Organ Transplantation Flashcards
1
Q
Single absolute contraindication to organ donation
A
Positive HIV status
2
Q
Vascular thrombosis to new organ in minutes
Cause?
Prevention?
A
Hyperacute rejection
Preformed antibodies
ABO matching, lymphocytotoxic crossmatch
3
Q
> 5 days and <3 months
Signs of organ dysfunction
Dx Tx
A
Acute rejection
Biopsy
Steroid boluses, anti-lymphocytic agents (OKT3)
4
Q
Approach to suspected acute liver rejection
A
R/o biliary obstruction by ultrasound
R/o vascular thrombosis by Doppler
5
Q
Approach to suspected acute heart rejection
A
No effective therapy
Routine ventricular biopsies are performed to predict rejection
6
Q
Years after transplant
Gradual loss of organ function
Dx Tx
A
Chronic rejection
Biopsy
No treatment unless it is delayed acute rejection
