Osteophathies fragilisantes Flashcards

1
Q

Osteopathies fragilisantes

A

OP, osteomalacie, ostéogenese imparfaite, tumeurs, Paget..

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2
Q

Etiologies osteomalacie

A

carence vit D, hypophosphoremie

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3
Q

Diagnostic osteomalacie

A

histomorphometrie, biomarqueurs

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4
Q

Tt osteomalacie

A

tt etiologique, Ca et vit D

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5
Q

Tt osteogenese imparfaite

A

BP chez enfant, adulte (?)

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6
Q

Diagnostic osteogenese imparfaite

A

clinique, DMX

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7
Q

définition maladie de Paget

A

oseodystrophie benigne acquise avec hypertrophie os, trabeculation grossiere et anarchique, dédifferentiation corticomédullaire, hypervascularisation os

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8
Q

Epidemiologie maladie Paget

A

homme, >50ans, 10% des >80ans

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9
Q

Clinique maladie Paget

A

dlrs os (bassin>rachis>crane>os longs) chaleur locale, déformation osseuse

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10
Q

Déformations osseuses dans maladie de Paget

A

hypertrophie cranienne ou articulation periph, incurvation d’un os long

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11
Q

Paraclinique maladie Paget

A

BIO : augmentation de : PAL, Cauri, hydroxiprolinurie, desoxyproliurie, CTX, NTX
BPCa N, CRP et VS N, EPP N
Radio

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12
Q

Aspects radio maladie Paget

A

hypertrophie osseuse, condensation trabéculaire avec travées, épaississement corticale, dédifférentiation corticomédullaire
crane : aspect floconneux, épaississement cortical

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13
Q

Complications maladie Paget

A

, degenerescence sarcomateuse (1%), arthrose IIaire, hyperCa d’immob, atteinte nerveuse, IC, AVC

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14
Q

Surveillance maladie de Paget

A

PAL tous les 3-6mois, Radio/an, scintig os/5ans

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15
Q

PEC maladie Paget

A

sympto : AINS
spé : BP (si sympto, loca os crane, vertebre, bassin, os longs, complic, preop, hyperCa)
efficace si normalisation PAL

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