OSCE Peer Teachings Flashcards
What is MJ-THREADS
MI Jaundice - TB HTN Rheumatic fever Epilepsy Asthma and COPD Diabetes Stroke
Relevant things to ask about for FHx
Atopy, autoimmune, MI
What should you ask about in asthma
Pets
Cardiac presenting complaints
Chest pain SOB Ankle swelling Cough, sputum, haemoptysis Dizziness Syncope Palpatations Claudications
Cardiac causes of chest pain
MI Pericarditis Angina AF Acute myocarditis Aortic dissection
Musculoskeletal causes of chest pain
Costocondritis
Trauma
Muscle sprain
Gastrointestinal causes of chest pain
GORD
Peptic ulcer disease
Oesophageal stricture
Respiratory causes of chest pain
PE
Pneumonia, TB
Pneumothorax
Malignancy
Other causes of chest pain
Anxiety
Sickle cell crisis
Shingles
SOCRATES
Site Onset Character Radiation Associated symptoms Timing Exacerbating/alleviating factors Severity
MI SOCRATES
Central, crushing, radiates down left arm and jaw
Perciarditis SOCRATES
Central pain, bores through to the back, better if sat forward. Worse if lying down.
Angina SOCRATES
Central tightness or heaviness, radiates to arms and jaw. Exertional! Relieved by rest!
Acute myocarditis SOCRATES
Preceding flu symptoms
Aortic dissection SOCRATES
Tearing pain, central or abdominal
MI more likely to be silent in
Diabetics
Cardiac associated features
Syncope, epigastric pain, vomitting
What is a significant cardiac family history
MI <55yo 1st degree relative
What should you ask about PC
Whats your main concern? Which symptom is most problematic?
What medical conditions can cause angina
Anaemia, thyrotoxicosis, hyperlipidaemia and aortic stenosis.
How to distinguish between stable and acute angina
Stable=exertional
Quantify exertion
Cold, emotion, heavy meals.
How frequent? How is it affecting them? How do you stop the pain? New Dx?
Associated symptoms, lifestyle, PMH
What specific history questions might you want for angina
Statin?
GTN?
Aspirin?
Past MI?
Non modifiable cardiac risk factors
Male, age, familly history of IHD
Modifiable risk factors
Smoking, hypertension, hyperlipidaemia, obesity, sedentary lifestyle
Define acute angina
Chest pain at rest >20 minutes and associated symptoms
What are ACS
Acute angina and MI
Questions for SOB
Onset Pattern Affect on daily life? Quantify PMH DH Wheeze, weight loss, swelling
PMH questions for SOB
Asthma, malignancy, CV history, anaemia
Associated symptoms questions for SOB
Wheeze, weight loss, swelling
Differentials for SOB
Heart failure, PE, resp stuff
Symptoms fo LV failure
Dyspnoea, PND, Orthopnoea, poor exercise tolerance, fatigue, cough, wheeze
Define dyspnoea
Shortness of breathe
Define orthopnoea
SOB on lying flat
Define Paroxysmal Nocturnal Dyspnoea
SOB at night, waking from sleep
What classification is used for HF severity
New York Association Classification
SOB questions
What was normal before diagnosis? Quantify activity. Pillows at night? Stairs?
Grade I HF
No limitations, no symptoms on activity
Grade II HF
Rest fine, activity causes symptoms
Grade III HF
Marked limitation of physical activity
Grade IV HF
Symptoms at rest and any activity
What does peripheral swelling suggest
Right ventricular heart failure
Signs of RV heart failure
Pitting oedema, sacral oedema, ascites, nausea, facial engorgement, anorexia
What does cough with pink frothy sputum suggest
LV failure
RV failure = cough?
Lung disease a cause so possibly
What does nocturnal cough suggest
Asthma or heart failure
What does haemoptysis suggest
PE and malignancy
Questions for palpitations
Frequency Onset Duration 'Desribe it' Tap out rhythm Dizziness or LOC Anxiety Hx
Palpitations PMH
AF diagnosis
On any blood thinners
Stroke or mini stroke?
History of valve disease?
What is CHADS2VASC for
Atrial fibrillation stroke risk
What does CHADS2VASC stand for
Congestive HF HTN Age (65-75-+) DM Stroke, tia Vascular disease Sex: female
What risk score is used for risk of bleeding on warfarin
HTN Abnormal liver or kidney Stroke Bleeding Labile INR Elderly Drugs or alcohol
Causes of syncope
Postural hypotension, vasovagal attack, severe aortic stenosis, AF
Syncope questions
When? How often? Blackouts? Associated symptoms? Systems review
Syncope associated symptoms
Palpitations, sweating, hyperventilation, chest pain, headache
Intermittent claudication questions
SOCRATES Where Quantify Risk factors Associated symptoms
Calf intermittent claudication artery
Femoral
Buttock intermittent claudication artery
Iliac
Intermittent claudication risk factors
Smoking, alcohol, diabetes, hypertension, hyperlipidaemia
Intermittent claudication associated symptoms
Gangrene, burning, foot pain, impotence
“Im hanging my foot off the bed at night”
Critical limb ischaemia.
Pacemaker v ICD
ICD can directly treat the arrythmia whereas a pacemaker just provides electrical stimuli
Describe aortic stenosis
Ejection systolic murmur heard loudest over aortic region. Can radiate to carotids. Loudest when sat forward in held expiration.
Describe mitral regurgitation
Pansystolic murmur loudest in axilla.
Causes of aortic stenosis
Old age calcification
Causes of mitral regurg
IV hypertrophy, IE, Valve calcification
Cough questions
Duration Dry or productive? Sputum Blood Time of day? Exacerbations
Cough: Sputum questions
Consistency
Colour
Odour
Cough: Blood questions
How much?
Fresh or old?
Bleeding elsewhere?
DVT symptoms?
Cough: Exacerbation questions
Pets Pollen Dust Weather Occupation
Cough: other important symptoms
Wheeze Chest pain SOB FEVER, WEIGHT LOSS, NIGHT SWEATS feel unwell
Cough PMH
Acid reflux
Asthma
COPD
TB
Cough DHx
ACE inhibitors
Allergies
Inhalers
TB Jab
Cough FHx
Asthma, hayfever, eczema
Pneumonia contacts
TB contacts
Cough SHx
Occupation Pets Smoking Pollution Foreign travel
General respiratory PMH
TB Asthma PE Pneumonia GORD Allergies Rheumatoid
General respiratory FH
Cystic fibrosis TB Asthma Eczema Hayfever Emphysema
General respiratory SH
Crowded accomodation Damp Occupation Foreign travel Pets
SOB HPC
Describe Duration Constant or intermittent Activity limitation? Getting worse? Any exacerbations? Any relieving factors?
SOB Other symptoms
Chest pain Lie flat Pillows PND Ankle swelling Wheeze Cough Systemic illness Anxiety and pain attacks Fatigue
SOB PMH
Asthma COPD TB Cardiac Severe lung infections Blood clot
SOB DH
Inhalers
Allergies
SOB FH
Asthma
Cardiac disease
SOB SH
Smoking and ex smoking
Occupation
Stress and anxiety
Asthma assessment
Symptoms Waking at night Symptoms in morning Reliever use Activity limitation Allergies Social
Asthma symptoms
Wheeze Cough SOB Infections Diurnal variation
Asthma SHx
Coping with medications
Smoking
Occupation
Pets
GTN side effects
Low blood pressure
Dizziness
Name the two open questions to ask first
Please could you tell me whats been troubling you?
Can you tell me more about this?
Important questions about PC
SOCRATES
Have you had this before?
What do you think might have caused it?
Special question for dyspepsia
Can you describe the sensation of indigestion that you feel
Causes of dyspepsia
Peptic ulcer
GORD
Gastritis and duodenitis
Non ulcer dyspepsia, medication induced and non GI
Which type of peptic ulcer is more common
Duodenal
Describe gastric ulcers
Less common Pain caused by meal Occurs 30mins-1hr after meal Bleeding- haematemesis Caused by delayed gastric emptying
Describe duodenal ulcers
More common Pain relieved by eating Occurs 2-3 hours after meal Bleeding- melaena Caused by increased gastric emptying
How to take a dyspepsia HPC
SOCRATES and ALARMS symptoms
Whatre you thinking about with the radiation of dyspepsia
Perforation? Pancreatitis? Chest pain- cardiac
Associated symptoms with dyspepsia
Bitter taste (GORD)
Early satiety?
Bloating
ALARMS red flags
What are the ALARMS dyspepsia red flags
Anaemia (iron deficiency) Loss of weight Anorexia Recent onset/ progressive Malaena/ haematemesis Swallowing difficulty
If the dyspeptic patient has one of the ALARM symptoms or is over 55
Upper GI endoscopy
In addition to SOCRATES what should you ask a dyspepsia patient
Have you had these symptoms before? How does this episode compare? Do you know what may have caused these symptoms?
Vomitting and dyspepsia
Haematemesis, bleeding peptic ulcer, gastric cancer in the pyloric region
Malaena and dyspepsia
Due to erosion of mucosa due to gastric cancer or bleeding peptic ulcer
Dyspepsia and weight loss
How much? In how long? Suggests malignancy
Dyspepsia and tiredness/SOB
Chronic disease, leading to anaemia
Relevant Drug history for dyspepsia
NSAIDs/ Aspirin, steroids, SSRIs
What is dysphagia
Difficulty swallowing
What is odynophagia
Painful swallowing
What is globus
Sensation of having a lump in the throat
What is new onset dysphagia in middle age and elderly people
Cancer until proven otherwise
What is high dyphagia
Oropharyngeal and upper oesophageal
What is low dysphagia
Lower oesophageal
Character in dysphagia SOCRATES
Solids, liquids or both? has this changed?
Associated symptoms in dysphagia SOCRATES
Regurgitation? Neck lump? odynophagia?
Questions to ask about relieving factors in dysphagia SOCRATES
Does it get better after the first few swallows
Other questions to ask about dysphagia on top of SOCRATES
Have you had these symptoms before? How does this episode compare? Do you know what may have caused these symptoms?
Other PC to ask about in dyspepsia
Dysphagia Vomiting Abdo pain/ bloating Jaundice Constipation Blood in stool Weight loss Tiredness/ SOB
Other PC to ask about in dysphagia
Dyspepsia Vomiting Abdo pain Jaundice Change in bowel habit Blood in stool Weight loss
Young person diarrhoea causes
Infective diarrhoea
Irritable bowel syndrome
-coeliac, crohns, UC, medications, hyperthyroid
Old person diarrhoea causes
Neoplastic (colon or pancreatic) Diverticular disease Overflow Medications IBD
Which ages are most affected by IBD
15-25years and also 50-80years
Which patients are at risk of bacterial overgrowth
Diabetic patients
7 questions to ask about the character of
1- frequency 2- colour 3- formed or watery 4- blood? paper? mixed? 5- float? flushable? 6- smelly? 7- mucus
What do stools which float, are difficult to flush and offensive smelling suggest
Steatorrhea
Causes of steatorrhoea
Chronic pancreatitis and malabsorption
What are gauges of severity in diarrhoea
Urgency to go to the toilet, incontinence
What should you always ask on top of SOCRATES
Have you had these symptoms before? How does this episode compare? Do you know what may have caused these symptoms
What does diarrhoea and vomitting suggest
Gastroenteritis
What GI associated symptoms should you ask about in diarrhoea
Vomiting Abdominal pain Jaundice Constipation Blood in the stool Weight loss Fever, tiredness, SOB -dyspepsia and dysphagia
What should you ask about if constipation and diarrhoea
Altered bowel habit? Tenesmus
What does weight loss and diarrhoea suggest
IBD, Carcinoma
What does fever, tiredness and SOB associating diarrhoea suggest
Chronic disease accompanying
Other presenting complaints to ask about in diarrhoea
Uveitis, scleritis, episcleritis
Rashes
Joint pain
Thyroid symptoms (feel hot, palpitations, weight loss)
Risk factor questions for diarrhoea
Recent foreign travel Eaten anything unusual Unwell contacts with similar symptoms Stress? Diet? Changes to meds?
Diarrhoea- general examination
Jaundice, signs of dehydration, signs of anaemia
Diarrhoea- hand examination
Clubbing
GI/ diarrhoea causes of clubbing
IBD
Hyperthryoid
Coeliac
Diarrhoea- eye examination
Iritis, episcleritis,
How to distinguish episcleritis and scleritis
Episcleritis is more localised whereas scleritis can be blue
Diarrhoea- mouth examination
Mouth ulcers
Diarrhoea- lymph examiation
Virchows node
Diarrhoea- abdomen examination
Masses, tenderness, bowel sounds
Diarrhoea- leg examination
Rashes
In a history should you ask age or DOB first
Age
MSK presenting complaints
Pain Stiffness Swelling Erythema Weakness Extra-articular symptoms
Questions about an MSK presenting complaint
SOCRATES
Have you ever had this before?
What do you think might have caused it? Trauma?
Questions about other presenting complaints in an MSK history
Extra-articular features
Risk factors for diseases
PC of other systems
MSK- Site, queries
Arthralgia, myalgia, soft tissue?
small or large joint?
Mono, Oligo, Poly?
Symmetrical, haphazard?
MSK- Onset, queries
Post trauma
Gradual onset
Acute onset
MSK- Post trauma onset
Haemarthrosis
Tendon tear
Tendonitis
MSK- Gradual onset
OA
RA
Chronic injury
MSK- Acute onset
Gout
Vacular aetiology
Trauma
OA joint distribution
Neck Spine Hip Distal fingers Knee
RA joint distribution
Neck Shoulder Elbow Wrist Every hand joint Hip Knee Ankle Every foot joint
Psoariatic arthritis joint distribution
Elbow Wrist Fingers Knee Ankle Toes
Ankylosing spondylitis joint distribution
Spine
Pelvis
Knee
MSK: Deep, boring pain esp at night
Osteomyelitis, osteonecrosis, bone mets
MSK: Diffuse pain
Osteomalacia
Fibromyalgia
MSK: Stiffness, poorly localised pain, worse on movement. Muscle pain
Polymyositis
Dermatomyositis
Partial muscle tears
MSK: Sharp pain worse on movement
Fracture pain
MSK: Shooting pain (peripheral nerve/root impingement)
Disc prolapse
Sciatica
MSK: Widespread unremitting pain, poorly controlled
Fibromyalgia, complex pain syndrome
MSK: Exquisite pain but no apparent abnormality
Compartment syndrome
MSK: Wells criteria
Clinical signs of DVT PE more likely than alternative Immobilised 3 days Previous DVT or PE Haemoptysis Active malignancy
MSK: Nerve compression radiation
Radiates to the nerve distribution
MSK: Neck pain radiation
Radiates to the shoulder and over the top of the head
MSK: Low grade fever
SLE
RA
Giant cell arteritis
MSK: Spiking fever
Septic arthritis
Bone TB
Osteomyelitis
MSK: Spiking fever and pain which moves from joint to joint
Rheumatic fever
Gonococcal arthritis
MSK: Weight loss
Malignancy
Bone METs
Systemic (SLE, RA)
MSK: extra articular features
Rash Malaise Jaw claudication Headache Diarrhoea & GI Eye involvement
MSK: Timing questions
How often?
For how long?
Is there a pattern?
MSK: early morning stiffness and pain which lasts more than 30mins
Rheumatoid arthritis
MSK: end of the day aches and pains
Osteoarthritis
MSK: Stiffness which improves on exercise in younger patients
AnkSpond
MSK: Suggested exacerbating factors
Cold weather Physical exertion Infection Immobility Certain foods (alcohol)
MSK: Suggested alleviating factors
Warmth
Exercise
Resting
NSAIDs
MSK: Very severe pain
Trauma
Gout
Septic arthritis
Vascular
MSK: Severity questions
Scale 1-10
Stop you doing things?
Affect social/work?
Wake you up?
MSK: Stiffness questions
Restricted ROM?
Difficulty moving but normal ROM?
Painful movement? Particular joint or generalised movements?
MSK: Inflammatory stiffness
Early morning, more than 30mins, wears off with activity, responds well to NSAIDs
MSK: Non inflammatory stiffness
Mechanical, stiffness after rest but lasting less than 30mins. End of day stiffness and tiring
MSK: Polymyalgia rheumatica stiffness
Shoulder and pelvic areas. Temporal arteritis associated. Jaw claudication, temporal pain, vision symptoms. GIVE STEROIDS
MSK: AnkSpond stiffness
Back stiffness on waking up
MSK: Unilateral swelling
Local cause
MSK: Bilateral/symmetrical swelling
Systemic cause
MSK: Sudden onset swelling
Vascular, acute injury
MSK: Gradual onset swelling
Chronic injury or inflammation
MSK: swelling DHx
Anticoagulants? Bleeding disorder?
MSK: Erythema and warmth
Infective arthritis
Trauma
Foods which cause gout
Anchioves
Fish
Kidney, liver
Yeast (beer)
Foods which prevent gout
Lemon Cherries Peppers Watercress Ginger Tumeric
What are gout crystals made out of
Uric acid crystals
What are pseudogout crystals made out of
Calcium pyrophosphate
Which gender gets more gout
Males
Which gender gets more pseudogout
Females
Gout on light microscopy
Negatively birefringent needles
Pseudogout on light microscopy
Positively birefringent rhomboids
Which joints are affected by gout
1st MTP, small joints of hand, wrist, ankle, elbow, knee
Which joints are affected by pseudogout
Knee, wrist and ankle
Which other changes are associated with gout
Purine rich foods, obesity, DM, crystal cellulitis, gout tophi, urate kidney stones
Which other changes are associated with pseudogout
Fever, chondrocalcinosis on XRay
MSK: Neurological causes of weakness
Spinal cord injury Nerve root entrapment Single nerve damage MND GBS Polio
MSK: Muscular causes of weakness
Myositis
Myalgia
Muscle atrophy
Causes of myositis
Injury
Infection
Autoimmune
Causes of muscle atrophy
Malnutrition Burns Muscular dystrophy Drug SEs LMN damage
Infective causes of myalgia
Coxsackie virus Cytomegalovirus Dengue fever Streptococcus Mycoplasma
Trauma causes of myalgia
Tears
Haematoma
Rhabdomyolysis
Inflammatory causes of myalgia
Polymyalgia rheumatica
Dermatomyositis
Polymyositis
Drugs causes of myalgia
Alcohol withdrawal
Statins
Triptans
Metabolic causes of myalgia
Hypo/hyperthyroid
Addisons disease
Low vitamin D
Myotoxic drugs
Colchicine Antimalarial Statins Corticosteroids Sulfonamides Zidovudine
MSK: Past medical history
Previous MSK
TB
Gout
Risk Factors
MSK: PMH Risk Factors
DM Coeliac Steroid therapy Fractures or deformities Stroke
MSK: Gout PMH questions
Alcohol
Renal disease
Metabolic syndrome
Aspirin, diuretics
MSK; Family history
Inflammatory arthritis (1stDegree) OA/osteoporosis HLA-B27 Charcot Marie Tooth Osteogenesis imperfecta Ehlers-Danlos, Marfans Muscular dystrophies
4 HLA-B27 seronegative conditions
PEAR Psoariatic arthritis Enteropathic arthritis Ank Spond Reactive arthritis
MSK: Drug history
Steroids Statins ACE-I Anti epileptics Immunosuppressants Quinolones
MSK: what do steroids cause
Osteoporosis
Myopathy
Osteonecrosis
MSK: what do statins cause
Myalgia, myositis, myopathy
MSK: what do ACE-I causee
Myalgia
Arthralgia
MSK: what do anti-epileptics cause
Osteomalacia
Arthralgia
MSK: what do immunosuppressants cause
Infections: Osteomyelitis
MSK: what do quinolones cause
Tendinopathy, tendon rupture
MSK: Social history
Occupation Ethnicity Sexual History Alcohol Smoking IVDU Diet
MSK: occupational diseases
Repetitive strain disorder
Hand vibration syndrome
Fatigue syndrome
MSK: Ethnicity diseases
African- sickle cell
Asian- osteomalacia
TB areas- bone TB
MSK: Sexual diseases
HIV- reactive arthritis, gonoccal arthritis
Neurosyphilis
Hep B
MSK: Alcohol diseases
Trauma Gout Myopathy Rhabdomyolysis Neuropathy
MSK: Smoking diseases
Lung cancer bone mets
RA
MSK: IVDU diseases
Trauma
Hep B
HIV
MSK: Diet diseases
Vitamin deficiencies
-rickets/osteomalacia
-scurvy
Osteoporosis
MSK: Extra-articular features
Brain Hair Eyes Mouth Face/skin Nail changes Skin rash Dry cough/ SOB Arrythmias Abdominal pain Aches/ weakness Hand deformities
MSK: brain signs
SLE= depression&migraines Fibromyalgia= tension ha GCA= throbbing ha + vision loss
MSK: hair signs
SLE= scarring allopecia
Dry? Brittle?
MSK eye signs
Sjogrens= red and dry Episcleritis= pain & tearing Uveitis= pain & floaters
MSK: mouth signs
Crohns&SLE= sores Sjogrens&RA= dry
MSK: face
Sarcoidosis= lupus pernio SLE= malar rash Sjogrens= big salivary glands
MSK: arrythmias
SLE= endocarditis
Scarring and cardiomyopathy
MSK: dry cough/sob
Sarcoidosis
SLE
Caplans
MSK: Aches and weakness
PMR
Steroids
Sjogrens
Dermatomyositis
MSK: Abdominal pain
SLE= serositis
Sarcoidosis= high Ca2+
Fibromyalgia= IBS
Enteropathic A= IBD
MSK: Nail changes
Psoariatic arthritis= nail pitting
MSK: Skin rash
Erythema Nodosum
TB, Sarcoidosis
SLE= photophobia
Osteoarthritis XRay signs
LOSS Loss of joint space osteophytes Subchondral cysts Subarticular sclerosis
MSK: DIPJ
OA (Heberdens)
Psoariatic
Reactive
MSK: PIPJ
OA (Bouchards)
SLE
RA
Psoariatic
MSK: MCP
RA
Pseudogout
Haemochromatosis
MSK: Base of thumb
OA
MSK: Wrist
RA Pseudogout JIA Carpal tunnel Gonococcal arthritis
HLA DR4
RA DM1 MS Coeliac SLE IgA nephropathy Systemic sclerosis PMR
HLA B27
P E A R
HLA DR2
Goodpastures SLE MS PBS AI Hepatitis
Vitiligo associations
Hashimotos Scleroderma RA DM1 Pernicious anaemia Addisons SLE
Signs of goodpastures syndrome
Haematuria and haemoptysis
Lower back pain red flags
Urinary retention
Saddle anaesthesia
Leg weakness
Faecal incontinence
What does having all the lower back pain red flags point towards
Cauda equina syndrome
Lower back pain questions
Cancer Hx Coeliac IVDU Morning stiffness Pseudoclaudication Trauma Fever <35yo
Fibromyalgiadditional questions
Chronic widespread pain Shoulders, elbows and knees Tension headache Atypical chest pain IBS Dysmennorhoea Facial pain Sleep disturbance
AnkSpond Clinical picture
Younge male Stiff pack better with exercise Night pain Sacroiliac joint Bamboo spine Reduced chest expansion Syndesmophytes Ankylosis Schobers test Uveitis+costohondritis
Psoariatic arthritis clinical picture
DIP Arthritis mutilans penicl in cup deformity Nail changes Dactylitis Enthesitis
What is arthritis mutilans
Periarticular osteolysis and bone shortening seen in psoariatic A
What is dactylitis
Whole digit swelling
What is enthesitis
Tendon attachment inflammation
What nail changes are in psoariatic arthritis
Subungal hyperkeratosis
Nail plate pitting
Discolouration and ridging
Onycholysis
Reactive arthritis develops after
UTI
STI
Dysentry (salmonella, shigella)
Reactive arthritis clinical picture
Conjunctivitis
Arthritis
Skin changes
-keratoderma blennorrhagica
Reiters syndrome
Cant see
Cant pee
Cant climb a tree
Rheumatic fever criteria
Jones criteria
Jones criteria for rheumatic fever
Joint arthralgia CardiOmyopathy subcutaneous Nodules Erythema marginatum Sydenham chorea
Dermatomyositis blood tests
ANA
CK
Myoglobin
Dermatomyositis clinical picture
Heliotrope (eyelid) rash V neck rash Gottons papules Periungal erythema Calcinosis
Causes of peripheral neuropathy
DM Poliomyelitis Chronic alcoholism Leprosy Syphilis
Neck of femur fracture sign
Leg shortened and externally rotated
Symptoms to screen for in a neuro history
Headache/ facial pain Weakness Numbness Collapse Confusion Gait change Tremor Dizziness Visual change
thunderclap headache is suggestive OF
SAH
What can focal neurological signs suggest
Brain haemorrhage
Stroke
Abscess
What can a change in mental status suggest
Raised ICP
Encephalitis
What is the triad of meningism
Photophobia
Neck stiffness
Headache
What can cause meningism
Meningitis
Abscess affecting meninges
SAH
What goes red eye suggest
acute closed angle glaucoma
What does worse on lying down suggest in a neuro patient
Raised ICP
What are causes of raised ICP
Space occupying lesion
Haemorrhage
What are red flags in neuro
Thunderclap headache Focal neurological signs Change in mental status Meningism Worse on lying down
Primary headaches
Tension
Migraine
Cluster
Secondary headaches
Intracranial infections
Intracranial bleeds
Raised ICP
GCA
Signs of tension headache in a history
Band like
Stressed
Towards end of day
Signs of a migraine headache in history
Unilateral Throbbing/ pulsating Aura Photophobia Phonophobia (Quiet dark room)
What is the most common aura in migraines
Scintillating scotoma (spot of flickering light)
Signs of a cluster headache in a history
Unilateral red eye
Autonomic features
Seasonal clusters
What are extra features of a cluster headache
Lid swelling
Lacrimation
Rinorrhoea
Questions to differentiate secondary headaches
Fever
Head injury/fall
Speed of onset
Meningitis symptoms
Neck stiffness Headache Photophone Fever N+V Non blanching rash
Diagnosis of meningitis
Blood cultures
Lumbar puncture
Treatment of meningitis in GP
IM BenPen
Treatment of meningitis in hospital
IV Cefotaxime
Specific signs for inflammation of lining of brain
Kernigs and Brudzinskis
Triad of encephalitis
Fever
Headache
Change in mental state
How to differentiate encephalitis and meningitis
Encephalitis has more predominant symptoms of confusion and altered consciousness
What is meningitis (layman)
Inflammation of lining of brain
What is encephalitis
Inflammation of brain parenchyma itself (Normally herpes, simplex bad)
Diagnosis of encephalitis
Lumbar puncture
Treatment of encephalitis
IV acyclovir
SAH symptoms
Thunderclap headache Raised ICP -headache -N&V -visual disturbance -fixed dilated pupil
SAH history
Usually spontaneous
Sentinel headaches
SAH PMH
PKD
Ehlers Danlos
SAH investigations
CT
SAH treatment
Endovascular coil, surgical clip
SDH history
Elderly
Alcholic
Recent major trauma
Within hours
Question to rule out brain tumour
Weight loss
Question to rule out brain abscess
Fever
Question to rule of intracranial bleed
Trauma
Symptoms of raised intracranial pressure
Headahce worse lying down/coughing
Weakness
N&V
Confusion
Describe what happens in GCA
Inflammation of branches of external carotid artery. Granulomatous thickening and reduced blood supply to distal muscles causes claudication
Signs of PMR
Shoulder and pelvic girdle pain and stiffness
Specific question in PMH for GCA
Polymyalgoa rheumatica
Specific questions for GCA
Hurt when comb hair?
Hurt when eat?
Vision problems?
Chest pain to back?
Symptoms of GCA
Jaw and tongue claudication
Tender scalp/ occiput
Sudden painless unilateral LOV
Aorta dissection risk
Investigation of GCA
Temporal artery biopsy
Treatment of GCA
High dose steroids
Differential diagnosis of visual disturbance
Migraine MS GCA Raised ICP Myasthenia gravis
Visual disturbance HPC questions
Describe what problem is
Onset
Ever had before
Associated symptoms
Possible descriptions of visual disturbance
Spot of flickering light in centre of vision which enlarges
Loss of central colour vision
Vision is blurry
Seeing double
Recurring visual problems suggests
MS
Migraines
Visual disturbance associated symptoms
Weakness
Numbness
Headache
MS investigations
LP- Oligoclonal bands
VEP- Optic neuritis
MRI
MS Treatment
Relapses- prednisolone
DMAs- beta interferon
What is often first presentation of MS
Optic neuritis
What does optic neuritis present as
Pain on eye movement
Reduction in central vision
Reduction in colour vision
Questions for MS
Disseminated in space and time Weakness? Sensory disturbance? Ever had before? Where? Fatigue? Worse in bath?
What is the pathophysiology of trigeminal neuralgia
Artery compressing trigeminal nerve and its branches
Questions to ask for trigeminal neuralgia
SOCRATES
Triggers- chewing, contact, breeze
Treatment for trigeminal neuralgia
Carbamazepine
Triggers of trigeminal neuralgia
Chewing, any contact, a breeze
Questions to ask about weakness
Site and distribution Onset Duration Triggers Timing and progression Associated symptoms Happened before?
Associated symptoms for weakness
Visual, speech and sensory disturbance. Bladder bowel, ED, saddle anaesthesia
Weakness PMH
Cardiovascular events
AI disease
Sudden onset weakness questions- currently?
Facial weakness? sensation? Visual disturbance? Weakness or sensory distribution elsewhere? Eating, drinking, swallowing problems? Speech disturbance? Dizziness/balance problems? Confusion?
Sudden onset weakness questions- in the past?
Head trauma
LOC
Illness
Anything similar
Bells palsy symptoms
Cant wrinkle brow Drooping eyelid Cant puff cheeks Drooping mouth Loud noises (stapedius)
Which cranial nerve is affected in Bells Palsy
CN VII Facial
What is the treatment for Bells Palsy
Prednisolone
Stroke- face, arm or leg symptoms
Numbness or weakness
Trouble walking
Stroke- brain symptoms
Confusion
Aphasia
Dizziness
Headache
Stroke- eye symptoms
Trouble seeing
Stroke- stomach symptoms
Nausea or vomiting
Is a stroke painful
No
Stroke history
Neuro and CVS Hx
CVS risk factors
Previous TIA
Stroke, CVS risk factors
HTN
DM
Cholesterol
AF
Stroke drug history
Anticoagulants
Stroke investiagtions
CT head
Stroke treatment
Streptokinase <4.5hrs
Aspririn >4.5hrs
Is weakness present in upper or lower motor neurone lesions
Both
Is atrophy present in upper or lower motor neurone lesions
Lower
Are reflexes and tone increased or decreased in UMN lesions
Increased
Are reflexes and tone increased or decreased in LMN lesions
Descreased
Are fasciculations present in UMN or LMN lesions
Lower
Is Babinski present in UMN or LMN lesions
Upper
Brain UMN lesions
Stroke
Space occupying lesion
Multiple sclerosis
Spinal cord UMN lesions
Multiple sclerosis
Spinal cord compression
LMN lesions
Radiculopathies
Peripheral neuropathies
Myasthenia Gravis
Guillain Barre Syndrome
Both Upper and Lower lesions
Motor neurone disease
Lesions disseminated in time and space
Multiple sclerosis
Symptoms made worse by hot baths
Motor neurone disease
What is a radiculopathy
Nerve root neuropathy
Causes of radiculopathy
Prolapsed disk Spinal stenosis Tumours Trauma Infection Spondylolithesis
What is the main cause of radiculopathy
Prolapsed disk
What is radicular pain
Pain along a dermatome
What is the general presentation of a radiculopathy
Sciatica
LMN weakness and altered sensation
Absent reflex
Bladder, bowel, ED, saddle anaesthesia
What is myelopathy
Spinal cord compression
What is the most common cause of myelopathy
Metastasis
What are the causes of myelopathy
Metastasis, infection, trauma, disk prolapse
Chronic subacute spinal cord compression presentation
Spastic paraparesis
Radicular pain at level
Sensory loss below level
What would the radicular pain be if you had spinal cord compression at T4
Band of pain around nipples, worse on coughing or straining
What would the sensory symptoms be in spinal cord compression
Numbness starts in the feet and then rises to level of compression
What does spastic paraparesis show as
Retention of urine and constipation develops
Does cauda equina syndrome show UMN or LMN signs
LMN
Red flags for cauda equina syndrome
Sever lower back pain Sciatica Bladder/bowel dysfunction, urinary retention Saddle anaesthesia Sexual dysfunction Neurological deficit in lower limb
Motor neurone disease signs
UMN/LMN signs, no sensory loss
MND History hints
Weakened grip, dropping things
Shoulder weakness
Tripping up
Dysarthria (bulbar onset)
How does myasthenia gravis work
Autoantibodies against post synaptic ACh receptor at the NMJ
Age and gender of myasthenia gravis
20-40, women more than men
What are classic signs of MG
Eye muscle weakness, fatigueability
What is the progression of MG
Eye, bulbar (dysphagia, swallowing, chewing, dysarthria) then proximal limb muscles
Questions to ask in MG history
Symptoms get worse as day goes on?
Exacerbated by exertion?
Numbness and tingling red flags
Weakness Incontinence Saddle anaesthesia Numbness after trauma Confusion Drowsiness
What does incontinence suggest when accompanying numbness
Cauda equina
What does saddle anaesthesia suggest when accompanying numbeness
Cauda equina
What does numbness after head, neck or back injury suggest
Spinal injury
- cord compression
- cauda equina
- nerve root compression from prolapsed disk
What does confusion and numbness/tingling suggest
Stroke/something else affecting the brain
Numbness and tingling sites
Dermatomal Non dermatomal Sensory level One side of the body Hands and feet
What dos dermatomal distribution suggest
Peripheral nerve or nerve root lesion
What does a sensory level distribution suggest
Spinal cord lesion
What does a one side of the body distribution suggest
Stroke or other brain lesion
What does a glove and stocking distribution suggest
Peripheral neuropathy
Which nerve controls biceps muscle
C6
Which nerve controls big toe extension
L5
Radiculopathy specific questions
What were you doing at the time
Carpal tunnel syndrome tell tale sign
Thumb weakness
Carpal tunnel syndrome risk factors
Rheumatoid arthritis
Hypothyroidism
Ulnar nerve compression questions
Trauma to elbow
Weakness of hand muscles
Radial nerve compression question
Cannot open first
Median nerve muscles
LLOAF Lateral 2 lumbricals Opponens pollicis Abductor pollicis brevis Flexor pollicis brevis
Ulnar nerve muscles
Muscles in hand apart from LLOAF
Radial nerve muscles
Extensor muscles in forearm
Spinal cord lesions specific questions
Preceding trauma
PMH: Osteoporosis
Stroke 5 problems
WAPES
Weakness Aphasia Problems with higher functioning Emotional disturbance Sensory disturbance
Stroke in which lobe causes weakness
Frontal
Stroke in which lobe causes sensory disturbance
Parietal
Stroke in which area causes receptive aphasia
Wernickes, temporal
Stroke in which area causes expressive aphasia
Brocas
Stroke in which area causes disinhibition and impulsivity
Frontal
Stroke in which area causes emotional disturbance
Hippocampus- temporal
Why do you get glove and stocking distribution
Disease of the axon, so the longest axons will be the first to be affected
Whats the difference between distal axonopathies and GBS
GBS has weakness as the main symptom
What causes a distal axonopathy
Response of neurones to metabolic or toxic disturbances
Distal axonopathy questions
Gradual?
Diabetes?
Alcohol abuse, kidney failure?
Vit deficiency? B1 and B12
Malabsorption symptoms
Diarrhoea, foul smelling stools that are hard to flush, weight loss
Which vitamins cause distal axonopathies
B1 and B12
Signs of GBS
Symmetrical, ascending weakness and numbness over weeks
What should you ask about in GBS
Preceding infection?
Respiratory involvement?
What is a red flag in GBS
Respiratory involvement
Which infective agent can cause GBS
EBV
Collapse questions
When did it happen? What were they doing at the time? How many times has this occurred? LOC?
Precollapse symptoms questions
Aura?
Light headed?
During collapse symptoms questions
Tongue biting
Foaming
Incontinence
Post collapse symptoms questions
Rapid recovery
Fatigue
Generalised seizures precipitating events
Usually none, can occur during sleep
Syncope precipitating events
Stress, exercise, excitment
Generalised seizures signs preceding the episodes
Signs related to the prodrome and aura phases
Syncope signs preceding the episodes
Usually none. Sometimes ataxia, vocalisation, urination or defecation
Generalised seizures: during
Motor activity such as tonic clonic, jaw and facial movements. Urination or defecation, drooling. LOC
Syncope: during
Usually flacid collapse. LOC, urination etc more rare
Duration of generalised seizures
Longer than a minute
Duration of syncope
Usually shorter than a minute
After the event: generalized seziures
Signs related to post ictal phase, slow recovery
Signs following the event: Syncope
Rapid recovery
What does NEAD have that epilepsy doesnt
More than 2mins Gradual onset Closed eyes Side to side head moves Tip of tongue biting Fluctuating course May talk during seizure
Differentials of tremor
Parkinsons Benign essential tremor drug induced tremor Alcohol withdrawal Hypoglycaemia Thyrotoxicosis
Tremor HPC questions
Resting or action SOCRATES Gait change? Balance and coordination? Gradual onset=disease
Tremor DHx
Antipsychotics
Tremor SHx
Amphetamines
Tremor FHx
Essential tremor
Three parkinsons signs on examination
Resting tremor
Rigidity
Bradykinesia
Assymetrical onset
Neurological parkinsons symptoms
Anosmia Postural instability Reduced dexterity Micrographia Decreased arm swing Blank face Dysphagia Neuropathy
Autonomic parkinsons symptoms
Constipation Sexual dysfunction Sweating Incontinence Drooling Dizziness
Psychiatric parkinsons symtoms
Depression Insomnia Amnesia Emotional volatility Poverty of thought Visual hallucinations
Parkinsons diagnosis
Clinical
SPECT scanning
Good things to ask in endocrine histories
Fatigue/tiredness Weakness Weight loss Weight gain Hirsuitism
Fatigue, tiredness, neck lump questions
Infection Night seats Neck lump not in midline -anaemia, DM, lymphoma, infective AI PMH
Neck lump differentials
Thyroid swellings
Reactive neck lymphadenopathy
Malignant neck node
Examples of thyroid swellings
Multinodular goitre, solitary thyroid nodule
Examples of reactive neck lymphadenopathy
Tonsilitis
Glandular fever
HIV
Examples of malignant neck nodes
Carinoma metastases, lymphoma
Key hypothyroidism symptoms
Weight gain
Poor memory
Intolerance to cold
Feeling of tiredness
Symptoms of hypothyroidism
Hair thin and loss Puffy face Enlarged thyroid Dry and coarse skin Slow heart beat Constipation Heavy menstruation Poor appeitite Carpal tunnel
Signs of hypothyroidism
Oedema Vocal hoarseness Goitre Delayed relaxation of reflexes Paraesthesia
Key hyperthyroidisim symptoms
Irritability Hyperactivity High blood sugar Intolerance to heat Low cholesterol
Breathless, dysphagia, neck pressure suggests
Large toxic multinodular goitre
Symptoms of hyperthryoidism
Fine brittle hair Bulging eyes Increased sweating Enlarged thyroid Enlarged liver Arrythmias Increased appetite N, V and D Hand tremors Loss of libido Amenorrhea
Hyperthyroidism signs
Agitation, fine tremor, erythema Tachycardia, AF, heart failure, oedema Eye signs Goitre Fine tremor Alopecia Urticaria, pruritus Brisk reflexes Proximal myopathy
What does a tender irregular thyroid gland suggest
Subacute thyroiditis
What is graves disease signs
Lid retraction Exopthalmos Opthalmoplegia Lid lag Pretibial myxoedema
What is exopthalmos
Protrusion of the eye ball, specific to graves
What is opthalmoplegia
Paralysis of the extra ocular muscles which cause diplopia
Risk factors for thyroid eye disease
Smoking
Female
Describe T1 DM
Autoimmune destruction of beta islet cells
Describe T2 DM
Combination of insulin resistance and then islet cell destruction
Acute triad of T1DM
Polyuria
Polydipsia
Weight loss
(tiredness)
Acute triad of T2DM
Polyuria
Polydipsia
Obesity
(tiredness)
Diabetes HPC
Vision problems
Numbness/ tingling
Sexual dysfunction
Skin infections
Diabetes PMH
Stroke
Heart disease
PVD
Kidney problems
T2DM DH
Steroids
T2DM SH
Smoking
Alcohol
Exercise
Diet
T2DM FH
T2DM
T1DM Treatment
Insulin and education
Chronic disease management
T2DM Treatment
1) Lifestyle advice, statin, Ramipril
2) Metformin
Chronic disease management
Cardiac PMH
Hospital/ A&E visits, GP visits
Previous stents
Cardiac FH
M1 <55years 1st degree relative
Cardiac SH
Smoking Alcohol Diet and lifestyle Occupation Home- carers? ADLs?
Respiratory FH
Cystic fibrosis
Asthma, eczema, hayfever
Respiratory PMH
ACE-I
Inhalers
Immunisations
Respiratory SH
Foreign travel Pets Occupation Living conditions Hobbies Long haul flights
Respiratory PMH
Asthma TB PE Allergies Pneumonia Home oxygen Inhalers
CV common presenting complaints
Chest pain Palpitations Ankle swelling Leg pain SOB Syncope and presyncope
Respiratory common HPCs
Cough SOB Asthma COPD Pulmonary fibrosis
Cardiac causes of chest pain
ACS
Pericarditis
Aortic stenosis
Aortic dissection
Aortic stenosis triad
Chest pain
Syncope
Heart failure
Respiratory causes of chest pain
Pulmonary embolism
Pneumonia
Pneumothorax
GI causes of chest pain
GORD
Peptic ulcer disease
Other causes of chest pain
Costochondritis
Rib injuries
Cardiac pain which goes to the trapezius and shoulders
Pericarditis
Cardiac chest pain associated symptoms
SOB, N&V, sweating, palpitations, ankle swelling, syncope, calf swelling, haemoptysis, sputum or trauma
Palpitations questions
TAP OUT BEAT how often, for how long Associations Sweating or SOB Syncope, Chest pain? Associated with exercise? Family history of CVD?
Palpitations red flags
Chest pain
Palpitations associated with exercise
Cardiac causes of palpitations
Cardiac arrhythmias
Valve pathology
Heart failure
Congenital heart disease
Non cardiac causes of palpitations
Psychosomatic, hyperthyroid, anaemia, medication, recreational drugs, caffeine
Left ventricular failure symptoms
Exertional SOB PND Orthopnoea Cough Pink frothy sputum
Right ventricular failure symptoms
Ankle and sacral oedema Cough Ascites JVP Bibasal crackles
What does pink frothy sputum suggest
Left ventricular heart failure
What are the three cardinal signs of heart failure
Exertional SOB, ankle swelling and fatigue
Heart failure questions
How many pillows Sleeping in chair Can they climb stairs Exercise tolerance What was normal for them before
Leg pain symptoms
Leg swelling
Increase in skin temperature
Change in skin colour
Leg pain risk assessment questions
Recent surgery Long haul flight History of malignancy Immobility Previous VTE Family history of VTE
Intermittent claudication questions
How far can walk before pain CVS risk factors Associated symptoms -gangrene, burning, foot pain (hanging foot off bed=critical ischaemia) -impotence
How do you measure intermittent claudication
ABPI
Chronic causes of SOB
COPD
Pulmonary fibrosis
Heart failure
Acute causes of SOB
PE
Asthma attack
Pneumonia
Pneumonothorax
Acute/chronic causes of SOB
Carcinoma of the lung
Pleural effusion
TB
SOB HPC
When
How long does it last
Associated features
What makes it better or worse
Associated features of SOB
Chest pain, palpitations, orthopnoea/PNS, nausea or vomiting, cough, oedema, pain
SOB PMH
Asthma, COPD, VTE
RF for heart disease
SOB DH
Inhalers, drugs, allergies
SOB SH
Smoking
Occupation
SOB FH
Asthma
Cardiac disease
SOB Important extras
SWAFF
Risk factors for VTE
Syncope causes
Vasovagal syncope, postural hypotension, aortic stenosis, cardiac arrhythmias
Syncope questions
Onset, duration Situation Previous episodes How frequently Associated symptoms
Syncope associated symptoms
Palpitations, sweating, chest pain, headache
Things to look out for in CVS examinations
Pacemakers Murmurs AF GTN spray CABG scars on legs
Things to look out for in resp examinations
Sputum pots, oxygen tanks and inhalers
Tar staining on fingers
Walking stick
Prehospital treatment of MI
Morphine
Oxygen
gtN
Aspirin
Kidney transplant signs
Lump and scar
LOC before questions
What were you doing
How did you feel
LOC during questions
LOC Duration Injuries Bite your tongue Incontinent
LOC after questions
How did you feel
Confused
How long was recovery
Epilepsy before
Flashing lights aura
Metallic taste
Altered behaviour
Can be in sleep
Epilepsy during
2-3mins LOC
Stiffness then shaking
Incontinence
Bite side of tongue
Symmetrical
Epilepsy after
Confusion
Tiredness for days
Sycope before
Standing, stress, emotion, eating, coughing, turning head
Palpitations and nausea
Syncope during
Flaccid collapse Multifocal shaking- assymetrical Scream out Random limb movements Less than one minute
Syncope after
Rapid recovery
No marked confusion
Non epileptic attack disorder ebfore
Emotions
Traumatic experiences
Bodily sensations
NEAD during
Fluctuating course eyes tightly shut talking Moving head side to side Longer than 5 minutes
Headaches red flags
Thunderclap headache Altered mental state Focal neurological signs Meningisms Worse on lying down
Tension headaches symptoms
Tight band pain across whole head
Associated with stress
Analgesia induced
Tension headache questions
Do you feel stressed?
Are you taking pain relief?
How much?
Migraine symptoms
Severe throbbing pain on one side of the head.
Photo and phonophobia
Aura
Associated numbness and tingling
Migraine questions
Do you see anything before it happens
Cluster symptoms
Severe ocular pain
Autonomic features
Multiple a day for weeks, years apart with no warning (clusters)
Cluster questions
Has it happened before
Subdural haemorrhage risk factors
Elderly
Epileptic
Alcoholic
recent head trauma
Extradural haemorrhage symptoms
Head injury
LOC
Period of regaining consciousness
V, dizziness, confusion, headaches, LOC
Secondary headaches
EDH SDH SAH Meningitis Encephalitis Raised ICP Temporal arteritis
Subarrachnoid haemorrhage symptoms
Thunderclap headaches- spontaneous, peaks within 5s
Sentinel headaches
SAH PMH
PKD
Ehlers danlos
SAH Ix
CT head, don’t LP
SAH Tx
Surgical coiling/clipping
Meningitis symptoms
Fever Stiff neck Altered conscious state Headache Non blanching purpuric rash Photophobia Vomiting
How do encephalitis symptoms differ from meningitis
Confusion and altered mental state are more prominent
3 things which increase ICP
Brain tumour
Brain abscess
Intracranial bleed
Question for
a) tumour
b) abscess
c) bleed
Weight loss
Fever
Trauma
Temporal arteritis symptoms
Headache, hurts when I eat or brush hair
Painless loss of vision
Temporal arteritis treatment
High dose prednisolone
Temporal arteritis investigations
Temporal artery biopsy
Visual disturbances questions
Do you wear glasses? One eye or both Describe it Triggers or trauma Pain
Amaurosis Fugax desribe
TIA
Curtain coming down over vision
TIA PMHx
HTN
Stroke
AF
DM
Retinal detachment questions
Always painless Many floaters Flashes of light Blurred vision Then curtain like loss of vision
Myasthenia gravis questions
Symptoms worse with use Double vision Ptosis Myasthenic snarl Swallowing problems
Symptoms arising from the thyroid swelling
Duration and change in size Cosmetic symptoms Odynophagia, dysphagia Dyspnoea Hoarseness
Thyroid PMH
Eye symptoms
Previous thyroid operations
Drug history
Radio-iodine therapy for Graves
Breast lump history
SOCRATES Pain Nipple changes Discharge Skin changes Before? Radiation or surgery
Breast cancer risk factors
Early menarche Late menopause 1st pregnnacy >30yo Nulliparty HRT FHx
What to look for for breast cancer
Lump in armpit Lump in breast Dimpled, depressed skin Swelling Nipple changes Breast pain Skin irritation Bloody discharge
Smooth breast lump that moves under skin
Fibroadenoma
Breast lumpiness, thickening and swelling associated with periods
Fibrocystic changes
Red tender breast swelling associated with fever
Mastitis
Breast bruise with lump
Breast trauma
Neuro red flags
LOC, dizziness, headache, visual or speech disturbance, swallowing, sensory changes, bowel and bladder incontinence, meningism, weakness, hearing changes, tremors, N/V, weight loss
Stroke PMH
Arrythmias, MI, HTN, angina, high cholesterol, diabetes
Leg motor gone, which artery was affected
Anterior cerebral artery
Arms, face motor gone. Which artery was affected
middle cerebral artery
Which artery is blocked in amaurosis fugax
Opthalmic artery
Two causes of face paralysis
Stroke or Bells palsy
How can you tell between stroke and bells palsy
Forehead spared in stroke
Face paralysis questions
Drooling difficulty speaking Dry eyes hypersensitive to sound decrease in taste Recent illness?
Treatment for bells palsy
Prednisolone within 72hours
Change classic to MG
Fatigueability
Change classic to MS
Sensory or sphincter loss
Change classic to MND
Upper and lower motor neurone changes
Are fasciculations a sign of upper or lower MN problem
Lower
Is babinskis reflex a sign of upper or lower MN problem
Upper
What is the first change in MG
Eye signs
Numbness and tingling differential diagnosis
Peripheral neuropathy Stroke Nerve root lesion Spinal cord lesion Cauda equina MS
Radiculopathy describe
Back pain and altered sensation along a dermatome. LMN signs.
Myotome weakness
?What were you doing at the time
What is the most common cause of radiculopathy
Slipped disc
Myelopathy describe
Back pain, sensory loss and pain. UMN signs
What is radiculopathy
Nerve root lesions
What is myelopathy
Spinal cord lesions
Specific questions for myelopathy (spinal cord lesions)
Preceding trauma
Osteoporosis
Red flags
Cauda equina symptoms
Severe lower back pain Sciatica Bladder, bowel dysfunction Saddle anaesthesia Sexual dysfunction Neurological deficit
5 possible stroke problems
Weakness Sensory disturbance Aphasia Higher function Emotional disturbance
Where is the lesion if they get weakness
Frontal
Where is the lesion if they get sensory disturbance
Parietal
Where is the problem if they get receptive aphasia
Wernickes- temporal
Where is the problem if they get expressive aphasia
Brocas
Where is the problem if they have problems with higher function
Frontal
Where is the problem if they have emotional disturbance
Temporal- hippocampus
Signs of capral tunnel syndrome
Thumb weakness
RFs: RA, hypothyroid
Signs of. ulnar nerve compression
Trauma to elbow
Weak muscles of hand
Signs of radial nerve compression
Cannot open fist
Classic first symptom of MS
Optic neuritis
Classic sign of MS
Gets worse with heat (stress and illness)
1st line therapy for MS
A happy stress free life
Diabetes questions
Thirst Toilet Tired Infections Eyesigh Tingling ED
Diabetes family history
Diabetes
Stroke
Cardiovascular disease
Diabetes Drug History
Steroids (= hyperglycaemia)
Diabetes Social history
Alcohol
B12 neuropathy pathophysiology
Weakness due to B12 deficiency leading to subacute degeneration of the cord
Cuses of B12 deficiency
Pernicious anaemia, malabsorption, dietary
B12 Questions
AI (Addisons), UC or Crohns
Vegan
SWAFF
Why does low b12 lead to subacute degeneration of the cord
Patchy losses of myelin
Signs and symptoms of subacute degeneration of the cord
Weakness and tingling that progressively worsens
Visual and mental changes
Spastic paresis
Causes of microcytic anaemia
Iron deficiency
Thalassaemia
Haemoglobinopathies
Causes of normocytic anaemia
Acute blood loss Haemolysis Renal failure Chronic disease Cancer
Causes of macrocytic anaemia
B12 deficiency Folate deficiency Alcohol excess Liver/thyroid disease Methotrexate and trimethoprim
General infection questions
Sexual history
Recreational drugs
Holiday
Bitten
Cushings symptoms
Acne Weight gain Gonadal dysfunction Proximal weakness Mood change
Signs of. cushings
Fat distribution Skin changes Osteoporosis HTN Hyperglycaemia, infection prone
Fat distribution changes in cushings
Central obesity
Moon face
Buffalo neck
Supraclavicular fat distribution
Skin changes in cushings
Skin and muscle atrophy
Bruises
Purples abdominal striae
Mood changes in cushings
Depression, lethargy, irritbaility, psychosis
Gonadal dysfunction in cushings
Irregular menses, hirsuitism, ED, virilsation