AMA drugs

Question 1

cell wall synthesis:

Answer 1

beta lactams:
penicillins
cephalosporins
carbapenems
monobactams

vancomycin
bacitracin

Question 2

cell membrane

Answer 2

polymyxins

Question 3

folate synthesis

Answer 3

sulfonamides
trimethoprim

Question 4

DNA gyrase

Answer 4

quinolones

Question 5

RNA polymerase

Answer 5

Rifampin

Question 6

50 S RIBOSOME

Answer 6

macrolides
clindamycin
linezolid
chloramphenicol
streptogramin

Question 7

30 s ribosome

Answer 7

tetracyclines
aminoglycosides

Question 8

narrow spectrum antibiotics

Answer 8

active against a selected group of bacteria

Question 9

broad spectrum ab

Answer 9

active against wide range of of pathogens n may be used for variety of infections

Question 11

definitive therapy

Answer 11

use of antimicrobial agent aft identification of causative organism aft availability of susceptibility test results fr the laboratory

Question 12

empirical therapy

Answer 12

use of AMA b4 identification of causative organism n susceptibility test

Question 13

MIC

Answer 13

lowest antimicrobial con.c req to inhibit visible growth of the organism aft 24 hrs of incubation

Question 14

MBC

Answer 14

lowest conc antimicrobial req to kill the organism aft 24 hrs of incubation

Question 15

time dependant killing

Answer 15

the % of time the blood conc of a drug remains 4-5 times MIC

Question 16

Post antibiotic effect

Answer 16

persistent suppresion of microbial growth seen aft the antibiotic conc has fallen below the MIC