OSPE drug dosage Flashcards

1
Q

osteoarthritis

A

tab.paracetamol500mg,9 tablets, 3x daily for 3 days
1% diclofenal gel
-3-4 times daily on pain knee

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2
Q

65-year-old woman, for the first time. She complains of pain in both her knees.
There is no swelling nor tenderness on both knees.
She has no other illness except that her BMI is 31 kg/m2.
You prescribe ibuprofen to Madam B.
What instruction and advice you will give to this patient?

A
  • She should take the tablet thrice daily after food for 3 days.
  • If she experiences any burning pain in the stomach or any allergic reaction
    like itching and skin rash, she should contact you immediately.
  • She should not continue the medication for more than 3 days without your advice
  • As the medicine gives only temporary relief, she should try to reduce her body weight which may be one of the reasons for her knee pain.
  • She should consult a physiotherapist for some knee exercise.
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3
Q

Toothache with h/o Peptic ulcer/
25yr,fever fr viral infection

A

Tab. Paracetamol 500mg
Dispense 9 tablets
Take one tablet thrice daily after food for three days.

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4
Q

musculoskeletal pain/severe body ache-tab.ibuprofen

A

400mg, 9 tablets

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5
Q

abdominal colic

A

Inj. Diclofenac 25mg/ml in 3ml ampule
Dispense one ampule
Inject 2ml deep intramuscularly over the upper and outer part of the gluteal region.

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6
Q

severe post operative pain

A

Inj. Morphine 10 mg/ml in 1ml ampoule I.M. to be repeated after 4 to 6 hrs. if pain persists.
Dispense 1 such ampoule

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7
Q

alternative for post operative pain

A

Inj. Tramadol 50mg/ml in 1- or 2-ml ampoule I.M. or I.V. Or

Inj. Ketorolac 30mg/ml in 1ml ampoule I.M

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8
Q

Paracetamol poisoning

A

explain mechanism
INj.N-acetyl cystein IV/oral methionine

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9
Q

dysmenorrhoea

A

Tab.mefenamic acid 250mg, dispense12 tabs,4x for 3 days

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10
Q

A 55-year-old man reported to the clinic with pain on both knees.
He has history of myocardial infarction and peptic ulcer.
The attending doctor prescribed him Celecoxib 200 mg once daily for 15 days. Comment on the prescription.

A

Celecoxib is selective COX2 inhibitor and can be prescribed for knee pain in patients with history of peptic ulcer.
But the patient also gave the history of myocardial infarction. Celecoxib is contraindicated in myocardial infarction because it prevents synthesis of PGI2 which is an action on COX2 but does not prevent synthesis of TXA2, an action on COX1. TXA2 produces vasoconstriction and aggregation of platelets whereas PGI2 produces vasodilatation and inhibits platelet aggregation.
Therefore, celecoxib should not be prescribed to this patient, instead paracetamol is a better option for this patient.

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11
Q

skin manifestations of food allergy

A
  • Tab diphenhydramine 25 mg
  • Dispense 15 tablets of diphenhydramine
  • Take 3 tablets once daily for 5 days
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12
Q

alternative for food allergy

A
  • Tab. fexofenadine 120 mg
  • Dispense 5 tablets of fexofenadine - Take 1 tab once daily for 5 days
  • Avoid taking sea food
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13
Q

mild microcytic hypochromic anaemia

A

Mild microcytic hypochromic anemia is treated with oral iron therapy. Parenteral iron therapy is indicated only when there is acute/chronic blood loss or GIT disorders where oral iron is not absorbed

Tab. ferrous sulphate 200 mg
Dispense 90 tablets
Take one tab three times daily for 1 month
Review after one month.
Not to skip meals and take the medication regularly

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14
Q

allergic rhinitis

A
  • Tab diphenhydramine 50 mg
  • Dispense 15 tablets of diphenydramine
  • Take 3 tablets once daily for 5 days
  • Avoid pollens and avoid being exposed to rain and cold weather without protection
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15
Q

acute severe migraine.

A

Tab. Sumatriptan 50 mg
Tab. Domperidone 10 mg
Dispense 5 tabs each of sumatriptan and domperidone Take 1 tab each at the onset of an attack
Repeat once within 24 hours if required

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16
Q

migraine prophylaxis

A

Tab. Propranolol 15 mg
Dispense 10 tabs of propranolol
Take one tablet twice daily for 5 days

17
Q

motion sickness

A

Greet the patient
* Take Promethazine tablet 30 min before the journey and repeat
after 8 h if needed
* You may experience sedation, blurring of vision and dry mouth
* Do not drive
* Avoid alcohol consumption

18
Q

pregnant,severe anaemia

A

refer book
Iron requirement (mg) = 4
4 ×body weight(kg) ×Hb deficit

Inj. Iron dextran 100mg/2ml ampule
Dr X Add:xxx Date:xxxx
Dispense 20 ampules
2ml injection deep IM everyday using the Z technique over the gluteal region To come to the clinic everyday for 20 days.
To continue folic acid.

19
Q

pregnant lady for the prophylaxis of anaemia

A

Tab. ferrous sulphate 200 mg
Folic acid 5 mg

Dispense 30 tablets each of ferrous sulphate and folic acid
Take one tab each of ferrous sulphate and folic acid once daily for 1 month Review after one month

20
Q

You prescribe tablet ferrous sulphate to a 17-year-old female patient suffering from microcytic hypochromic anaemia.instructions?

A
  • Greet the patient
  • Explain the purpose of taking ferrous sulphate tablets
  • Take a tablet ferrous sulphate 200mg three times daily after food for 1 month.
  • Come for review after one month.
  • You may develop nausea, vomiting, diarrhoea/ constipation or black stool
  • You may have allergic reactions. Consult a doctor if you experience such reactions
21
Q

oral B12 for pernicioius anaemia?

A

No.
Pernicious anemia is due to intrinsic factor deficiency. Intrinsic factor is required for the absorption of oral vitamin B12.
Oral vitamin will not be absorbed. Parenteral Vitamin B12 is needed.

22
Q

half life

A

0.693x VD/CL

23
Q

LOADING DOSE

A

CP X VD /F

24
Q

MAINTENANCE

A

CP X CL X DOSE INTERVAL IF PRESENT

25
Q

CP STEADY STATE

A

DOSING RATE/ CL

26
Q

ELIMINATION RATE

A

CLXCP

27
Q

Vd

A

Dose admin /Cp