osteochondrosis

Question 1

Which of the following is true for nutrition and osteochondrosis?
• Diets low in calcium and vitamin D3 will affect endochondral ossification
• Great Dane Puppies fed ad libitum developed relative failure of cartilage maturation
• The nutrition in large breed dogs is the reason why they are predisposed to OCD
• Diet has not been shown to have any effect on endochondral ossification

Answer 1

B true: ad libitum not great

A diets HIGH in Ca or Vit D affect endochondral ossification
C. Multifactorial

Question 2

Which of the following is false regarding the pathogenesis of OCD?
• Type I lesions are central, and type II lesions are vascularized
• Juvenile vascular supply is consistent within a species
• The focal disease theory proposes that vascular trauma results in necrosis of subchondral bone or epiphyselal cartilage canals, with secondary effects on the overlying cartilage
• The generalized disease theory is more widely accepted and OCD results from dyschodroplasia and biomechanical stress

Answer 2

D is false
Thought to be focal necrosis of cartilage canals –> cartilage ischemia–> infarcted cartilage prevents endochondral ossification and cartilage proliferation continues

Question 3

Name zones articular cartilage from joint to bone

HINT: Some Toddlers Read (too many) Comics

Answer 3

Superficial zone
Transitional zone
Resting zone
(tidemark)
Calcified cartilage zone)
Subchondral bone