answer 2

Spongy scaffolding on inside of bone to support cortical

Question 3

Bone development

Answer 3

Bone growth: increase in size (completed by 14 - 17)
Bone remodeling: shaping, completed by early adulthood
Bone remodeling: reshaping

Question 4

Resorption

Answer 4

During bone remodeling

Surface of bones broken down by osteo C lasts

Question 5

Formation of new bones

Answer 5

During bone remodeling

Done by osteo B lasts (cells that produce collagen)

Question 6

Epiphyseal plate

Answer 6

Growth plate: growth of new cell layers, closes after growth and never reopens

Question 7

Osteoporosis RISKS

Answer 7

• age
• gender (women)
• genetics
• nutrition
• physical activity (weight bearing exercises sstrengthen bones and weight lifting increases muscle which increases bones)

Question 8

Osteoporosis PREVENTION

Answer 8

Anti-resorptive medications (inhibit osteoclasts)

Adequate Vitamin D/calcium

Question 9

Bone flow chart

Answer 9

Bone mass increases during growth years to peak bone mass at age 30, then decreases until menopause

Menopause: leads to increased bone loss due to lack of estrogen

BC –> decreased risk of osteoporosis, but increased risk of breast cancer
No BC –> decreased risk of breast cancer, but increased risk of osteoporosis

Question 10

Bone fractures

Answer 10

Forearm/wrist: 50yo +, early warning signs

Spinal vertebrae: 55 - 70yo

Hip: 70yo, most serious, takes longer to heal –> bedsores –> infection –> death