OS 202 Compre Flashcards
Kluver-Bucy is caused by bilateral lesions of the amygdala. Which of the following will not result from Kluver-bucy syndrome? A. Excessive aggression B. Lack of fear C. Hypersexuality D. Hyperrorality
A
Klüver–Bucy syndrome is a syndrome resulting from bilateral lesions of the amygdala.Klüver-Bucy syndrome may present with hyperphagia, hypersexuality, hyperorality, and docility. The insular cortex mediates aggressive behavior.
The parahippocampal gyrus and occipito-temporal area is supplied by: A. ACA anterior cerebral artery B. MCA middle cerebral artery C. PCA posterior cerebral artery D. MMA middle meningeal artery
C
. What is an example of commissural fiber A. Corticospinal tract B. Corpus callosum C. Cingulum D. Fronix
B
Commissural fibers connect the two hemispheres of the brain. Examples of these are the corpus callosum, anterior and posterior commissures. The corticospinal tract is a projection fiber (connects brain to the rest of the CNS) along with the internal capsule and corona radiate. The cingulum is a type of association fiber ( connects different parts within the same hemisphere) along with the arcuate fasciculus, unicinate fasciculus, IOF and SOF.
The vagus nerve exits via the: A. Interpeduncular fossa B. Pontomedullary sulcus C. Anterolateral sulcus D. Posterolateral sulcus
D
To be specific, the vagus nerve exits the MEDULLA via Posterolateral sulcus. However, if the question asked where the vagus nerve exits the skull then the answer would be the jugular foramen along with CN X
The cerebrospinal fluid escapes the 4th ventricle via A. Midline Magendie foramen B. Jugular foramen C. A pair of Magendie foramen D. Pacquiao granules
A
There are only 3 apertures for CSF to exit via the 4th ventricle: One foramen of Magendie (midline) and two foramen of Luschka (lateral)
Accounts for Absolute Refractory Period A. open voltage-gated Na channels B. Closure of activation gate of voltage gated Na channels C. Efflux of K via leak channels D. All of the above
B
Absolute refractory period is the state when a cell is unable to fire a second action potential no matter how strongly it is stimulated. The cell is refractory because a large fraction of its Na channels are voltage inactivated and cannot be reopened until membrane potential is repolarized. The critical number of Na channels required to produce an action potential cannot be recruited. (Berne & Levy)
What is the effect of myelin sheaths on action potential transmission? A. Increased conductance B. decreased space constant C. Increased time constant D. all of the above
A
Myelination increases conduction velocity of a nerve axon. An action potential is conducted rapidly and with little decrement from one node of Ranvier to the next.
What is the effect of increased (luminal?) intravascular pressure in the brain vasculature (something like this)
A. Vasoconstriction and reduced blood flow
B. Vasoconstriction and increased blood flow
C. Vasodilation and increased blood flow
D. Vasodilation and reduced blood flow
A
CBF = (MAP – CVP) / CVR
An increase in intravascular pressure transmits this to the venous system, thereby increasing CVP (Central Venous Pressure), decreasing blood flow, and vasoconstricting the vessels.
What is the effect of reduced oxygen pressure (PaO2)
A. Vasodilation and increased cerebral blood flow
B. Vasodilation and decreased cerebral blood flow
C. Vasoconstriction and increased cerebral blood flow
D. Vasoconstriction and decreased cerebral blood flow
B
Decreased PaO2 causes vasodilation and means decreased cerebral blood flow.
The structure that divides the corpus striatum into the caudate nucleus and the lentiform nucleus is the: A. Internal capsule B. External capsule C. Claustrum D. Extreme capsule
A
Balance and vestibulo-ocular reflexes are associated with functional zone of the cerebellum A. Vermis B. Intermediate C. Lateral Hemisphere D. Flocculonodular Lobe
D
Connects conus medullaris to coccyx
A. Cauda equina
B. Filium terminale
B
. The conus medullaris is found at this level: A. S2-S4 B. L1-L4 C. S1-S3 D. L2-L4
A
How many pairs of spinal nerves are there? A. 30 B. 31 C. 32 D. 33
B
What is the structure which separates the frontal bone from the parietal bone?
A. Sagittal suture
B. Coronal suture
B
What is the smallest functional unit of a muscle? A. Myofibril B. sarcolemma C. Sarcomere D. Neuron
C
Which of the following post synaptic potentials in millivolts is near the firing rate? A. 3, -10, +7, -2 B. 7, 10, -2, -3 C. -20, 5, 7, -2 D. -12, 4, 7, -8
B
The structural division of the Cerebellum
A. The anterior commissure divides the anterior from the posterior lobe
B. The paramedian zone of the cerebellum is between the vermis and the lateral zone
C. The posterolateral fissure divides the posterior lobe from the flocculonodular lobe
D. AOTA
B
The phrenic nerve is comprised of which of the following cervical roots? A. C1-C3 B. C3-C5 C. C1-C5 D. C2-C4 E.C2-C5
B
What neurotransmitter is produced by the substantia nigra? A. Norepinephrine B. Epinephrine C. Dopamine D. Acetylcholine E. Glutamine
C
Which neurotransmitter is found in the corticostriate pathway? A. glutamate B. dopamine C. norepinephrine D. acetylcholine
A
What is responsible for myelination in the CNS? A. Ependymal cells B. Astrocyte C. Oligodendrocyte D. Schwann Cell E. Microglial cells
C
What is responsible for pruning of the synapse? A. Microglia B. Astrocytes C. Ependymal cells D. Oligodendrocytes
A
Structure most likely to be damaged by rapid enlargement of lateral ventircles: A. Fornix B. Corona radiata C. Posterior commissure D. Anterior commissure
B
The obex is found in the: A. Tectum B. Facial fasciculus C. Superior colliculus D. Rostral medulla
D
This tissue serves as origin of DRG, autonomic ganglia, Schwann cells and plexuses A. Alar plate B. Sulcus limitans C. Neural crest D. Basal plate
C
Color recognition and identification in the visual pathway: A. cones B. optic chiasm C. superior colliculus D. secondary visual pathway
A
Cones are for color while Rods are for black and white (contrast)
Lesion of the right CN XII or of the supranuclear corticobulbar fibers on the right side will be manifested by this finding in tongue protrusion:
A. Remains midline
B. Deviates to right upon tongue protrusion
C. Deviates to left upon tongue protrusion
D. Poor gag reflex
B
.Alexia without agraphia. Where is the lesion?
Alexia – cannot read, Agraphia – cannot write
Lesion is in the ANGULAR GYRUS. This is found at the junction of association areas for vision, hearing, balance, touch, and position sens. The association area for all association areas. It connects different modalities with Wernickes! Other lesions in the angular gyrus: Alexia with agraphia, pure word blindness, out of body experiences
The aphasia where a patient can speak fluently and understand what you say but cannot repeat what you ask her to repeat is A. Wernicke’s aphasia B. Broca’s aphasia C. Conduction aphasia D. Global aphasia
C
Conduction aphasia: fluency and understanding is good but poor repetition and naming. Wernicke’s aphasia: good fluency but poor understanding, naming and repetition. Broca’s aphasia: poor fluency but good understanding, poor repetition and naming. Broca’s area is for speech production, Wernicke’s for associating speech sounds with meaning
Asking what the patient would do if they get somebody else’s mail is an example of a test for the patient’s... A. Intelligence B. Abstract reasoning C. Judgment D. Insight
C
A test where the examiner flicks the distal interphalangeal joint of the third finger upward
A. Hoffman B. Tromner C. NOTA
B
Tromner equals T. T for top/ Going up!
In the examination of the meninges
A. To test for Kernig’s sign, examiner holds the patient’s occiput and passively flexes the neck until the chin touches the neck
B. To test for Brudzinski’s sign, examiner asks the patient to lie supine and flexes the patient’s hip and knee to 90 degrees
C. A and B are correct
D. A and B are incorrect
D
They switched the definitions for both signs.
Damage to which of the anatomical structures leads to a lower motor neuron paralysis?
A. Neuron of the primary motor center
B. Axons of the internal capsule
C. Decussating axons of the medullary pyramid
D. Corticospinal tract
E. Cells of the anterior horn of the spine
E
Lower motor neuron begins from the cells of the anterior horn up to the respective peripheral nerve for the myotome.
This indirect pathway reaches as far as the cervical spinal cord, where it innervates predominantly alpha motor neurons that innervate flexors of the upper limb A. Tectospinal pathway B. Vestibulospinal pathway C. Pontine Reticulospinal pathway D. Medullary Reticulospinal pathway E. Rubrospinal pathway
E
Rubrospinal for flexors of arms and hands. Tectospinal: coordinate head and eye movements ; Vestibulospinal: reflex control of posture and balance ; Pontine reticulospinal: extensors, inhibit flexors ; Medullary reticulospinal: inhibitory to segmental reflexes
Edinger Westphal nucleus is for
A. blinking
B. lateral gaze
C. pupil constriction
C
Edinger Westphal Nucleus is an accessory parasympathetic CN III nucleus for pupil constriction and accommodation.
An 80-year-old male comes to you for a general check-up. Upon doing the neurologic exam, you note that there is decreased reflex at the \_\_\_\_\_\_\_\_\_\_\_\_(knee?). A. Jaw reflex B. Brachioradialis reflex C. Triceps reflex D. Patellar reflex
D
Congenital anomaly of dorsal induction? A. Holoprosencephaly B. Anencephaly C. Cleft palate D. Macrocephaly E. Microcephaly
B
The particular muscle to zero in to discriminate UMN/LMN lesion. A. Frontalis B. Nasalis C. Buccinator D. Orbicular Oris
A
Frontalis since this has bilateral innervations while lower half is contralaterally innervated.
The following are effects of oxytocin except:
A. Maternal behavior
B. Contraction of myoepithelium of the breast
C. Inhibition of prolactin release
D. Contraction of myometrium of uterus
C
From corticosterone A. cortisol B. aldosterone C. both D. neither
C
Which of the following cells produce insulin? A. alpha cells B. beta cells C. D cells D. F cells
B
Which of the glucose transporters is present in skeletal and cardiac muscle, and adipose tissue and facilitates insulin-mediated glucose uptake? A. GLUT 1 B. GLUT 2 C. GLUT 3 D. GLUT 4
D
The most important glucose transporters are Glut 1, 2, and 4. Glut 1 is insulin-independent and is responsible for protecting the CNS from glucose deprivation. Glut 2 acts as a beta cell glucose sensor. Finally, Glut 4 is insulin-dependent, and is found in insulin-sensitive organs, such as skeletal muscle, cardiac muscle, and adipose tissue. Thus, D is the answer.
The parathyroid hormone primarily mediates the following physiological effect:
A. Increased bone resorption
B. Increased renal tubular reabsorption of calcium
C. Increased intestinal absorption of calcium
D. Acid-base balance
A
Which of the following are thyroid hormone transport proteins? A. Thyretin B. Thyroid binding globulin C. Albumin D. All of the above
D
The following statements regarding the Resting Membrane Potential (RMP) being in a “steady state” are true EXCEPT:
A. No net flow of ions
B. Constant transmembrane potential
C. RMP in equilibrium
D. The sum of all ionic currents flowing across the membrane must equal zero.
C
The following decreases Cerebral Blood Flow EXCEPT:
a. Anemia
b. Atherosclerosis
c. Osteoporosis
d. Increased intercranial pressure
A
. Abnormalities in what stages of the brain development result in Neurocutaneous Syndrome? A. Neuronal migration B. Neuronal proliferation C. Dorsal induction D. Myelination
B
Compression of what nerve causes Carpal Tunnel Syndrome?
A. Radial Nerve
B. Ulnar Nerve
C. Median Nerve
D. Musculocutaneous Nerve
C
Which nerve innervates the brachialis and biceps brachii?
A. Radial nerve
B. Common peroneal nerve
C. Obturator nerve
D. Musculocutaneous nerve
D
What passes from midbrain to cervical cord? a. mesencephalic nucleus of CN V b. principal nucleus of CN V C. Spinal Nucleus of CN V d. spinal accessory
C
Which of the following is responsible for the blood supply of the anterior ⅔ of the spinal cord from T8 to conus medullaris? A. Artery of Adamkiewicz B. Posterior spinal artery C. Vertebral artery D. Innominate artery
A
What is the dural reflection that separates the cerebrum from the cerebellum? A. Tentorium Cerebelli B. Falx Cerebri C. Falx Cerebelli D. Diaphragma Sella
A
These cells stain with Glial fibrillary acidic protein (GFAP) A. Astrocytes B. Oligdendrocytes C. Microglia D. Ependymal Cells
A
The outer band of Baillarger or line of Gennari corresponds to which layer? A. External Granular B. External Pyramidal C. Internal Granular D. Internal Pyramidal
C
Which of the following bind to intracellular receptors?
a. T3 and TSH
b. ACTH and cortisol
c. testosterone and estrogen
d. insulin and glucagon
C
Peptide and proteins
a. are produced initially as inactive prehormone
b. require binding with plasma protein
c. bind to nuclear receptors
d. derived from cholesterol
A
Which of the following is true about insulin?
a. The active hormone is composed of 4 peptides
b. The secretory granules contain insulin and c-peptide in 2:1 ratio
c. insulin is released into the duct of Wirsung to reach the liver
d. The order of synthesis of the polypeptide chain is n-terminal signal peptide- b-chain- c-peptide- insulin
D
Transection of pituitary stalk
a. Decreased cortisol, decreased ACTH
b. Increased cortisol, decreased ACTH
c. Decreased cortisol, increased ACTH
d. Increased cortisol, increased ACTH
A
Tuberculous infiltration of adrenal cortex
a. Decreased cortisol, decreased ACTH
b. Increased cortisol, decreased ACTH
c. Decreased cortisol, increased ACTH
d. Increased cortisol, increased ACTH
C
ACTH producing pituitary adenoma
a. Decreased cortisol, decreased ACTH
b. Increased cortisol, decreased ACTH
c. Decreased cortisol, increased ACTH
d. Increased cortisol, increased ACTH
D
ACTH secreting tumor
a. Decreased cortisol, decreased ACTH
b. Increased cortisol, decreased ACTH
c. Decreased cortisol, increased ACTH
d. Increased cortisol, increased ACTH
D
Insulin affects the metabolism of which substances?
a. carbohydrates
b. carbohydrates and fats
c. carbohydrates and proteins
d. carbohydrates, fats and proteins
D
With inactivating mutation to GLUT-2 transporter
a. patient loses consciousness and seizure
b. pancreas do not produce insulin when glucose increases after meals
c. glucose is not transported to muscles and adipose
d. fructose is not transported to sperm
B
What happens after pancreatectomy?
a. hypoglycemia
b. decreased FFA
c. decreased acetoacetate
d. metabolic alkalosis
D
Which of the ff is not a direct effect of PTH?
a. increased bone resorption
b. increased intestinal absorption of calcium
c. increased renal tubular reabsorption of calcium
d. decreased renal tubular absorption of phosphate
B
Your grandmother wants to prevent osteoporosis by taking calcium tablets. However, she takes 20 pcs of 500 mg tablets daily, way more than recommended. What are the physiologic adaptations that occur as a response?
a. PTH gland secrete more PTH
b. 1-α- hydroxylase enzyme activates Vit D
c. Renal tubular absorption of Ca is inhibited
d. Increased osteoclastic activity
C
Basophilic cells of adenohypophysis
a. lactotroph
b. somatotroph
c. thyrotroph
d. corticotroph
A
Salt Loading
a. Decreased renin, decreased aldosterone
b. Increased renin, decreased aldosterone
c. Decreased renin, increased aldosterone
d. Increased renin, increased aldosterone
A
Which is true about insulin secretion?
a. Decreased glucose, decreased insulin secretion
b. Increased glucose, decreased insulin secretion
c. Decreased glucose, increased insulin secretion
d. Increased glucose, increased insulin secretion
D