Oral pathology Flashcards
Differential diagnosis for a unilocular radiolucency: (8)
PA granuloma, PA cyst, PA abscess, PA fibrous scar, nasopalatine duct cyst, traumatic bone cyst, periapical cemental dysplasia, lateral periodontal cyst, keratocystic odontogenic tumor, ameloblastoma, central giant cell granuloma, metastatic carcinoma
Differential diagnosis for periradicular radiopacities: (6)
Condensing osteitis, idiopathic osteosclerosis, benign fibro-osseous lesion (periapical cementoosseous dysplasia), cementoblastoma, osteoblastoma, odontoma, hypercementosis, exostosis (tori)
Most likely histologic diagnoses for parl?
Spatafore: 52% granulomas, 42% cysts, 2% scars, 4% other
What is a radicular cyst lined with (histologically)?
non-keratinized stratified squamous epithelium of variable thickness
How is the radicular cyst formed (generally)?
Inflammatory proliferation of epithelial cell rests (of Malassez) in the inflamed periodontal ligament
Most widely accepted theory in cyst formation
The epithelial cells proliferate, but only the ones on the outside have access to nutrition, and the ones on the inside necrose, leaving a fluid filled, epithelium lined cavity
How are radicular cysts unlike odontogenic keratocysts or calcifying odontogenic cysts?
the basal cells of radicular cystic lining epithelium are incapable of proliferation by themselves, without stimulation of growth factors or cytokines released by innate and adaptive immune cells during periapical inflammation
What is Gorlin’s cyst
calcifying odontogenic cyst (radiolucent with flecks of radiopacity)
What is the most common malignant salivary gland tumor?
mucoepidermoid carcinoma
what is stafne bone defect?
normal anatomic varient, lies below IAN in posterior mandible, associated with ectopic salivary gland tissue
