organisation of cells Flashcards

week 5

1
Q

what is a cell?

A

smallest part of an organism that retains characteristics of the entire organism
is the place where metabolic processes occur that keep the organism alive

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2
Q

4 examples of tissues
where can they be found?

A

epithelium - skin, lining of GI tract
muscle - skeletal, smooth, cardiac
nervous
connective - tendons, ligaments, fats, blood, bones

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3
Q

what is the simplest form of a cell?

A

prokaryotes
eg. archaea, bacteria

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4
Q

where is DNA in prokaryotic cells?

A

free floating within the cell cytoplasm

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5
Q

where is DNA in eukaryotic cells?

A

bound inside a nucleus

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6
Q

organelles are only present in which type of cell?

A

eukaryotic

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7
Q

3 components of a typical animal cell

A

plasma membrane
cytoplasm
nucleus

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8
Q

function of plasma membrane

A

separates internal conditions from external conditions
contains protein channels, carriers and pumps for selective permeability
contains cell adhesion molecules (CAMs)

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9
Q

what is the role of CAMs?

A

to attach cells to each other

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10
Q

what does selective permeability allow?

A

the maintenance of membrane potential - the charge difference across the plasma membrane

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11
Q

define ion

A

atom/ molecule with a net electric charge due to the loss or gain of electron(s)

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12
Q

2 components of cell cytoplasm:

A

cytosol and organelles

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13
Q

define cytosol

A

the fluid part of the cytoplasm

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14
Q

what does the cytosol contain?
3 examples

A

proteins and dissolved substances
eg. ions
cytoskeleton
cytoplasmic inclusion eg. lipid droplets or pigments (melanin)

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15
Q

3 functions of cytoskeleton

A

support the cell and holds the nucleus and other organelles in place
movement
transport substances

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16
Q

what are the 3 groups of proteins in the cytoskeleton?
example

A

microtubule - for cell structure - made from tubulin and stiffer than actin filaments eg. flagella, cilia
microfilament - highly organised eg. muscle cells (biggest)
intermediate filament (found in motile organisms and cell division) - flexible but resist strain eg. skin cells

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17
Q

function of the nucleus

A

contains all the cell’s chromosomes which encodes genetic material
has nuclear pores to allow RNA, ribosomes and macromolecules to move between the nucleus and cytoplasm

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18
Q

function of mitochondria

A

provides energy for the cell in the form of ATP

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19
Q

5 components of mitochondria

A

smooth outer membrane
intermembranous space
inner membrane folded into cristae
matrix
circular chromosome

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20
Q

define chromatin

A

delicate filaments found in the nucleus that are formed from dispersed chromosomes

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21
Q

what happens to chromatin during cell division?

A

becomes densely coiled forming chromosomes

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22
Q

during transcription, the enzyme … uses DNA as a template to produce a … …

A

RNA polymerase
pre-mRNA transcript

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23
Q

the pre-mRNA is … to form a … mRNA molecule that can be … to build the protein molecule encoded by the original gene

A

processed
mature
translated

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24
Q

the nucleolus forms to …

A

maximise interactions between specific DNAs, RNAs and proteins

25
Q

active cells have a … nucleolus

A

big

26
Q

inactive cells have … nucleolus

A

no

27
Q

function of ribosomes

A

sites of protein synthesis for inside the cell

28
Q

what do ribosomes consist of?

A

ribosomal RNA (rRNA) and proteins
has a large subunit and a small subunit

29
Q

function of ribosomes on the rough endoplasmic reticulum

A

produce the proteins that are packaged and secreted to be incorporated into the plasma membrane and within lysosomes

30
Q

function of rough endoplasmic reticulum

A

modifies proteins for secretion

31
Q

function of smooth endoplasmic reticulum

A

lipid production (eg. membrane phospholipids) and carb metabolism
processes proteins - modifies drugs or stores calcium ions (in muscles)

32
Q

function of golgi apparatus

A

sorts, packages and transports cell products

33
Q

3 important roles of golgi apparatus:

A

modification of macromolecules
proteolysis of peptides into active forms
sorting of different macromolecules into specific membrane-bound vesicles

34
Q

how does the golgi apparatus modify macromolecules?

A

by the addition of sugars to form oligosaccharides

35
Q

what are the 3 functional components of the golgi?

A

cis face
medial golgi
trans-golgi network

36
Q

function of vesicles

A

transport or store material
allow the exchange of cell membrane between different cell compartments

37
Q

what are the main types of vesicles? (5)

A

cell surface-derived endocytotic (pino/ phagocytotic)
golgi-derived transport and secretory vesicles
ER-derived transport vesicles
lysosomes
peroxisomes

38
Q

function of lysosomes

A

transport digestive enzymes
digest microbes, worn out cellular components or cells

39
Q

what are the 3 main types of cell-cell connections?

A

tight junctions
desmosomes
gap junctions

40
Q

how do tight junctions join cells together?
example

A

form a seal that is so strong not even ions can pass across
eg. blood vessels, kidneys

41
Q

how do desmosomes join cells together?
example

A

connect the intermediate filament networks of adjacent cells
eg. skin, intestines

42
Q

how do gap junctions join 2 cells?

A

allow direct cell-cell communication and selective diffusion of molecules
eg. heart cardiac muscle - to contract at the same time

43
Q

intermediate filaments provide … support especially for … … of the cell

A

structural
mechanical resistance

44
Q

are intermediate filaments directly involved in cell movements?

A

no

45
Q

what are intermediate filaments made from?

A

lots of different types of proteins

46
Q

what are actin microfilaments/ microfilaments made from?
what do they form?

A

actin molecules
they form bundles, sheets or networks

47
Q

what are microtubules made from?

A

alpha and beta tubulin

48
Q

what are microtubules responsible for in the cell?

A

mitotic spindle, cilia and flagella

49
Q

4 functions of microtubules

A

mitotic spindle, cilia, flagella
provide structure and support to the cytoplasm
transport intercellular material by providing tracks for organelles and chromosome movement
maintain cell’s polarity - filaments have + and - ends

50
Q

3 examples of microtubules

A

kinesins
myosins
dyneins

51
Q

where do basal bodies occur?

A

in ciliated or flagellated cells

52
Q

what do basal bodies and centrioles have in common?

A

they have the same structure

53
Q

where do centrioles occur?

A

in the centrosome of cell
involved in mitotic division

54
Q

define centrosome

A

organelle made of 2 centrioles

55
Q

define cilia
example of where they are

A

small and numerous projections on cell surfaces that ‘beat’ in a co-ordinated power stroke vs recovery stroke (active movement)
eg. respiratory tract, female reproductive tract

56
Q

define flagella

A

larger singular version of cilia that moves the entire cell
movement is corkscrew

57
Q

where is the energy for sperm motility derived from?

A

metabolism of fructose in seminal fluid

58
Q

where are the mitochondria located in sperm?

A

their midpiece

59
Q

cilia and flagella are … projections that grow from … that have moved to the cell membrane

A

microtubule-based
centrioles