Ortho/Rheum Flashcards

1
Q

what presents as widespread muscular pain, fatigue, muscle tenderness, headaches, poor sleep and memory problems

A

fibromyalgia

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2
Q

how is fibromyalgia diagnosed

A

process of elimination

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3
Q

what is the treatment of fibromyalgia

A

stress reduction
sleep/exercise
antidepressants and anticonvusants

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4
Q

what are FDA approved medications for the treatment of Fibromyalgia

A

Duloxetine (cymbalta)
Milnacipran (Savella)
Pregabalin (Lyrica)

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5
Q

what causes gout

A

altered purine metabolism and sodium urate crystal precipitation into the synovial fluid

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6
Q

what is podagra

A

Gout of MTP

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7
Q

how is gout diagnosed

A

arthrocentesis
- rod-shaped negatively birefringent
- serum uric acid levels >8

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8
Q

what is the medication of choice for gout treatment

A

indomethacin
colchicine

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9
Q

what is pseudogout

A

usually >60yo, large joints, LE, No tophi

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10
Q

how is pseudo gout diagnosed

A

rhomboid-shaped calcium pyrophosphate
positively birefringent

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11
Q

what is the treatment of pseudogout

A

NSAIDs, colchicine, intra-articular steroid injection

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12
Q

what is used for prophylaxis of pseudogout

A

colchicine

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13
Q

what is the treatment for acute attacks of pseudogout

A

NSAIDs

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14
Q

what is the T score for osteoporosis

A

< -2.5

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15
Q

what is the t score for osteopenia

A

(-1 to -2.4)

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16
Q

what AE is associated with bisphosphonates

A

osteonecrosis of the jaw

17
Q

what is another name for Reiter Syndrome

A

reactive arthritis

18
Q

what is reactive arthritis

A

autoimmune response to infection in another part of the body (chlamydia +/- gonorrhea MC)

19
Q

what is the presentation of reactive arthritis

A

asymmetric inflammatory arthritis
Conjunctivitis, uveitis, urethritis, and arthritis (cant see, cant pee, cant climb a tree)

20
Q

what are the treatment options for reactive arthritis

A

NSAIDS = mainstay
abx to treat infection that triggered disease

21
Q

what presents wtih morning joint stiffness that improves later in the day

A

Rheumatoid arthritis

22
Q

what are diagnostic studies for rheumatoid arthritis

A

(+) Rheumatoid arthritis
(+) Anti-cirullinated Peptide antibodies

23
Q

what is the treatment for rheumatoid arthritis

A

DMARDS
- methotrexate
- hydroxychloroquine
- sulfasalazine
- leflunomide

24
Q

what presents with the triad of joint pain + fever + malar rash

A

systemic lupus erythematosus (SLE)

25
Q

what diagnostics tests are positive with SLE

A

(+) ANA and (+) anti-double-stranded DNA and Anti-Smith Ab

26
Q

what is the treatment of SLE

A

manage with sun protection, hydroxychloroquine (for skin lesions), NSAIDs or tylenol for arthritus