Osmoregulation Lecture 3 Flashcards

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1
Q

Is urea and TMAO compatible osmolytes?

A

Seperatly, no they are not. However put together they behave as compatible osmolytes.

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2
Q

Nephrons:

A

The excretory tubules called nephrons are located in a specialized organ called the kidney.

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3
Q

In all nonmammallian vetebrates the kidney produces urine that is either

A

hyposmotic or isoosmotic to body fluids with the exception of some birds being able to rpoduce urine that is a littler hyperosmotic.

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4
Q

Do the kidneys in fish play a significant role in regulation of salts?

A

No because they cannot produce hyperosmotic pee.

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5
Q

What part of the fish does play a big role in excretion of salt?

A

The Gills! there are specialized cells in the gills called called chloride cells which actively transport Cl into the sea. Na and K are also actively transported to maintain balance.

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6
Q

How are sharks and sting rays different to the small fish in salt excretion?

A

The osmolarity of their body fluids is maintained not by excreting salt out but by increasing concentrations of Urea and TMAO. Excess salts are excreted in the kidney and by specialized glands called rectal salt glands near the anus.

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7
Q

How do freshwater fish maintain osmolarity?

A

They are hyperosmotic to their environment. The excrete large quantities of dilute urine to get rid of excess water. Salt is replaced by eating it in foods and the active transport of Na, K and Cl from the gills. Nitrogenous watse is excreted by the gills as ammonia.

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8
Q

How do amphibians get salt?

A

They obtain salt from the water through active transport across their skin.

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9
Q

How do reptiles conserve water?

A

The scales covering their body allow almost no water to be lost this way.

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10
Q

How do birds and and reptiles that live around sea water excrete salt?

A

Through specialized salt glands located in the head that remove salts from the blood by active transport. Excreted in a solution that is 2 or 3 times higher than the salt body fluids.

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11
Q

Marine osmoregulators (salt water fish) are what to their environment?

A

Hypo-osmotic

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12
Q

Therfore how do they get water?

A

Maintain water balance by drinking water!

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13
Q

Freshwater osmoregulators are what to their environment?

A

Hyper-osmotic.

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14
Q

Do fresh water fish drink water?

A

No! They do not need to!

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15
Q

In marine fish we have to pump ions out to account for the ions moving in with the water that they have to drink. What generates the membrane potential? What does the cause the inside of the chloride cell to become?

A

3 Na going out and 2 K going in creates a membrane potential. This causes the inside of the cell to become negative.

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16
Q

How does chloride exit?

A

Through the CFTR channel.

17
Q

What causes K to be pushed out?

A

The cell being negative pushes K out.

18
Q

What causes Na to be pushed out?

A

As K+ leaves this causes the cell to become even more negative which then pushes Na out!

19
Q

How are salmon different?

A

They alternate between modes of osmotic adaptation.

20
Q

What happens when salmon enters the ocean?

A

cortisol triggers growth of seawater type chloride cells in gills which then reverses the direction of ion transport and increases Na/K ATPase

21
Q

What happens when salmon return to freshwater?

A

Prolaction stimulates return to freshwater type chloride cells and this again reverses the direction of ion transport.

22
Q

In the salt glands of birds and reptiles what type of transport is there?

A

Active NaCl transportt

23
Q

What is the kidney most concerned with?

A

Osmoregulation.

24
Q

There are four steps as the fluids goes through the tubule.

A
  1. Filtration
  2. Reabsorption
  3. Secretion
  4. Release
25
Q

Describe filtration:

A

small molecules and ions from the body fluids or blood nonselectively pass through narrow spaces between cells into the tubule.

26
Q

Describe Reabsorption:

A

Nutrient molecules, some ions and conserved water are returned to the body fluids or blood by transport epithelium.

27
Q

Decsribe Secretion:

A

Excess ions and toxic breakdown products are transported selectively from the body fluids or blood into the tubule.

28
Q

Decsribe Release:

A

Urine is released into the environment.

29
Q

Filtration is the first step and leads to primary urine. What two different mechanisms lead to primary urine?

A

Ultrafiltration and Active secretion

30
Q

What is the most important route for eliminating substances from the body fluid or blood.

A

Filtration is the most important route followed by secretion.

31
Q

Malpighian tubule system:

A

is a type of secretory and osmoregulatory system,