origins Flashcards
paranasal sinuses
ectoderm
pharynx
ectoderm
sebaceous gland
ectoderm, holocrine
eccrinen gland
ectoderm
salivary gland
ectoderm, merocrine and multiglandular
mammary glannd
ectoderm, apocrine
posterior pituitary gland
ectoderm, neural tube
- oxytocin and ADH to kidney NOT MADE HERE
pineal gland
ectoderm
epithelium of blood + lymph vessles
mesoderm
andrenal cortex origin
mesoderm
cytokeratins
made by all epithelium cells
-intermediate filament
grocott methenamine silver
stains type iii collagen, fungus and microbes black
siehl neelsen acid fast bacilli stain
stains microbes purple
silver stain
stains reticulin black
wrights stains
stains rBC pink
connective tissue
mesoderm
connective tissue function
SEDS
- structure
exchange
defense
storage of fat
macrophage in liver
kuppfer cells
macrophage in skin
langerhans
somatic system
impulses directly transmitted to skeletal muscle via 1 neuron
autonomic
PNS
- impulse transmitted to autonomic ganglia then second neuron to the muscles
- fight or flight
endocrine gland
endocrine
liver
ENDODERM
pancreas
endoderm
respiratory tract
endoderm
kidney
mesoderm
gonads
mesoderm
endothelium
mesoderm
what is mesothelium
epithelium of various body cavities:
- thoracic (pleura)
- abdominal (peritoneum)
- pericardium (heart sac)
- male internal organs
cytokeratins
- produced by all epithelial cells in the cytoplasm (serves as a marker)
- intermediate filament proteins
- give cells their architecture
all cells have
1 cillis
multicell exocrine gland
- all cells produce the secretion together
- simple: intestinal
- compound: salivary
kidney functions
A - acid base balance
W - water removal
E - erythropoeisis
T - toxin removal
B - blood pressure control
E - electrolyte balance
D - vit D activation
kidney capsule
- outer layer is fibroblast
- inner is myofibroblast
- dense irregular connective
renal medulla and calyx
- 6-12 renal pyramids
- apex of each is minor calyx
- major = 2-3 minor
- renal pelvis joins the ccalyces
what is in a nephron
- renal corpuscle
- proximal connvluted tubule
- loop of henle
- distal ct
where is macula densa found and how does it work
- btw ascending loop and dct
- sense low concentration of na, trigger jga cells to release renin etc and shut off naturetic peptides
what does aldosterone do
- acts on connecting tubules and collecting ducts
- increases na and water
- k secretion
- increases bp and volume
natriuresis peptides
- vasodilation
- inhibit reninn release
- decrease bp
- more sodium and water out
what is in kidney cortex
- renal corpuscle
- tubular network
- medullary rays
- a bit of loop and collecting duct too
tubular network
- convoluted and straight tubes of nephron
- connecting tubules
- collecting ducts
- rich vasculature
medullary rays
- straight and collecting ducts
- for water??
whats in kidney medulla
- straight tubes, collecting duct, vasa recta, medullary pyramid with cortical column
- bulk of loop of henle
pee path
- collecting duct, minor calyx, major, renal pelvis, ureter, urinary bladder, urethra
- three openings
where is transitional epi found
- urinary bladder
- calyces
- ureters
- urethra initial segment
what is in lamina propria
- part of mucosa
eosinophile - lymph tissue called galt
what glands secrete into mucosa
- mucosal, submucosal, extramural (from liver and pancreas)
tissue layers respiratory of esophagus tract
in to out:
- lamina propria
- muscularis mucosa
- submucosa
- muscularis externa
- serosa
- adventita
where to find adventitia mucus
- thoracic portion of esophagus, duodenum, ascending and descending colon, anal canal
- connective tissue that fixes stuff to wall
parietal cells make
hcl and intrinsic factor (binds b12)
what is in gastric juice
- water, electro, hcl, pepsin, mucus, IF
- submucosa of duodenum
- has brunner glands that secrete basic stuff
b12 absorption
- binds to haptocorrin in salivary and stomach then broken in stomach by IF. then taken to duodenum, rebound by HC and then absorbed by SI
large intestine mucosa
- smooth with no villi and stuff
- no paneth cells in the crypts
- lamina propria has LOTS of GALT with little lymph drainage
vascular endothelium
- simple squamous epi
- makes growth factors and mediators
- modulates blood flow and vascular resistance
- no spontaneous clotting
- regulars immune and innflammatory response
- metabolize L and VLDL
tunica intima
- simple squam endolthelium
- arteries have elastic mem
tunica media and how to stain
- smooth muscle
- elastic fibers
- external elastic mem (not present inn arterioles)
- VVG stain
tunica adventitia
- dense irregular connective tissue
- has vasa vasorum and nervi vasorum for large things
connective tissue skeleton of heart
- tricuspid (ra to rv)
- pulmonary (rv/ pa)
- mitral or biscuspid (la/lv)
- aortic. valve (lv/aorta)
where does coronary artery originate from
ascending aorta
heart calculation
cardiac output = stroke volume x heart rate
thoracic duct and right lymphatic duct
- left side with 3/4 fluid
- drained by subclavian vein
- right drained by right lymph duct
*both empty into junction of internal jugular and subclavian veins, then inferior vena cava, then heart
where to find b cells in lymph node
- in geminal centers using CD20 immunohistochem
- t cells are found outside of that
what is in upper tract respiratory
- nasal cavities, paranasal sinus, nasopharynx, oropharnyx
lower tract respiratory
- larynx, trachea, bronchi, lungs (from foregut endoderm)
where does cartiledge end and what is the cell type
- in bronchioles
- also lined by ciliated cuboidal epi
where do ciliated cells end
- alveolar duct (a bit sooner)
order of air
tertiary bronchus, bronchiole, terminal bronchiole, respiratory bronciole, alveolar duct, alveolar sac, alveoli
where is pulmonary lobule
terminal bronchiole, respiratory bronciole, alveolar duct, alveolar sac, alveoli
where is pulmonary acinus
respiratory bronciole, alveolar duct, alveolar sac, alveoli
**has its own blood supply!
where to find surfactant secreting cells + cell type
bronchioles and alveoli
- clara, club or bronchial exocrine cells, type II alveolar cells
- not cilliated, cuboidal
where to find type I alveolar and macrophages
- in alveoli
- type I is simple squam
- macrophages are dust cells
co2 cycle in lung
goes into blood as co2, binds either HB OR gets converted in HCO3- by carbonic anhydrase using water
- then goes opposide and released as co2 and water in lung
bronchial circulation
- supply all lung BUT not alveoli (they have pulmonary circulation with 4 veins)
- crosses with pulmonary venules
- most of this blood leaves lung via pulmonary vein
- some is sent to superior vena cava so IT MIXES WITH OX BLOOD then to azygos vein
prepuce of genital organ
ectoderm
alimentary tract
endoderm
gi tractk
endoderm
respiratory tract
endoderm
liver
endo
pancreas
endo
where to find simple columnar cells
intestinal linning, ameloblasts
where to find simple cuboidal cells
ducts, kidney tubules, thyroid follicles
which cells originate in bone marrow
NEB, lymphocyte, plasma cell, mast cell
myofibroblasts
can be derived from things other than fibroblasts
mast cells can be stained with and secrete what?
toluidine blue, purple
secrete heparin and histamine
where do macrophages mature
in connective tissue
where to find reticulin
- around adipose and liver sinusoids
whats inside loose connective tissue
fixed cells, collagen, elastin, ground substance, fluid, nerve and blood