oral mucosa II, somatosensory and taste

Question 1

where does the body of the tongue mucosa come from

Answer 1

BA 1

Question 2

where does the root of the tongue mucosa come from

Answer 2

BA 3

Question 3

is there submucosa in the tongue

Answer 3

no

Question 4

touch sensation

Answer 4

Abeta and Adelta

Question 5

warming

Answer 5

c fibers

Question 6

cooling

Answer 6

Adelta

Question 7

pain

Answer 7

Adelta and c fibers

Question 8

innervation of the anterior tongue

Answer 8

CN V

Question 9

innervation of the posterior tongue

Answer 9

CN IX

Question 10

mechanoreceptor cells include

Answer 10

merkel cells and meissner corpuscles

Question 11

thermo and nociception is detected via

Answer 11

bare nerve endings

Question 12

meissners corpuscles

Answer 12

large axons (Abeta), terminate in the superficial lamina propria b/w rete pegs, complexes of nerve ending encapsulated by schwann cells

Question 13

merkel receptors

Answer 13

lare axons (Abeta), terminate at apices of the rete pegs, complexes of nerve endings and merkel cells

Question 14

merkel cells synapse on

Answer 14

primary afferent neurons

Question 15

merkel ending are

Answer 15

slow adapting…respond both to the changing aspects and static phases of the stiumulus

Question 16

meisnner’s ending are

Answer 16

rapidly adapting…respond only to the changing aspects of the stimulus

Question 17

rapid adaptation of the meisnner ending is magnified by

Answer 17

the enfolding schwann cells of the corpuscle that cushion the afferent ending

Question 18

what sensation are meisner or merkel cells able to detect

Answer 18

pain…dynamic range does not extend to the noxious…they have a low threshhold

Question 19

the sensation of spiciness is a part of the

Answer 19

pain system dependent of TRP receptors

Question 20

taste buds are innervated by

Answer 20

CN VII, IX, X

Question 21

fungiform papillae

Answer 21

dorsal ant tongue, BA1, innervated by chorda tympani of VII, monitor food entering mouth, has taste buds, non-k

Question 22

chorda typani of VII is derived from

Answer 22

BA2

Question 23

filiform papillae

Answer 23

heavily keratinized, no buds, innervated by somatosensory fibers (ant tongue…so V)

Question 24

foliate papillae

Answer 24

innervation by IX, lateral posterior tongue, monitor food during chewing, have taste buds (located in the trenches), associated with VE glands

Question 25

circumvallate papillae

Answer 25

c.t core surrounded by trench, posterior tongue, monitor food just before swallowing, innervated by IX, associated with VE glands

Question 26

taste buds in the larynx respond to

Answer 26

deviations from isotonicity to protect the airway

Question 27

there is fn redundancy of the taste buds which make it

Answer 27

resilient to partial taste loss

Question 28

bitter receptors

Answer 28

tas2r, GPC

Question 29

bitter vegetables contain a compound

Answer 29

glucosinolates

Question 30

type I cells of taste buds

Answer 30

dark, express specific proteins, supporting role

Question 31

light cells

Answer 31

have microvilli that reach the taste pore, express receptors for taste substances and respond to taste

Question 32

type II

Answer 32

light type, bitter/sweet/a.a, do not synpase with a primary afferent nerve

Question 33

type III

Answer 33

light type, sour, synapse with primary afferent nerve

Question 34

type II cell synapse

Answer 34

release ATP from a special voltage gated ion channel , CALHM1

Question 35

new taste bud cells differentiate from

Answer 35

basal cells–>precursor that expresses SHH–>all 3 types of bud cells

Question 36

SHH acts on

Answer 36

surrounding cells to maintain taste buds

Question 37

taste bud development

Answer 37

specialization of epithelium into a placode–> cell-cell signalling–> neural innervation–> final differentiation

Question 38

taste buds first appear

Answer 38

EW 8

Question 39

taste pores appear

Answer 39

EW 12