Orthopaedic Problems of the Hand Flashcards
What is the M:F incidence of Dupuytren’s disease in 15-64s?
M:F
8:1
What is the M:F incidence of Dupuytren’s disease in over 75s?
M:F
2:1
What are the genetic features of Dupuytren’s disease?
Disease develops earlier in males
Autosomal dominant with variable penetrance
Sporadic in 30% of cases
Onset may be sex-linked
What races are affected by Dupuytren’s disease?
Almost exclusively white races
What are some of the conditions/causes linked to Dupuytren’s disease?
Diabetes mellitus Excess alcohol Tobacco smoking HIV Epilepsy
What is the presentation of Dupuytren’s diathesis?
Early onset disease
Bilateral disease
Family history
Ectopic disease
What is Dupuytren’s diathesis an indication of?
Severity and strong genetic predisposition
What is the pathology of Dupuytren’s diathesis?
Myofibroblast
Thickening and contracture of palmar fascia
Intracellular contractile element, regulated by growth factors, produces collagen
What are the symptoms and signs of Dupuytren’s contracture?
Usually not painful
Loss of finger extension - active or passive
May see skin pits
MCP/PIP joint contracture
Table-top test - can they get their hand flat on the table, if not, this may be indicative of necessary treatment
Most commonly affects little and ring fingers
Radial disease means they are more likely to have rapid recurrence
What is the non-operative treatment of Dupuytren’s?
Observe
Splints don’t work
Radiotherapy (less common in UK)
What is the operative treatment of Dupuytren’s?
Mainstay of treatment in the UK
Partial fasciectomy - remove thickened fascia
Dermo-fasciectomy - remove fascia and skin then replace with skin graft, most extensive operation but least recurrence
Arthrodesis
Amputation
Percutaneous needle fasciotomy
Collagenase
NB - Dupuytren’s can be treated but not cured
What are the features of a partial fasciectomy?
Most common procedure in the UK Good correction can be achieved Wounds take 2-3 weeks to heal Stiffness requires physiotherapy Recurrence 50% at 5 years
What are the features of dermo-fasciectomy?
More radical, generally done for recurrence
Removal of skin may reduce the recurrence rate
Requires intensive physiotherapy
What are the features of percutaneous needle fasciotomy?
Quick No wounds Return to normal activities in 2-3 days Does not prevent traditional surgery in the future Higher recurrence - 50% at 3 years Can be repeated Risk of nerve injury
What are the features of collagenase treatment?
Presented 3 year recurrence rate 34.8%
3 flexor tendon ruptures/300 patients in trials
Expensive
Longer-term recurrence rates currently unknown