Organelles 1 Flashcards

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1
Q

Which Organelles are composed of the Secretory Pathway?

A
Endoplasmic Reticulum 
Golgi 
Lysosome
Plasma Membrane 
Secreted from cell
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2
Q

Which Organelles are included into the Non-secretory pathway?

A

Nucleus
Mitochondria
Peroxisome
Cytosol

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3
Q

Where does Translation begin

A

Free Ribsome

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4
Q

Which organelles are Exception to the Antero/RetroGrade transportation rule? Having there Own Transportation Mechanisms?

A

Mitochondria

Peroxisomes

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5
Q

Examples of Polarized Cells?

Which membrane surface is the Glut2 portion found on?

A

Apical, Basolateral Surfaces

The Glut2 is found on the apical Surface of the Apical surface of the Enterocyte.

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6
Q

Which is the Cytoplamsic portion of the Inner Nuclear Membrane

A

The most inner portion

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7
Q
Where is the signal sequence located? 
A. Cytosol 
B. Hydrophobic Portion of the Peptide
C. Signal Sequence 
D. MRNA
E. Amino Acid Sequence
A

Amino Acid Sequence

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8
Q
Nucelar Intermembrane Space continues as...
A. Endoplasmic Outer Membrane 
B. Endoplasmic Inner Membrane 
C.  Outer Membrane of the Golgi. 
D. Lumen of Endoplasmic Reticulum 
E. Nuclear Membrane
A

Lumen of the Endoplasmic Reticulum

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9
Q

Seen within the Pathology there isn’t a distinction within the separations of Lamina A-C. As a result several of the Nuclear structure may completely or partially compromised, this in turn disrupts the replication process of cytokinesis. As a result disrupting the Outer nuclear membrane as well.
Which membrane is most likely to be affected?
A. Inner Endoplasmic Ret.Membrane
B. None
C. Outer Endoplasmic Ret. Membrane
D. Golgi Membrane
E. Plasma Membrane

A

Outer Endo. Membrane

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10
Q
Once the receptor is bound it then...
A. Holds on to the Signal Sequence 
B. Brings the Complex to the targeted organelle 
C. Signal for Transduction 
D. Sent for ERAD
A

B. Brings the complex to the targeted organelle

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11
Q

You are a attending physician on call within an African Clinic. Your patient was brought in by several of his friends in which mentioned that he has walked from Nigeria to Egypt via the Sahara Desert. As a result of Dehydration your patient is ECF/ ICF have been severely compromised. You as the attending physican begin treatment of aggressive Intravenous Saline Solution. After noticing continuing worsening of your patient. Glucose exams where done. Your patient glucose levels were 30. Noticbly low you begin Dextrose solution, He appears to be coming more aware and alert, however within the next 45 min deteriorates back to an unconscious state. Upon rechecking his glucose level again in the low 30’s. You diagnose his with hypoglycemia. After sending for test and A1c. There are no signs of DM. However distinct levels of Gylocgen. Within a microscopic levels where would you look for next clue?
A. Trans Golgi Network
B. Plasma Membrane
C. GLUT4
D. Plasma Membrane of The Smooth Endoplasmic Reticulum
E. Late Endosome
F. Inner Membrane of the Mitochondria

A

Plasma Membrane of the Smooth ER!
Specifically looking Glucose 6 Phosphotase is which is located in the plasma Membrane of the SER.
Von Gierke Disease

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12
Q
Upon administration of Digixon Sodium blocker, therefore inhabiting the effect of efflux of Calcium, therefore causing an increased contraction. This in turns decreases the functionality of SERCA ATPase. This in turns causing a distinction at which organelle?
A. Smooth ER.
B. Rough ER
C. Golgi
D. Nucleus 
E. Ribosomes
A

Smooth ER

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13
Q
Your patient is seen to be within drug overdose, from heroin, as noted within his chart he has a history of Heroin use. This causes a distinction and enlargement of several livers cell, as this organ is known for drug detoxification. As a result of a biopsy is sent to the lab for educational purposes. The result test are true positive for drug use and abuse; which enzymes is most likely to be seen in remarkable amounts 
A. Cytochrome C
B. Cytochrome 490b
C. Cytochrome 450e
D. Cytochrome p450
A

D. Cytochrome p450

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14
Q

Lipitor(Atorvastatin) is a drug which inhibits the production of cholesterols. Often given for patients with hypercholestermia. Looking within to the mechanisms of the drug and inhibition of HMG-COA Reductase. Upon explanation to your Med 1 2032 class, which organelle is to be effected by this drug.
A. Inner Portion of the Outer Membrane Nuclear Membrane
B. Lumen RER
C. Cytosolic Plasma Membrane of the Smooth ER
D. Exoplasmic Plasma Membrane of the Smooth ER.
E. Both C & D
F. None

A

E Both the Cytoplasmic and Exoplasmic Portion of the plasma Membrane of the Smooth Endoplasmic Ret. As cholesterol is located on both portions of the membrane.
Neither specific

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