Osteomyelitis and Implant-associated infections Flashcards
What is the name of the artery that supply the subchondral bone? A Nutrient arteries of the epiphysis B Epiphyseal branching artery C Metaphyseal artery D Cortical capillaries
A
Where does most hematogenous osteomyelitis occur? A Diaphysis B Epiphysis C Metaphysis D Periosteum
C
What is NOT an extraosseous blood supply to the bone in an immature dog? A Nutrient artery B Metaphyseal artery C Nutrient artery of the epiphysis D Venous sinus
D (this is within the bone and gets blood supply from the other above arteries)
Put the steps of biofilm formation in order:
Dissemination/detachment,
Reversible attachment,
growth and differentiation, irreversible attachment,
reversible attachment–> irreversible attachment–> growth and differentiation –> followed by dissemination (or detachment)
Which of the following is true?
A Conditioning film is a biomaterial composed of adsorbed macromolecules from the local tissues
B The glycocalyx is a formation of endopolysaccharides that allow for the irreversible binding
C Biofilm bacteria are highly resistant to antimicrobial agents because they lack perfusion and rapidly grow
A is true
B ?matrix of exopolysaccharide
C (false, lack perfusion, quiescent growth pattern, and harsh microenvironment)
What is quorum sensing?
ability of bacteria to coordinate gene expression based on population density and role of secreted signal molecules (autoinducers)
Which is NOT a theory for hematogenous metaphyseal osteomyelitis?
A. Sluggish blood flow
B. Overreaction fo systemic leukocytes
C. Hematoma results in vascular obstruction
D. Transphyseal vessels lacking at birth
B. Apparent lack of systemic leukocytes, relying on tissue-based macrophages
What is NOT a bioabsorbable material that can be used to deliver local antibiotics? A. PMMA B. Collagen fleece C. bone graft substitues D. polymer hydrogel
A PMMA
