cell metabolism and enzymes Flashcards

week 8

1
Q

define cell metabolism

A

collective chemical reactions performed by cells

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2
Q

define metabolic pathway

A

series of enzyme-controlled reactions
each reaction is specific
overall set of reactions is energetically favourable

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3
Q

what are the 2 main classes of metabolic pathways?

A

catabolic and anabolic

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4
Q

define catabolic metabolism

A

breaking down fuel molecules to generate energy

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5
Q

define anabolic metabolism

A

using energy to build complex biomolecules required for life

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6
Q

when is a reaction thermodynamically favourable?

A

when 🔼G < 0 (negative)

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7
Q

when is a reaction thermodynamically unfavourable?

A

when 🔼G > 0 (positive)

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8
Q

name 3 fuel molecules in animals

A

carbs, fats, amino acids

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9
Q

how is energy released by fuel molecules?

A

by oxidation

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10
Q

more reduced carbon fuels have … stored energy

A

more

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11
Q

define activated carriers
examples

A

biomolecules that store energy in the form of transferable chemical groups
ATP, NADH, Coenzyme A

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12
Q

how does NADH store energy?

A

as transferable electrons

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13
Q

NAD+ can accept … electrons and a … to form …

A

2
proton
NADH

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14
Q

what is Coenzyme A a carrier of?

A

acyl groups

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15
Q

what bonds do acyl groups form to CoA?

A

thioester bonds

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16
Q

where does glycolysis take place?

A

in the cytosol

17
Q

what are the products of glycolysis?

A

pyruvate
4 ATP (net 2 ATP)
NADH

18
Q

how many different enzyme catalysed reactions are in glycolysis?

19
Q

in aerobic respiration what are the electrons passed on to? what does it form?

A

oxygen
forms water

20
Q

in anaerobic respiration what are the electrons passed on to? what does it form?

A

lactate (organic molecule)
forms lactic acid

21
Q

what is the product of alcoholic fermentation?

22
Q

pyruvate is … into ethanol

A

decarboxylated

23
Q

what pathway does acetyl CoA enter?

A

citric acid cycle (Krebs)

24
Q

what are the 2 main components oxidative phosphorylation?

A

electron transport chain and chemiosmosis

25
when are catabolic pathways activated?
when energy supply is low
26
when are anabolic pathways activated?
when energy supply is high
27
what is the name of the enzyme that catalyses making glycogen?
glycogen synthase
28
what is the name of the enzyme that catalyses breaking down glycogen?
glycogen phosphorylase
29
what is glycogen synthase activated by?
glucose-6-phosphate
30
what is glycogen synthase inhibited by?
ATP which is the signal for high energy
31
what is glycogen phosphorylase activated by?
AMP which is the signal for low energy
32
what is glycogen phosphorylase inhibited by?
glucose-6-phosphate