Osteomalacia

Question 1

How is osteomalacia

Answer 1

Replacement of resorbed bone with unmineralised osteoid (bone softening secondary to low vit D levels)

Question 2

presentation of osteomalacai

Answer 2

Lower back pain
Bone pain in shoulder, ribs, pelvis or legs
Muscle pain and weakness, waddling gait (proximal myopathy)
Impaired physical function
Fractures especially femoral neck

Question 3

What is osteomalacia in children

Answer 3

Rickets

Question 4

Causes of osteomalacia

Answer 4

Vit D deficiency
Chronic kidney disease #Drug induced anticonvulsants
Inherited - hypophosphatemic rickets prev vit D resistant rickets
liver disease eg cirrhosis
Coealiac disease

Question 5

Investigations for osteomalacia

Answer 5

Bloods:
Low vit D levels
Low calcium, phosphate
Raised alkaline phosphatase
Xray - translcent bands - loosers zones or pseudofractures

Question 6

Treatment for osteomalacia

Answer 6

Vit D supplementation
Calcium supplementation if dietary caclium inadequate